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Toprevin is a combination medicine, used in the treatment of coughs caused by irritation or allergies. To learn more about the use of the drug, please refer to the article below.
1. What is Toprevin?
Toprevin drug has the main ingredients Acetaminophen, Guaifenesin, Oxomemazine, Sodium benzoate. The drug is in the form of capsules.
Acetaminophen is a non-steroid pain reliever and fever reducer. However, the drug has the main effect of analgesic and antipyretic, almost no anti-inflammatory, antiplatelet effect. This active ingredient lowers body temperature by acting on the central nervous system, reduces fever in febrile patients, but rarely lowers body temperature in normal people. Acetaminophen is also used as a temporary pain reliever in the treatment of mild to moderate pain such as headache; body aches when having a cold or flu; toothache; dysmenorrhea... The most effective medication is to help relieve low-intensity pain of non-visceral origin. Guaifenesin has an expectorant effect by irritating the gastric mucosa, then stimulating secretions in the respiratory tract, increasing the volume and reducing the viscosity of secretions in the respiratory tract. As a result, the drug increases the effectiveness of the cough reflex and makes it easier to expel sputum. This mechanism is different from antitussive drugs, as it does not relieve the cough, but only increases the effectiveness of this reflex. The drug is often indicated for the treatment of cough with thick, thick sputum that is difficult to expectorate due to colds, mild upper respiratory tract infections. This drug is often combined with bronchodilators, nasal decongestants, antihistamines or opioids.
Oxomemazine is a derivative of Phenothiazines, belonging to the group of antihistamines. Histamine is the main substance produced in an allergic reaction. In addition, antihistamines have a mild cough-reducing effect.
2. Uses of Toprevin
Thanks to the pain and cough relief, sputum thinning, anti-allergy effects of the ingredients in the drug, Toprevin is indicated for use in:
Treatment of dry coughs, especially coughs caused by allergies, coughs caused by irritation in adults and children over 1 year of age. Contraindications:
Hypersensitivity to any of the ingredients in the drug; Patients with respiratory failure, liver failure; History of agranulocytosis, urinary retention due to prostate disease or urinary incontinence due to other diseases; Certain types of glaucoma; The patient has anemia many times; People with G6PD deficiency.
3. Dosage and how to use Toprevin
How to use: The drug is taken orally, it should be treated for a short time, when coughing.
Dosage: For adults from 2 to 6 tablets / day, divided into 2 - 3 times.
4. Toprevin side effects
All 3 main ingredients of the drug have the risk of causing side effects, including:
Oxomemazine:
Common: Drowsiness, somnolence, increased viscosity of bronchial secretions, dry mouth, constipation, urinary retention, dizziness, skin erythema; Rare: Anorexia, nausea and vomiting, diarrhea; Very rare: Tardive dyskinesia due to prolonged use of phenothiazine antihistamines, leukopenia or agranulocytosis, irritability is common in infants and nursing infants. Guaifenesin:
Rare: Causes cardiac arrhythmias (including atrial fibrillation, supraventricular tachycardia and extrasystoles) in susceptible patients. Paracetamol:
Uncommon side effects: Skin rash, nausea, vomiting, hematopoietic dysfunction, anemia, nephrotoxicity with long-term abuse, increased liver enzymes, causing cyanosis on the skin; Rare: Hypersensitivity reactions, Steven-Johnson syndrome. When experiencing side effects of the drug, you need to inform your doctor for advice and treatment if necessary.
5. Things to keep in mind when taking Toprevin
Some things you need to keep in mind when taking medicine to ensure safety:
Because the drug has a combination of ingredients, you need to read the ingredients carefully before using, avoid using drugs with similar ingredients. Do not use this medicine for more than 5 days to treat symptoms and do not increase the dose or take more than prescribed. If the symptoms do not improve, you should see a doctor so that the cause can be treated. Pregnant and lactating women: Because the drug can affect these subjects, it should be avoided. If absolutely necessary, consult a doctor. Effects on ability to drive and use machines: Due to the risk of drowsiness and unnecessary accidents. Alcohol should not be used while taking the drug because it increases the risk of liver toxicity; Do not expose to the sun or UV rays. Drug interactions: It should be noted when combining Toprevin with antihypertensive drugs, Atropin, anticonvulsants. Store the medicine in a cool place, out of direct sunlight and out of reach of children. Above is some information about the ingredients, uses and notes when using Toprevin. This is an over-the-counter drug, so you need to read the instructions carefully before taking it, and consult your pharmacist or doctor if necessary.
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