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Trihex 2mg drug is used in the supportive treatment of Parkinson's disease and extrapyramidal syndrome. To improve the effectiveness of treatment and ensure safety for health, patients need to take Trihex 2mg medicine as prescribed by the doctor.
1. What is Trihex 2mg?
Trihex 2mg belongs to the group of anti-Parkinson drugs, made in the form of tablets, packing specifications: Bottle of 100 tablets, 500 tablets. The ingredient Trihexyphenidyl HCl (2mg) in Trihex is a synthetic tertiary amine, anti-muscarin, anti-Parkinson. Trihexyphenidyl has inhibitory effects on the peripheral parasympathetic nervous system, antispasmodic smooth muscle, mild pupil dilation, decreased salivation, and inhibits the vagus nerve of the heart.
The exact mechanism of trihexyphenidyl in the treatment of Parkinson's syndrome is unknown, this effect may be due to blockade of centrifugal impulses and inhibition of motor centers in the brain. At low doses, Trihexyphenidyl depresses the central nervous system, but at high doses it produces stimulation that mimics the signs of atropine toxicity.
2. Indications to use Trihex 2mg
Trihex 2mg is indicated for use in the following cases:
Supportive treatment of Parkinson's disease; Reducing extrapyramidal syndrome caused by drugs such as Thioxanthen, Butyrophenon, Phenothiazine.
3. How to take Trihex 2mg
Trihex 2mg is taken orally. Take 3 times a day with meals, if necessary add a 4th dose at bedtime.
In case of taking medicine for dry mouth, should be taken before meals or sucked on sugar-free candies, used with saliva replacement medicine.
If you miss a dose of Trihex 2mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose of Trihex 2mg, do not double the prescribed dose.
Overdose of Trihex 2mg can cause flushing, dry skin, dilated pupils, tachycardia, increased blood pressure, nausea and vomiting. If you have these signs, stop taking Trihex 2mg immediately, consult your treating doctor or go to the nearest medical facility for timely treatment.
4. Dosage of Trihex 2mg
Dose to treat Parkinson's syndrome:
First day take Trihex 1mg, then increase 2mg every 3 - 5 days until reaching 6 - 10mg per day; For patients with Parkinson's syndrome after encephalitis, the dose of Trihex is 12-15mg/day. Dosage of Trihex 2mg to treat extrapyramidal disorders caused by antipsychotics:
Oral dose of Trihex 5 - 15mg/day; Once the disorders are controlled, the dose of Trihex can be stopped or reduced. Trihex dose 2mg for the elderly:
Trihex should only be used in combination with Carbidopa to treat Parkinson's in the elderly, the maintenance dose is 2 - 6mg/day, divided into small doses.
5. Trihex 2mg . side effects
Trihex 2mg medicine can cause the following side effects:
Constipation ; Nausea and vomiting; urinary retention; Fast heart beat; Pupil dilation; Increased intraocular pressure ; Tired; Headache. In case the patient experiences the above side effects, stop taking Trihex 2mg immediately, consult a treating doctor or go to a medical facility for timely treatment.
6. Interactions with other drugs
Possible interactions if Trihex 2mg is used concurrently with the following drugs:
Phenothiazines, Clozapine, antihistamines, Disopyramid, Nefopam;, Amantadine because it may increase anti-muscarin side effects; Tricyclic antidepressants; Metoclopramide; Domperidone; Levodopa, Digoxin is reduced absorption when used concurrently with Trihex; Drugs that are parasympathetic. To avoid possible unwanted interactions, please inform the prescribing doctor of any medications, supplements or vitamins you are taking.
Above is information about uses, doses and precautions when using Trihex 2mg medicine. To ensure safety for health and maximize the effectiveness of treatment, patients need to take Trihex 2mg medicine exactly as directed by their doctor.
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