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Topdinir 300 is a product used in the treatment of mild and moderate infections caused by susceptible strains of bacteria. It is extremely important and necessary to learn about drug information, especially instructions for proper use.
1. What is Topdinir? What's the use?
Topdinir 300 is a product manufactured by Maxim Pharmaceuticals Pvt, Ltd.- India with the main ingredient being cefdinir. This is a prescription medication that has the ability to reduce the growth of resistant bacteria. Since then, the drug is effective in the treatment of mild and moderate infections caused by susceptible strains of bacteria.
2. Indications and contraindications of Topdinir 300
2.1. Indications to use Topdinir 300 Topdinir 300 is indicated in the case of infections caused by strains of bacteria sensitive to cefdinir commonly in the following pathologies:
Upper respiratory tract infections, lower respiratory tract infections or both. Folliculitis, impetigo, vasculitis or lymphadenitis, peritonitis, subcutaneous abscess, sweat gland inflammation, infectious atherosclerosis, chronic pyoderma. Patient has nephritis, pyelonephritis, cystitis. Women with uterine adnexitis, metritis , Bartholin's gland inflammation. 2.2. Contraindications Topdinir 300 In addition to those who are suitable for Topdinir 300, this drug is contraindicated in some of the following cases:
People with a history of hypersensitivity to Cefdinir or any of the ingredients of Topdinir. Women during pregnancy and breastfeeding should not take this medicine.
3. How to use and dosage Topdinir 300mg
This is a drug that is taken orally with the ideal time to use it after eating. When using, please pay attention to drink the medicine with filtered water, do not use milk, juice or any other drink. Depending on the patient, the dose of Topdinir 300 is different as follows:
3.1. Topdinir dosage for adults and children over 12 years old With this group of subjects, the recommended dosage of the drug is as follows:
Acute pneumonia: Use at a dose of 300mg every 12 hours. Treatment should last for 10 days to ensure effectiveness. Severe chronic pneumonia: 300mg every 12 hours or 600mg every 24 hours. Treatment should last for 10 days to ensure effectiveness. Sinusitis: Use at a dose of 300mg every 12 hours or 600mg every 24 hours. Treatment should last for 10 days to ensure effectiveness. Pharyngitis/tonsillitis: 300mg every 12 hours or 600mg every 24 hours. Duration of treatment in a day or 10 days depending on the condition of the disease. Uncomplicated skin and soft tissue inflammation: 300mg every 12 hours. Treatment should last for 10 days to ensure effectiveness. 3.2. Dosage of Topdinir for pediatric patients from 6 months to 12 years of age Depending on the type of disease, the reference dose of Topdinir for this group of subjects is as follows:
Severe otitis media: Use Topdinir 300 at a dose of 7mg/kg every 12 hours or 14mg /kg every 24 hours. The duration of treatment is from 5 to 10 days depending on the severity of the disease but not more than 10 days. Severe sinusitis: Use at a dose of 7mg/kg every 12 hours or 14mg/kg every 24 hours. Duration of treatment from 5 to 10 days, not more than 10 days. Pharyngitis/tonsillitis: Use at a dose of 7mg/kg every 12 hours or 14mg/kg every 24 hours. Duration of treatment is from 5 to 10 days or 10 days, not more than 10 days. Uncomplicated dermatitis and skin structure: Use Topdinir 300 at a dose of 7mg/kg every 12 hours. The treatment period is guaranteed to last for 10 days. 3.3. Patients with renal failure Adults: In case of creatinine clearance < 30ml/min, the dose is 300mg/time/day. Pediatric patients: In case of creatinine clearance < 30ml/min/1.72m2, the dose is 7mg/kg/day/time (up to 300mg). 3.4. Patients on hemodialysis Since patients on hemodialysis are at risk of eliminating cefdinir from the body, it is recommended that chronic dialysis patients receive an initial dose of 300 mg and maintain at 7 mg/kg as the condition progresses. controlled.
Please note that the above dosage of Topdinir 300 is for reference only. The detailed dosage of the drug depends on the condition and the progress of the disease, so you need to consult your doctor or medical professional before using the drug.
4. Handling overdose or missed dose
With cases of severe poisoning due to drug overdose, especially if kidney function is impaired, the patient often shows typical signs such as nausea, vomiting, epigastric pain, defecation and convulsions. , at which time hemodialysis can help remove cefdinir from the body.
If you forget a dose of Topdinir 300, take it as soon as you remember it so that the medicine can be effective in treating the disease. However, if it is too close to your next dose, skip the missed dose to avoid an overdose.
5. Be careful when using Topdinir 300
Topdinir 300 should be used with caution in the following patients:
People who have had allergic reactions, such as asthma, rash or urticaria. People with severe kidney disorders need to reduce the dose to ensure safety (when creatinine clearance < 30ml/min). When administering the drug to elderly patients, it is necessary to adjust the dose and dosing interval, taking into account the clinical signs of the patient. In cases where an infection is suspected or uncertain or there are indications for prevention, it is best not to take the drug as this may increase the risk of developing resistant bacteria. Similar to some broad-spectrum antibiotics, long-term use of Topdinir 300 may lead to the development of resistant strains.
6. Drug interactions
During use, Topdinir 300 has the potential to interact with some of the following drugs:
Antacids (containing aluminum or magnesium components): Will reduce drug absorption, so you need to take Topdinir before or at least 2 hours after taking antacids. Probenecid: This ingredient has the ability to inhibit the renal elimination of cefdinir, so it should be used with caution. Iron supplements and iron-containing foods: Taking Topdinir 300 together with substances containing 60mg of iron or vitamins containing 10mg of iron will reduce the range of drug absorption from 80% to 31%. Therefore, if you need to take iron during therapy, make sure to take Topdinir at least 2 hours before or after.
7. Topdinir 300 . side effects
Topdinir 300 has little risk of side effects for users, only some rare side effects include:
Feeling of nausea, vomiting, abdominal pain, stomach disorders, anorexia, constipation. Sometimes the patient feels headache, dizziness, feeling of heaviness in the chest; stomatitis, fungal infections. Some cases of leukopenia, increased liver enzymes, increased BUN. In addition, some very rare side effects but also to watch out for include hypersensitivity, enteritis, interstitial pneumonia.
Above is some information about Topdinir 300 that readers can refer to. Although the drug is available at drugstores nationwide, you should only use it when directed by a specialist to ensure safety for your health.
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