Uses of Vigentin 500mg/62.5mg

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1. What is Vigentin 500mg/62.5mg drug?

Vigentin drug belongs to the group of anti-infectives, antivirals and antifungals, anti-parasitic drugs, also known as penicillin antibiotics with the main ingredients being:
Amoxicillin Clavulanic acid

2. Indications and contraindications for Vigentin 500mg/62.5mg

2.1 Indications to use Vigentin The indications for using the drug include:
Upper respiratory tract infections (including ear, nose, throat) such as sinusitis, otitis media, tonsillitis. Lower respiratory tract infections such as acute and chronic bronchitis, bronchopneumonia, lobar pneumonia. Genitourinary tract infections such as cystitis, pyelonephritis, urethritis. Skin and soft tissue infections such as wound infections, cellulitis, boils, abscesses. Bone and joint infections such as osteomyelitis. Dental infections such as alveolar abscesses. Other infections: septic abortion or abortion, obstetric infections, intra-abdominal infections. Besides the above uses, Vigentin may also be used to treat a number of other conditions that are not listed above. Therefore, before taking the drug, consult your doctor for advice and effective use of the drug.
2.2 Contraindications to the use of Vigentin The cases of contraindications to the use of Vigentin include:
Patients who are allergic to beta-lactams such as penicillins and cephalosporins Patients with a history of jaundice or liver dysfunction due to the use of clavulanate and amoxicillin

3. Usage and dosage of Vigentin 500mg/625mg

Vigentin medicine is prepared in the form of powder for oral suspension with an ivory or yellowish color, porous, non-sticky, with a characteristic aroma and sweet taste. Dosage of Vigentin drug will depend on the patient's disease status and age such as:
Adults and children > 40 kg:
When kidney function is normal: 80 mg/kg body weight/day, divided into 3 times. Do not exceed 3 grams per day.
Renal impairment:
Creatinine clearance greater than 30 ml/min: No dose adjustment required. Creatinine clearance between 10 and 30 ml/min: Dose not to exceed 15 mg/kg body weight/dose, twice daily. Creatinine clearance less than 10 ml/min: Dosage should not exceed 15 mg/kg body weight/day. Hemodialysis: 15 mg/kg body weight/day during and after hemodialysis. Children under 40 kg: Use a dose of 20-40 mg/kg/day, divided into 3 oral doses/day, depending on the degree of infection.
Attention: The above drug dosage is for reference only, patients need to strictly follow the doctor's instructions to ensure effective treatment and avoid unwanted side effects.

4. Undesirable effects when using Vigentin 500mg/62.5mg

Some unwanted effects that may occur when using Vigentin include:
Diarrhea rash Itching Eosinophils increased Nausea or vomiting Hepatitis and cholestatic jaundice Increase transaminase Edema Mild thrombocytopenia Decrease Leukocytes Hemolytic anemia Pseudomembranous colitis Stevens-johnson syndrome Erythema multiforme Dermatitis Toxic epidermal necrolysis Interstitial nephritis Before prescribing a drug, the physician always considers the benefit and effectiveness of the drug. Vigentin carries more than the risk of side effects. However, some cases when using Vigentin can still occur unwanted effects. Therefore, when there are unusual signs after taking the drug, especially when a severe allergic reaction occurs with accompanying signs such as difficulty breathing, severe dizziness, swelling, rash or itching of the face, throat, tongue,... In this case, the patient should immediately notify the medical staff for immediate intervention.

5. Some notes when using Vigentin 500mg/62.5mg

Some notes when using Vigentin medicine include:
Inform your doctor about a history of allergy to Vigentin or any other allergies. Vigentin may contain ingredients that don't work and could cause an allergic reaction or other serious problems. Report any medications you are taking including prescription and nonprescription drugs, herbs and supplements, foods, dyes or preservatives. Pregnancy: There are no adequate and well-controlled studies in pregnant women. Use during pregnancy only when clearly needed. Lactation: Amoxicillin is excreted in breast milk. Therefore, caution should be exercised when administering the drug to a nursing mother. For children, safety and efficacy have been established for pediatric patients weighing ≥ 40 kg, and for children weighing more than 40 kg, it should be carefully evaluated before dosing. Elderly people need to monitor kidney function during treatment. Vigentin is contraindicated in patients with renal failure with creatinine clearance < 30 ml/min and in hemodialysis patients. In patients with hepatic impairment, caution should be exercised in determining the dose of the drug and regular monitoring of liver function is required.

6. Treatment of missed dose and overdose of Vigentin

If you forget to take a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue taking the medicine as scheduled. Do not arbitrarily use the drug twice the dose more than the treatment regimen.
The overdose of Vigentin can cause serious symptoms such as nausea, vomiting, abdominal pain, weakness,... In this case, the patient should stop taking the drug and go to a medical facility to get treatment. examination and treatment.

7. Drug interactions

Drug interactions can reduce the effect of Vigentin, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including vitamins, over-the-counter medicines, prescription drugs, and herbal products. Do not stop, start, or change the dose of any medicine without your doctor's consent without your doctor's consent.
Some drugs that can interact with Vigentin include:
Probenecid: Probenecid reduces the renal tubular secretion of Amoxicillin. Concomitant use of Probenecid with Amoxicillin and Clavulanic acid may increase blood levels of Amoxicillin. Concomitant use is not recommended. Oral Anticoagulants: Concomitant use of oral anticoagulants with Amoxicillin and Clavulanic acid may cause abnormal prolongation of prothrombin time. Dosage of oral anticoagulants should be adjusted. Allopurinol: Concomitant use of Amoxicillin with allopurinol significantly increases the incidence of rash in patients. Oral contraceptives: Clavulanic acid and Amoxicillin may affect the intestinal microflora, leading to decreased estrogen reabsorption and decreased effectiveness of combined estrogen/progesterone oral contraceptives. Amoxicillin can lead to a false-positive reaction in a urine glucose test. Care should be taken to store Vigentin at room temperature, protect from light and avoid humid places. Do not store Vigentin in a humid place or in the freezer. Different medicines will have different storage methods, so read Vigentin's storage instructions carefully on the packaging, or ask your pharmacist. Keep Vigentin out of the reach of children and family pets. When the medicine has been damaged, it cannot be used anymore or has expired, please dispose of the medicine according to the correct procedure.
In short, Vigentin belongs to the group of anti-infectives, antivirals and antifungals, and anti-parasitic drugs. The drug is effective in the treatment of bacterial infections such as respiratory tract infections, urinary tract infections, bone and joint infections, skin and soft tissue infections, etc. However, Vigentin can cause a There are some unwanted effects and drug interactions, so tell your doctor what medicines you are taking to reduce the risk of side effects and at the same time increase the effectiveness of the treatment process.
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