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Valemy is a beta-lactam antibiotic, with the main ingredient being Ceftriaxone. The drug is used to treat bacterial infections. Let's find out detailed information about the drug Valemy through the article below.1. What is Valemy?
Valemy drug has the main ingredient is Ceftriaxone with the content of 1g/vial, prepared in the form of powder for injection, packed in a box of 10 vials of 1g. Valemy is administered intravenously or intramuscularly. Mechanism of action: Ceftriaxone binds to penicillin-binding protein (PBP), which are proteins in the structural components of the cell membrane of bacteria, inhibiting cell wall biosynthesis leading to bactericidal.
2. What does Valemy do?
Valemy is used to treat:
Lyme disease. Urinary tract infections, gonorrhea, syphilis. Pneumonia, typhoid. Sepsis . Osteoarthritis infection. Skin infections. Prophylaxis of infection in surgery.
3. Dosage and usage of Valemy
Dosage:
For adults: Usual therapeutic dose: Inject 1-2 grams/day. If necessary, the dose can be increased to 4 grams/day. Dose to prevent infection: 30 minutes to 2 hours before surgery, 1 gram intravenously, a single dose. For children: Usual dose: 50-75mg/kg/day injection. The total dose should not exceed 2 grams/day. Treatment of meningitis : Starting dose: Injection 100mg/kg (not more than 4g). Then the total daily dose is 100mg/kg/day, for 7-14 days. If infection is caused by Streptococcus pyogenes, treat for at least 10 days. For infants: Usual dose: Inject 50mg/kg/day. For patients with kidney failure, liver failure: Dosage is based on blood indicators. If creatinine clearance <10ml/min: Do not exceed 2g/24 hours. For hemodialysis: 2g dose given at the end of the dialysis session. How to use:
Read the instructions for use of Valemy carefully before using. Valemy is administered intravenously or intramuscularly. How to prepare solution for injection:
Intramuscular injection: Mix 0.25g or 0.5g of Valemy into 2 ml and 1g of Valemy dissolved in 3.5 ml of 1% lidocaine solution. Do not inject more than 1g in the same site. Absolutely do not use lidocaine when injected intravenously. Intravenous injection: Mix 0.25g or 0.5g of Valemy into 5ml and 1g of Valemy in 10ml of sterile distilled water. Inject over 2 to 4 minutes, by intravenous line or directly into a vein. Intravenous infusion: Dilute 2g of Valemy in 40 ml of 0.9% sodium chloride or 5% glucose solution. Infuse for at least 30 minutes. Do not use Ringer lactate to dissolve the infusion.
4. Contraindications of Valemy
Do not use Valemy in the following cases:
Hypersensitivity to Ceftriaxone or any of its ingredients. Hypersensitivity to Cephalosporins, history of allergy to penicillins.
5. Valemy side effects
Common side effects:Skin: Itching, rash, allergic reactions. Digestive system: Diarrhea. Uncommon side effects:
Body as a whole: Fever, edema, phlebitis. Skin: Urticaria. Blood: Leukopenia, eosinophilia, thrombocytopenia. Rare side effects:
Body as a whole: Headache, dizziness, anaphylaxis. Skin: Erythema multiforme. Blood: Coagulation disorders, agranulocytosis, anemia. Digestive system: Colitis. Urinary - genitourinary system: Blood in urine, increased blood creatinine.
6. Notes when using Valemy
Prior to treatment with Valemy, the patient's history of allergy to Cephalosporins, penicillins or other drugs should be carefully investigated. In those allergic to penicillin, there is a risk of cross-allergic reactions. Careful when using Valemy for people with liver failure, kidney failure, need to consider drug dosage. Use caution when using Valemy with pregnant and lactating women. Valemy does not affect the driver and the operation of machinery and equipment.
7. Valemy . drug interactions
Before using Valemy, you should inform your doctor about all drugs you are taking to avoid drug interactions When using Valemy with Colistin, Gentamycin, Furosemide at the same time, there may be an increased possibility of toxicity. Renal: When Valemy is used concomitantly with Probenecid, it may cause a decrease in renal clearance and an increase in plasma concentrations. Do not use Valemy with Aminoside in the same syringe, because it may cause drug precipitation. Valemy is an antibiotic. birth is prescribed by prescription. The drug is used to treat severe bacterial infections. When using Valemy, you should follow your doctor's instructions for your own safety. Call your doctor right away if you have any questions about Valemy.
