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Tobradex medicine 5ml is often used to treat eye inflammation, eye infection,... During the use of Tobradex, patients need to follow the doctor's instructions on dosage and small frequency. drugs to ensure safety and bring high results.
1. What is Tobradex 5ml?
Tobradex 5ml is an ophthalmic suspension used for the treatment of steroid-responsive ocular inflammation when there is a superficial bacterial infection of the eye or a high risk of ocular infection. Tobradex is a product of S.A. Alcon - Couvreur N.V, prepared as a sterile ivory suspension, with the following specific active ingredients:Main active ingredients: Tobramycin 3mg (0.3%) and dexamethasone 1mg (0.1%) . Preservative: Benzalkonium chloride (0.01 % rate). Other excipients are sufficient: Sodium Chloride, Edetate Disodium, Tyloxapol, Sodium Sulfate, Hydroxyethyl Cellulose, Sodium Hydroxide (helps to adjust pH), Sulfuric Acid and purified water.
2. Indications and uses of Tobradex
2.1 Indications to use Tobradex Drug Tobradex 5ml is usually indicated for use in some of the following cases:
Treatment of steroid-responsive eye inflammation. Treatment of blepharitis conjunctivitis, keratitis, ocular conjunctivitis, inflammation of the anterior part of the eyeball. Reduces swelling, pain, irritation, inflammation, redness and edema. Treatment of chronic anterior uveitis, some lesions caused by foreign bodies, chemicals, radiation or thermal burns. Treatment of cases where there is a high risk of superficial bacterial infections of the eye or the presence of a large number of bacteria in the eye. In addition, the components tobramycin and dexamethasone in Tobradex 5ml are also active against the following bacteria causing eye diseases:
Streptococci: Some species do not cause hemolysis and group A beta-hemolytic species, Streptococcus pneumoniae bacteria. Staphylococci: Includes S. epidermidis, S. aureus and penicillin-resistant strains. Strains of Escherichia coli, haemophilus influenzae, pseudomonas aeruginosa, proteus vulgaris, acinetobacter calcoaceticus and Neisseria. 2.2 Uses of the drug Tobradex 5ml Tobradex eye drops solution for stye treatment includes a combination of two main active ingredients, dexamethasone and tobramycin, in which:
Tobramycin: An antibiotic of the Aminoglycoside group, with broad effects. on many strains of bacteria causing eye infections. Some studies show that the active ingredient tobramycin irreversibly binds to the 30S unit of the ribosome organelle (helps to synthesize polypeptide chains of living organisms, thereby inhibiting protein synthesis of bacterial strains, inhibit the formation, growth and destruction of bacteria without harming the user's body). However, the active ingredient tobramycin cannot completely prevent the effects of viral, fungal or chlamydial strains. Most anaerobic bacteria are also not affected by tobramycin, instead the drug is active mainly against bacteria, rarely S.aureus and E.coli. Active ingredient dexamethasone: Acts as a steroid, has anti-inflammatory, immunosuppressive and anti-allergic effects. This ingredient also has the ability to balance fluids and electrolytes in the body, but has not yet been used much in clinical practice.
3. Dosage and how to use Tobradex 5ml
3.1 Dosage of Tobradex 5ml The following is the general recommended dose for the use of Tobradex:
Instill in each eye (including the non-inflammatory eye) about 1-2 drops, with a frequency of 4-6 times / day. During the first 2 days, the patient can increase the dose of Tobradex compared to the recommended dose, namely about 1-2 drops every 2 hours. If you notice an improvement in your eye symptoms, you can adjust the dose down and reduce the frequency of eye drops, but abrupt discontinuation should be avoided. Tobradex eye ointment can be used at night instead of eye drops. 3.2 How to use Tobradex 5ml Before instilling eye drops, patients should wash their hands and dry their hands to avoid further eye contact with bacteria. Shake the suspension well before instilling the eyes, absolutely do not let the tip of the vial come into direct contact with the eyes or any other damaged or infected surface to prevent infection.
After instillation, you need to close the cap tightly and store it in a dry place. In case you are using other eye drops, use the dilator at least 5 minutes apart and apply the eye ointment last. Patients should also not abuse or arbitrarily prolong the drug for another 2-3 days when the disease is cured, because this can lead to antibiotic resistance.
3.3 What to do in case of overdose or missed dose of Tobradex 5ml? Treatment of overdose Tobradex 5ml
When overdosing Tobradex eye drops 5ml, patients may experience some symptoms such as congestion, appearance of spots, edema, increased tearing and itchy eyelids. To treat this condition, you need to quickly rinse your eyes with clean warm water to help wash away the active ingredients in the medicine. If serious overdose reactions occur, notify your doctor immediately or seek medical attention.
Management of missed dose Tobradex 5ml
In case you miss a dose of Tobradex, you need to replenish the medicine as soon as possible. If it is almost time for your next dose, you should skip the missed dose and take your next dose as scheduled. You should never take a double dose as prescribed, as there is a potential risk of overdose.
4. Some side effects when using Tobradex 5ml
When using Tobradex, patients may experience some of the following common side effects:
Itching or discomfort in the eyes. Eye pain, glaucoma, eye irritation. Eye irritation, blurred vision, red eyes, red conjunctiva. Eye congestion, eyelid edema, eyelid redness, pupil dilation. Increased tearing or sensitivity to light. Secondary bacterial infection. Taste change. Headache, dizziness, nausea, rash, facial swelling, itching. There is a feeling of discomfort in the abdomen. If you notice any of the above symptoms, you should tell your doctor right away. These side effects can vary from person to person, ranging from mild to severe. Therefore, monitoring the body's reactions after using the drug is extremely important, helping to timely handle when health risks occur.
5. Contraindications to the use of Tobradex 5ml
Tobradex should be avoided in the following specific cases:
People with a history of allergy to active ingredients such as tobramycin, dexamethasone, or hypersensitivity to any of the excipients in the drug. Herpes simplex keratoconjunctivitis. People with chickenpox, cowpox and some other viral infections of the conjunctiva or cornea. People infected with Mycobacterium bacteria in the eye. People with fungal infections of the structures or parts of the eye. The person who had just undergone surgery to remove a corneal foreign body had no complications. During prolonged steroid therapy, you need to be aware of the risk of fungal infection of the cornea. If a superinfection occurs, immediate action should be taken.
6. Some notes when using Tobradex 5ml
6.1 What should be kept in mind during Tobradex treatment? Tobradex 5ml eye drops should be kept sterile until opened. You need to avoid the drug being contaminated or contaminated, and at the same time do not use Tobradex if you notice strange signs such as discoloration, cloudiness, mold, etc. In addition, you also need to note a few things as follows. Here in the process of taking Tobradex 5ml:
Do not inject Tobradex into the eyes. In case of hypersensitivity reactions such as red rash, itching, ... you need to stop taking the drug immediately. The drug contains dexamethasone (corticosteroid) that has the ability to weaken the resistance, easily create opportunities for fungal infections, viral infections, bacterial infections and hide the symptoms of the disease. Avoid using contact lenses while taking Tobradex. This eye drop contains benzalkonium chloride which has the potential to cause eye irritation. 6.2 Interactions of Tobradex 5ml When treating with Tobradex 5ml, you need to be careful when taking the drug at the same time as other drugs to prevent the risk of harmful interactions. You need to avoid using Tobradex together with neurotoxic, nephrotoxic or auditory substances, beta-lactam antibiotics, neuromuscular blocking drugs.
To minimize the risk of drug interactions, you need to provide your doctor with complete information about the drugs you are taking. This includes herbal medicines, prescription drugs, over-the-counter medicines or health foods. In addition, when using Tobradex, you also need to avoid arbitrarily stopping the drug or adjusting the dose without the permission of the pharmacist / doctor.
6.3 Special Situations When Taking Tobradex 5ml Pregnant Women
There is no research and sufficient evidence to show that taking Tobradex 5ml is safe for pregnant women. Therefore, this subject should only use Tobradex when prescribed by a doctor and has assessed that the benefit of the drug outweighs the risk of harm to the fetus.
Breastfeeding women
Currently, there are no accurate statistics on whether Tobradex is excreted in breast milk or not. However, several trials have demonstrated that tobramycin and corticosteroids can be excreted in human milk when administered systemically. Ideally, before using Tobradex 5ml, women who are breastfeeding should consult a doctor and should only use it with approval.
Operators of machinery or vehicles
Most eye drops in general can cause temporary blurred vision or some vision disturbances that affect concentration when operating machinery or drive. If you are in this group of people, be careful when using Tobradex while in need of intense concentration.
6.4 How to store Tobradex medicine 5ml Tobradex medicine should be stored at a temperature of 8 - 27 degrees Celsius. You need to keep the medicine in an upright position, in a dry, cool and clean location. Avoid storing the medicine in a place where there is direct light, because this can easily damage and reduce the effectiveness of the treatment. In addition, it is necessary to store the medicine in a discreet place, out of the reach of children and pets.
Tobradex medicine 5ml is often used to treat eye inflammation, eye infection,... During the use of Tobradex, patients need to follow the doctor's instructions on dosage and small frequency. drugs to ensure safety and bring high results.
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