Uses of Toganin 500

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Toganin-500 has the main ingredient is Arginin hydrochloride, soft capsule dosage form, packing specification, box of 12 blisters x 5 tablets. Complying with the indications, the dose of Toganin -500 will help patients improve the effectiveness of treatment and avoid unwanted side effects.

1. Uses of Toganin-500

The ingredient Arginin hydrochloride in Toganin-500 is a dibasic amino acid in the urea cycle. Its mechanism of action is to stimulate the pituitary and pancreas in turn to release GH (growth hormone), insulin, and prolactin, independent of changes in blood glucose levels, as well as controlled release. adrenaline.
1.1 Indications of the drug Toganin-500 Indication of the drug Toganin-500 in the case of:
Supportive treatment of symptoms of dyspepsia. Nutritional supplementation for patients with impaired urea cycle, including: N - acetyl glutamate synthetase deficiency, type I, II hyperammonemia, citrulinemia and arginosuccinicuria. Maintenance treatment of hyperammonemia in patients with carbamylphosphate synthetase and ornithine carbamyl transferase deficiency. Maintenance therapy for hyperammonemic patients with arginosuccinicuria and citrulinemia. 1.2 Contraindications of Toganin-500 Drug Toganin-500 is contraindicated in the following cases:
People with severe renal failure. People with arginase deficiency cause a disorder of the urea cycle. People with hyperammonemia are caused by organic acids in the blood. People with hypersensitivity to any ingredient of Toganin-500. People with allergies. People after myocardial infarction.

2. Dosage and how to use Toganin-500


How to use: Toganin-500 is taken orally, with food. Patients should swallow Toganin-500 tablets whole with an appropriate amount of water.
Dosage:
Supportive treatment for adults with dyspepsia: Dose 6 - 12 tablets/day. Maintenance treatment of hyperammonemia for infants - 18 years of age with deficiency of carbamylphosphate synthetase and ornithine carbamyl transferase: The dose is 100mg/kg/day x 3-4 times. Nutritional supplements for adults with urea cycle disorders, including: deficiency of the enzyme N - acetyl glutamate synthetase, hyperammonemia type I, II, increased blood citrulin and arginosuccinicuria: Dosage 6-40 tablets/day. Maintenance treatment for neonates - 18 years old with hyperammonemia with arginosuccinicuria and citrulinemia: 100 - 175mg/kg/time x 3 - 4 times/day. Note: Toganin-500 dosage above is for reference only. The specific dose of Toganin-500 depends on the condition and the progression of the disease. To get the right dose of Toganin-500, patients should consult a doctor or healthcare professional.
How to deal with missed dose, overdose of Toganin-500:
In case of forgetting dose of Toganin-500, it is advisable to supplement as soon as possible. However, if it is almost time for the next dose, skip the missed dose of Toganin-500 and use a new dose. When using Toganin-500 in overdose, brain edema or renal tubular metabolic acidosis, death (in children) may occur... Patients need to stop taking the drug immediately and go to a medical facility. nearest hospital for prompt treatment.

3. Undesirable effects of the drug Toganin-500


When using Toganin-500, patients may experience undesirable effects such as:
Common: Local pulse stimulation, increased body temperature, frostbite, headache, vomiting, flushing, nausea. Rare: Thrombocytopenia, anaphylactic reactions, edema and pain. Patients with cirrhosis of the liver may have abdominal cramps, phlebitis, abdominal distention. Patients with kidney disease, diabetes, liver, severe cough may have hyperkalemia. Patients with diabetes may experience hypophosphataemia. Patients with asthma may experience increased levels of blood urea nitrogen, serum creatinine, decreased FEV1 and increased exhaled nitric oxide. for appropriate treatment.

4. Toganin-500 drug interactions


Toganin-500 may have drug interactions if combined with:
Diuretics to reduce potassium consumption; Oral antidiabetic drugs such as sulfonylureas; Diuretics such as Aminophyllin, Thiazide, Xylitol. Spironolactone drug. Oral contraceptives combine progesterone and estrogen. Therefore, before being prescribed Toganin-500, patients should inform their doctors about all the drugs they are using, including functional foods. The doctor will base on that to prescribe the appropriate prescription.

5. Note when taking Toganin-500


Care should be taken when using Toganin-500 for people with kidney disease or anuria due to the drug causing hyperkalemia. Care should be taken when using Toganin-500 for people with severe liver and kidney failure. Pregnant and nursing women should consult their doctor before taking Toganin-500. Absolutely do not use when Toganin-500 has signs of discoloration, mold, watery or expired. Above is all information about Toganin-500 drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Toganin-500 for home treatment because there may be unwanted side effects.

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