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Tolmasa is an antifungal drug with the main ingredient being Clotrimazol, used in the topical treatment of fungal diseases. The following article provides you with information on how to use, note and time to use Tolmasa.
1. What is Tolmasa?
Tolmasa drug has the main active ingredient is Clotrimazol, which is prepared in the form of topical application.
Clotrimazol has the ability to inhibit the growth of most types of human pathogenic fungi dermatophytes, Malassezia furfur and yeasts. Clotrimazol showed bacteriostatic and fungicidal activity in vitro against isolates of Trichophyton rubrum, T. mentagrophytes, Mycrosporum canis, Epidermophyton floccosum and Candida species, including Candida albicans.
Like other imidazoles, Clotrimazol affects the permeability of the fungal cell wall by interfering with membrane lipids. At therapeutic doses, Clotrimazol inhibits cell wall ergosterol synthesis, but at higher concentrations, drugs with other mechanisms of membrane damage that are not related to sterol synthesis, have not been reported to date. clear that mechanism. Some authors believe that Clotrimazol has an inhibitory effect on nuclear acid synthesis, disrupts lipid and polysaccharide metabolism, this causes damage to cell membranes and increases the permeability of phospholipid membranes of lysosomes of fungal cells.
2. Uses of Tolmasa
Tolmasa is indicated in the following cases:
Local treatment of fungal diseases including ringworm, tinea pedis, inguinal fungus, interstitial fungus caused by T. rubrum, T. mentagrophytes, E. floccosum and M. canis; Candida disease caused by C. albicans and tinea versicolor ( ringworm ) caused by M. furfur. The drug is also used in the case of patients with dermatological conditions suspected of secondary fungal superinfection. Tolmasa is used in certain non-fungal skin infections such as Erythrasma caused by Corynebacterium minutissimum. Contraindications
Tolmasa is contraindicated in patients who are hypersensitive to Clotrimazol or any component of Tolmasa or Imidazoles.
3. How to take Tolmasa
After washing the affected area, apply a thin layer of the medicine gently on the affected area and spread to the surrounding skin. Apply twice a day, morning and evening, for up to 1 month or at least 2 weeks after symptoms disappear to prevent recurrence.
Clinical symptoms usually improve and relieve itching within the first week after application. Although the symptoms are relieved, do not stop the treatment, but continue to apply the drug until the end of the treatment course. If symptoms do not improve after 4 weeks, the diagnosis should be reviewed or the treatment regimen changed. If symptoms become more severe or irritation occurs, the drug should be discontinued. With lesions with many scales, pus, secretions, the diseased skin area should be cleaned before applying the drug.
4. Some notes when using Tolmasa
Tolmasa is for external use only, avoid contact with eyes. In case the patient is hypersensitive or irritated when using Tolmasa, it is necessary to stop using the drug and replace it with another therapy. Pregnancy: Studies have shown that clotrimazol vaginal administration in pregnant women in the second and third trimesters of pregnancy has not shown any adverse effects. However, there are currently no adequate studies in pregnant women in the first trimester, so Tolmasa should only be used when clearly indicated and should be avoided in large areas. Lactation: It is not known whether Tolmasa is excreted in human milk. Tolmasa should be used with caution in lactating women.
5. Undesirable effects when using Tolmasa 500mg
Some side effects may be encountered when using Tolmasa medicine such as: Sensation of stinging, blistering and redness, peeling skin, urticaria, edema, itching, burning sensation, especially when the skin has open lesions. . If the above side effects appear to be mild and unclear, there is no need to discontinue the drug.
When these symptoms do not improve or get worse, stop using Tolmasa and consult your doctor for timely treatment. Tolmasa is a topical cream with the main active ingredient being Clotrimazol. Although symptoms usually improve after about 1 week of taking Tolmasa, you need to take it for at least 2 weeks until the course is over. Before using Tolmasa, you should go to a medical facility to be examined and accurately diagnosed the cause of the disease.
