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Treadox is an antibiotic used in the treatment of respiratory infections, ear, nose and throat infections, kidney infections, urinary system, blood infections. The drug is manufactured in powder form for injection with the main active ingredient being Ceftriaxone. Dosage, usage and side effects of the drug will be in the article below.
1. What is Treadox?
Treadox is an antibiotic used in the treatment of infections of the respiratory tract, urinary tract, skin and digestive system. The drug is administered intravenously, so the dosage form is powder for injection. The main ingredient in 1 vial of Treadox powder for injection is Ceftriaxone (as Ceftriaxon sodium) 1g.2. Uses of the drug Treadox
Treadox is a broad-spectrum antibiotic, in which the main active ingredient is Ceftriaxone, a 3rd generation Cephalosporin. Treadox works to kill bacteria thanks to Ceftriaxone having the function of inhibiting the synthesis of bacterial cell walls, causing bacteria to grow. cannot proceed with division and duplication.
Treadox is extremely stable to the majority of beta lactamases of Gram-negative and Gram-positive bacteria.
According to the latest updates, the antibacterial spectrum of Treadox can list the following bacteria.
Aerobic Gram-negative bacteria: Enterobacter cloacae, Acinetobacter calcoaceticus, Escherichia coli, Enterobacter aerogenes, Haemophilus influenzae (including ampicillin-resistant strains), Klebsiella oxytoca, Klebsiella pneumoniae, Morganella morganii, Proteus vulgaris, Proteus miringitidis, Neisseria meningitidis. Neisseria gonorrhoeae. Gram-positive aerobic strains: Streptococcus pneumoniae, Streptococcus viridans, Streptococcus pyogenes, Staphylococcus aureus Some strains of bacteria ceftriaxone (Treadox): Most strains of C. difficile, Staphylococcus, Enterococcus faccalis. Treadox is extremely poorly absorbed from the gastrointestinal tract, so it should only be administered intravenously, intramuscularly or intravenously. Treadox is widely distributed in body tissues and fluids, has a good penetration mechanism into the cerebrospinal fluid, is transmitted through the placenta and breast milk.
The drug is metabolised in the liver and eliminated mainly by the kidneys.
3. Indications for taking Treadox
Antibiotic Treadox is indicated for the treatment of the following cases.
Patients with respiratory tract infections, ear - nose - throat infections Patients with infections resistant to Cephalosporin I and II Patients with kidney and urinary - genitourinary tract infections. Blood infection, purulent meningitis. Use Treadox to prevent postoperative infections. Bone and joint infections Skin and soft tissue infections Gastrointestinal tract infections, peritonitis, cholecystitis, cholangitis. Contraindications to the use of Treadox:
Treadox is contraindicated in patients with a history of hypersensitivity to any of its components, including ceftriaxone, cephalosporins or penicillins. The patient is a premature infant.
4. Dosage & how to use Treadox
Treadox is administered intravenously or intramuscularly.
Dosage of Treadox for adults and children over 12 years old: 1-2g / day, with severe infections can use up to 4g / day. Dosage of Treadox for children 15 days old to 12 years old: 20-80mg/kg/day. Dosage of Treadox for children under 14 days old: 20-50mg/kg/day Treadox dose for patients with meningitis: 100mg/kg/time/day, maximum 1 day 4g Dosage of Treadox for gonorrhea patients: one injection single dose of 250mg Treadox prophylactic dose before surgery: 1-2g injection 30-90 minutes before surgery.
5. Treadox side effects
Depending on the location and dose in each patient, the side effects of Treadox will be different in each case. Specifically, the side effects that have been recorded before are:
Skin: skin rash, jaundice, inflammation at the injection site. Liver: Increased liver enzymes Kidney: Acute renal failure Digestion: Colitis, diarrhea, nausea Circulation: Hematological disorders Respiratory: Interstitial pneumonia.
6. Notes when using Treadox
It is necessary to closely monitor the use of Treadox in patients with impaired renal and hepatic function. Especially in pregnant and lactating women. Treadox is administered by injection, so patients should take it according to the dose and instructions prescribed by the doctor. Do not arbitrarily increase or decrease the dose of Treadox. Treadox is an injectable antibiotic with the active ingredient Ceftriaxone. The drug is used in the treatment of respiratory and urinary tract infections, prevention of postoperative infections. Treadox is a medicine to be taken as prescribed by a doctor.
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