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Tinidazol HT is a prescription medication used to treat certain medical conditions. So what is Tinidazol HT and how is it used?
1. What is Tinidazol HT?
Tinidazol HT is an antibiotic of the Nitroimidazole group, the drug is made in the form of tablets with the main ingredient in each tablet is Tinidazole 500 mg.Tinidazol HT is indicated in the following cases:
Prophylaxis of postoperative infections caused by anaerobic bacteria, especially infections related to colon, gastric and gynecological surgery . Treatment of infections caused by anaerobic bacteria such as: Intra-abdominal infections such as peritonitis, abscesses. Gynecological infections: endometritis, tubal abscess, endometritis, nonspecific vaginitis. Septicemia Postoperative wound infection. Skin and soft tissue infections. Upper respiratory tract infections and lower respiratory tract infections include: Pneumonia, lung abscess, purulent pleurisy. Acute gingivitis. Genitourinary trichomoniasis in both men and women. Giardia infection. Intestinal amoebiasis Amoeba resides in the liver. Tinidazol HT is contraindicated in the following cases:
People with hypersensitivity to tinidazol or any of its ingredients. Hematopoietic disorders History of acute porphyria. First trimester of pregnancy Women who are breastfeeding. Physical neurological disorder.
2. Dosage and how to use Tinidazol HT
Tinidazol HT is used orally with a single dose during or after food.
Dosage of Tinidazol HT should be according to the doctor's instructions, the reference dose in the following specific cases:
Prevention of postoperative infections: Adults use a single dose of 2g 12 hours before surgery. . Treatment of anaerobic infections in adults: The first day use 2g dose. The following days use dose 1g, once daily or use dose 500mg/time, 2 times/day. The course of treatment is usually 5-6 days is enough, however, the duration of treatment depends on the treatment results; Especially when it is necessary to completely treat infections in some difficult locations, it is necessary to be able to extend the treatment time beyond 7 days. Non-specific vaginitis: Use a single dose of 2g, taken once. Treatment for two consecutive days achieves faster cure. Acute ulcerative gingivitis: Adults use a single dose of 2g. Genitourinary Trichomoniasis: Adults: Use a single dose of 2g. The same treatment is required for both sexual partners. Children: Use a dose of 50 - 70 mg/kg body weight, taken once, a similar dose can be repeated, if necessary. Giardia infection: Adults: Use a single dose of 2g. Children: Use a dose of 50-75 mg/kg, once orally, the same dose can be repeated, if necessary. Intestinal amoebiasis: Adults: Use a dose of 2g, orally once a day, for 2-3 days. Children: Use a dose of 50-60 mg/kg body weight/time/day, 3 days in a row. Liver amoeba: Adults: The total dose is from 4.5 to 12g, depending on the virulence of the infected Entamoeba histolytica. With liver amoeba, treatment may require a combination of purulent drainage with the use of tinidazole. The initial dose is 1.5 - 2g, once a day, for 3 days. Sometimes a 3-day course of treatment is not effective, it is necessary to continue treatment for up to 6 days. Children: Use a dose of 50-60 mg/kg/day, orally once, for 5 consecutive days. Note that mixed infections need to be used in combination with other antibiotics for treatment. There is no specific antidote for Tinidazol HT overdose. Mainly symptomatic and supportive measures, possibly gastric lavage, can also remove tinidazole easily by dialysis.
3. Side effects of Tinidazol HT
Common side effects of Tinidazol HT include:
Nausea. Not good to eat. Stomachache . Temporary change in taste. Less common side effects of Tinidazol HT include:
Dizziness Headache Vomiting Diarrhea. Rare side effects of Tinidazol HT include:
Allergies. Fever. Reversible leukopenia. Inflammation of the mouth. Rash, pruritus, skin rash. Joint pain. Peripheral neuropathy. Dark urine. In the process of using Tinidazol HT, if you notice any unusual symptoms, you should immediately notify your doctor or go to the nearest medical facility for timely treatment.
4. Interaction of Tinidazol HT with other drugs
Cimetidine when used with Tinidazol HT will reduce the elimination of tinidazol from the body. It is possible that because cimetidine inhibits the metabolism of tinidazole in the liver, it increases both therapeutic effects and toxicity. Rifampicin when used with Tinidazol HT will increase the elimination of tinidazole. It may be due to increased metabolism of tinidazole in the liver, thereby reducing the therapeutic effect of the drug. In summary, before using Tinidazol HT, patients should actively know the information about the drug, which not only helps the medication process to be effective but also minimizes unnecessary side effects.
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