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Trilaciclib is a kinase inhibitor - an enzyme that promotes cell growth. Trilaciclib is not a cancer medicine but a supportive care medicine. Trilaciclib is used to reduce bone marrow suppression and is indicated to reduce the incidence of chemotherapy-induced myelosuppression in adult patients who have previously received platinum- or topotecan-containing regimens in the treatment of cancer. small cell lung.
1. What does Trilaciclib do?
With the mechanism of action of Trilaciclib is a temporary inhibitor of CDK 4 and 6. Trilaciclib is used to reduce bone marrow suppression. Trilaciclib drug is indicated in the following specific cases:
Patients with small cell lung cancer Patients with previous cancer who have used platinum-containing regimens On the other hand, Trilaciclib drug is not allowed to be prescribed in In the following cases:
Patients with a history of allergy or hypersensitivity to any of the ingredients in Trilaciclib Women who are planning to become pregnant, are pregnant or are breast-feeding
2. How to use Trilaciclib?
Trilaciclib drug is used in intravenous form, the dose is prescribed by the doctor. Even when Trilaciclib is used carefully and correctly by healthcare professionals, Trilaciclib can cause burning sensation and pain due to the risk of the drug leaking out of the vein at the injection site causing injury. tissue. If the injection area becomes swollen, red, or painful during and after the injection, tell your doctor right away.
3. Trilaciclib side effects
The drug Trilaciclib can cause many unwanted effects for users. The specific side effects of Trilaciclib are as follows:
3.1. Fatigue Fatigue is very common during cancer treatment and is a feeling of exhaustion that often doesn't go away with rest. Patients need more time to rest and save energy for more important activities.
3.2. Electrolyte disorders The use of Trilaciclib can affect the normal levels of electrolytes such as potassium, phosphorus, sodium, calcium, ... in the body. Electrolyte values should be closely monitored in patients prescribed Trilaciclib. If the patient's electrolyte levels are too low, the doctor may prescribe an intravenous infusion or an oral supplement of electrolytes. Patients absolutely must not take any electrolyte supplements without consulting the treating doctor.
Anaphylaxis Pneumonia Elevated liver enzymes Rash and allergic skin reactions Menstrual cycle disturbances, irregular sperm production or cessation of production in men.
4. Drug interactions
Trilaciclib blood levels can be affected by certain foods and medications. Trilaciclib drug can interact with some drugs and foods as follows: Dofetilide, dalfampridine, cisplatin, metformin, .... So before taking Trilaciclib, tell your doctor about all medicines and foods that you may not have access to. you are using.
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Reference source: oncolink.org
