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Topfax is a prescription drug, used in the treatment of many medical conditions such as pharyngitis, sinusitis, pneumonia, pyelonephritis,... So what does Topfax do and how to use the drug? How is this?1. What are the effects of Topfax?
Topfax is an antibiotic drug, made in the form of film-coated tablets with the main ingredient in each tablet is Ofloxacin 200mg.Ofloxacin is a quinolone antibiotic. Ofloxacin has a broad spectrum of antibacterial activity including Pseudomonas aeruginosa, Enterobacteriaceae, Haemophilus influenzae, Staphylococcus, Streptococcus pneumoniae, Neisseria spp. and several other gram-positive bacteria.
Ofloxacin is more effective than ciprofloxacin against strains of bacteria Chlamydia trachomatis, Mycoplasma pneumoniae, Ureaplasma urealyticum. This active ingredient is also active against Mycobacterium leprae and Mycobacterium spp. other. Ofloxacin has a bactericidal effect, however its mechanism of action is not fully known. Like other antibacterial quinolone antibiotics, ofloxacin inhibits DNA-gyrase, an enzyme required in bacterial DNA replication, transcription, and repair.
Topfax is indicated in the following cases:
Genitourinary tract infections: Pyelonephritis Prostatitis Cystitis Epididymitis Infection due to surgery. Respiratory tract infections: Pneumonia Bronchitis Lung abscess Bronchitis Otitis media Sinusitis Tonsillitis. Infections: Blood, bones, joints, eyes, biliary tract, skin and soft tissue, obstetrics and gynecology. Topfax is contraindicated in the following cases:
People with hypersensitivity to Ofloxacin or any component of the drug. Children under 18. Pregnant and lactating women. Glucose-6-phosphate-dehydrogenase deficiency.
2. Dosage and how to use Topfax
Topfax is used orally, should be taken before eating, taking the whole pill. The dosage of Topfax drug should be according to the doctor's prescription, the reference dose in some specific cases is as follows:Prostatitis: Use a dose of 300mg x 2 times / day, for 6 weeks. Uncomplicated gonococcal infections of the cervix and urethra: Use a single dose of 400mg/day. Cervicitis, urethritis not caused by gonorrhea: Use dose 400mg/day, taken once or divided into 2 times. Skin and soft tissue infections: Use dose 400mg x 2 times/day. Uncomplicated urinary tract infections: Use a dose of 200-400mg/day. Complicated upper urinary tract infections: Use 400mg / day, if necessary, increase the dose to 400mg / time x 2 times / day. Acute exacerbation of chronic bronchitis: Use dose 400mg/day, if necessary, increase dose to 400mg/time x 2 times/day. Acute bacterial sinusitis: Use 400mg/day, if necessary, increase dose to 400mg/time x 2 times/day. Dosage of Topfax for adults with renal failure:
Creatinine clearance > 50ml/min: Use the same dose as above, take the drug every 12 hours. Creatinine clearance 10 - 50ml / min: Use the above dose, take the drug every 24 hours. Creatinine clearance < 10ml/min: Use half the dose as above, every 24 hours. Overdose of Topfax is common in the elderly and in cases where the dose cannot be adjusted to match the renal function. Symptoms of drug overdose may include:
Confusion Convulsions Muscle convulsions Hallucinations Tendon-muscular disorders Prolonged QT interval Gastrointestinal disturbances Currently, there is no specific antidote for its use. Topfax overdose. The main method of treatment is to treat the patient's symptoms. Renal function should be monitored to assess the patient's ability to eliminate the drug.
3. Topfax side effects
While using Topfax, you may experience some side effects of the drug.Common side effects of Topfax include:
Nausea, vomiting Diarrhea Abdominal pain Digestive disorders Headache Dizziness Fatigue Insomnia Tremors Nightmares Visual disturbances Rash. Itching Hypersensitivity-type skin reactions Rare side effects of Topfax include:
Hallucinations Psychotic reactions Depression Convulsions Vasculitis Stevens - Johnson syndrome Toxic necrosis of the skin. If you experience any side effects of Topfax, please inform your doctor or immediately go to the nearest medical facility for timely treatment.
4. Interaction of Topfax with other drugs
When Topfax is used together with antacids, iron-containing products, and sucralfate, the absorption of ofloxacin may be reduced. When Topfax is used together with acenocoumarol and warfarin, ofloxacin will increase the effects of these drugs, possibly causing bleeding. Therefore, in case it is necessary to use these drugs in combination, the patient should have the INR checked regularly, and the drug dose adjusted accordingly.Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
