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The main ingredient of Argide is Arginin hydrochloride. It is indicated for the maintenance treatment of hyperammonemia in patients with deficiency of the enzymes carbamylphosphate synthetase and ornithine carbamyl transferase, in patients with impaired liver function, hepatitis or cirrhosis.1. What is the use of Argide?
Argide medicine has the main ingredient is arginine hydrochloride with the content of 200mg / 10ml. For the maintenance treatment of hyperammonemia in patients with deficiency of the enzymes carbamylphosphate synthetase and ornithine carbamyl transferase. In addition, Argide 200mg is also used to treat symptoms of indigestion, nutritional supplements for people with urea cycle disorders such as hyperammonemia type I and II, hypercitrulinemia, arginosuccinicuria and N deficiency - acetyl glutamate synthetase.
The mechanism of action of the drug is because Arginin enhances liver detoxification, provides arginine for the urea cycle and helps reduce blood ammonia levels. Arginin can also increase glutathione production and thereby increase the metabolism of toxic substances by the liver. In addition, arginine also has the effect of protecting liver cells, especially cell membranes, preventing fat accumulation in liver cells and enhancing metabolism of glucid, lipid, protid and synthesis of Coenzyme A.
2. Dosage of Argide 10mg
Arginin is not inactivated by gastric acid and is well absorbed from the gastrointestinal tract. Argide is taken orally. The specific dosage of Argide is as follows:
Maintenance treatment of hyperammonemia in patients with carbamylphosphate synthetase deficiency, ornithine carbamyl transferase deficiency: Children from 2 years to 18 years of age: the recommended dose is 100mg/kg daily in divided doses. 3-4 times; Maintenance treatment for patients with hyperammonemia with citrulinemia, arginosuccinicuria: Children from 2 years old to 18 years old, the recommended dose is 100 - 175 mg/kg/time, orally 3 - 4 times/day; Supportive treatment of dyspepsia: Adults can take 3 - 6g/day; Nutritional supplements for people with urea cycle disorders such as hyperammonemia type I and II, hypercitrulinemia, arginosuccinicuria and N-acetyl glutamate synthetase deficiency: Adults take a dose of 3-6g/day depending on the condition. sick. 3. What to do in case of overdose or missed dose of Argide? No research papers available. If an overdose occurs, the patient should stop taking the drug and treat it symptomatically. If the patient forgets a dose of Argide, take it as soon as possible. But if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled.
4. Notes when using Argide Be careful when using Argide for the following patients with diabetes, biliary obstruction; Patients should stop taking the drug when abdominal pain and diarrhea; Pregnancy: There are no data on the use of Argide in pregnant women. Therefore, pregnant women should only use the drug when absolutely necessary and under the direction of a doctor; Lactation: It is not known whether Argide passes into breast milk. Therefore, lactating women should use caution when taking the drug under the direction of a physician. In summary, Argide has a role in the treatment of liver dysfunction, inflammation and cirrhosis, and hyperammonemia. The drug is relatively well tolerated, sometimes high doses can cause abdominal pain, diarrhea. Therefore, patients should use Argide exactly as directed by their doctor or pharmacist.
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