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Gentrikin drug is used to treat fungal skin diseases, bacterial infections. The correct use of the drug will bring about effective treatment, but if used in the wrong way can cause some unwanted side effects.
1. What is Gentrikin?
Gentrikin medicine is a medicine prescribed by doctors to treat fungal skin infections, skin infections, Candida skin infections and other conditions.
Gentrikin 10g drug includes the main ingredients: Econazole nitrate 100mg, Triamcinolone acetonide 10m, Gentamycin sulfate (active) 10mg. There are also excipients to put in just enough 1 tube of cream.
Gentrikin medicine is made in the form of a topical cream
Pharmacodynamics
Skin cream is a drug for the treatment of fungal skin diseases containing antifungal agents, antibiotics and corticosteroids.
Econazole nitrate: this is a substance used to treat broad-spectrum fungi, this substance is effective against Gram (+) bacteria. Econazole inhibits the synthesis of sterols or ergosterol. Triamcinolone acetonide: this is a synthetic fluorinated glucocorticoid. The drug is used for injection, oral, topical application or inhalation in the form of alcohol, ester to treat diseases requiring corticosteroids. Gentamicin sulfate: this is an aminoglycoside antibiotic with bactericidal effect through inhibition of bacterial protein synthesis. The bactericidal spectrum of gentamicin includes Gram (-) aerobic bacteria and staphylococci, including penicillinase-producing and methicillin-resistant strains. Pharmacokinetics
When applied to the skin, very little absorption of Econazole from the body, although the substance remains on the skin. Econazole they penetrate most in the stratum corneum, the concentration of inhibition in this stratum corneum is very strong. Less than 1% of a dose is excreted in the feces and urine.
Triamcinolone is mainly absorbed from the gastrointestinal tract, but also well absorbed from the skin, especially when the dressing is closed. Metabolized triamcinolone is excreted in the urine.
When the skin wound is peeled, burned and after washing the wound, Gentamicin and aminoglycosides are absorbed systemically. They are eliminated in plasma from 2 to 3 hours, but this time in neonates and patients with renal impairment is longer.
2. Indications and contraindications for the use of Gentrikin
2.1. Gentrikin drug indication Gentrikin medicine is used to treat the following cases:
Skin infections Tinea pedis, Itching Ringworm In addition, the drug is also used for other fungal skin infections (candida). ). In particular, it is also used to treat ringworm - a fungal infection that causes lightening or darkening of the skin on the neck, chest, arms, or legs. Gentrikin is an azole antifungal agent that works by stopping the growth of fungi.
2.2. Contraindications when using Gentrikin The patient should not use the drug in the following cases:
People with hypersensitivity to all components of the drug Patients with perforated eardrums or cold sores People with syphilis infection tomorrow , tuberculosis , viral infection
3. How to use Gentrikin topical?
Patients should carefully read the instruction sheet if indicated before starting to use Gentrikin and each refill. If you have any questions, ask your doctor or pharmacist for advice.
For external use only: The patient should thoroughly clean and dry the area to be treated. Apply this medication to the affected skin as directed by your doctor, usually once a day (twice a day for candidiasis). Your condition will not get better any faster, but side effects may increase. Apply enough medicine to cover the affected area and some surrounding skin. After using this medicine wash your hands thoroughly. Do not apply this medication to your eyes, nose, mouth, or vagina. Use the drug regularly, avoiding interruptions to ensure effective treatment. Continue using this medication until the prescribed dose is finished, even if symptoms disappear after starting Gentrikin. Patients should not stop taking the drug too soon, because it can lead to drug resistance, increasing the risk of relapse. Notify doctor if condition persists after 2-4 weeks of treatment or worsens at any time.
4. Side effects when using drugs
In addition to the effects of the drug, when patients use Gentikin for treatment, they may experience unwanted side effects as follows:
Irritated skin when using the drug Visual disturbances, glaucoma When encountered If these side effects occur, the patient should notify the doctor or a qualified person for timely treatment to avoid causing any other side effects.
5. Notes when using and storing
5.1. Careful use of the drug Do not use corticosteroids for a long time, to avoid inhibitory damage to the adrenal gland. Use the right amount, exactly as directed by your doctor or as directed by the instruction sheet. When using the drug with signs of skin irritation, poisoning due to overdose, it is necessary to stop and go to the nearest medical facility for timely treatment by doctors or medical professionals. 5.2. Precautions for use in pregnant women and nursing mothers Use caution when using the drug for pregnant and lactating women.
5.3 Storage Store the medicine at the right temperature, in a cool, dry and cool place. Avoid exposure to light in the tube Keep out of reach of children. Gentrikin medicine is used to treat fungal skin diseases, bacterial infections. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to take drugs according to prescription or consult a doctor, professional pharmacist.
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