Uses of Thecenamin

This is an automatically translated article.

1. What are the effects of Thecenamin?

What is Thecenamin used for? Each Thecenamin tablet has 2mg of Chlorpheniramine, 500mg of Paracetamol and just enough excipients.
Paracetamol (acetaminophen or N - acetyl - p aminophenol) is an active metabolite of phenacetin, is an effective analgesic - antipyretic that can be used to replace aspirin (with equal doses in grams, Paracetamol is not available. effective in the treatment of inflammation). Paracetamol acts at the hypothalamus causing hypothermia, increased heat release due to vasodilation and increased peripheral blood flow (the drug lowers body temperature in febrile people but rarely lowers body temperature in normal people).
Paracetamol (with therapeutic dose) has little effect on respiratory and cardiovascular, does not change the acid - base balance, does not cause irritation, scratch or stomach bleeding like when using salicylates (because paracetamol does not cause acting on systemic cyclooxygenase, acting only on central nervous system prostaglandin/cyclooxygenase). Paracetamol has no effect on platelets or on bleeding time.
As for Chlorpheniramine, this is an antihistamine with very little sedation. As with most antihistamines, chlorpheniramine also has an anticholinergic side effect, but this effect varies widely among individuals. The antihistamine effect of Chlorpheniramine is through the mechanism of competitive blockade of H1 receptors of effector cells.
Indications: Thecenamin is used in the following cases:
Treatment of patients with fever; Treatment for patients with stuffy nose, flu, allergic rhinitis; Treatment for patients with headache, toothache, neuralgia, bone and joint pain. Contraindications : Thecenamin must not be used in the following cases:
Patients with a history of hypersensitivity to any ingredient in Thecenamin; Patients with respiratory and cardiovascular diseases, impaired liver and kidney function; Patients with prostate enlargement, G6DP enzyme deficiency, bladder neck obstruction, pyloric obstruction, angle-closure glaucoma; The patient is in an acute asthma attack; The patient is being treated with MAOIs within 14 days; Women who are breastfeeding.

2. Usage and dosage of Thecenamin

How to use and dose Thecenamin as follows:
How to use:
Thecenamin is made in the form of tablets, so patients use it orally; Take Thecenamin with filtered or boiled water, pay attention to drink the whole tablet, do not chew the tablet; The recommended interval between doses is at least 4 hours. Dosage:
For adults: 1 - 2 tablets/time x 3 - 4 times/day; For children aged 7 - 15: 1 tablet/time x 2 - 3 times/day; For children aged 2 - 6: 1⁄2 - 1 tablet/time x 1-2 times/day. Thecenamin overdose and treatment:
Symptoms: The fatal dose of chlorpheniramine ranges from 25 to 50 mg/kg body weight. Symptoms and signs of overdose Thecenamin include: Paradoxical central nervous system stimulation, sedation, seizures, psychosis, convulsions, apnea, anticholinergic effects, cardiovascular collapse, arrhythmias, dystonic reactions; Treatment: Treatment of symptoms and support of vital functions, special attention should be paid to liver, kidney, heart, respiratory and water and electrolyte balance; Induce vomiting or gastric lavage with syrup of ipecacuanha, then use activated charcoal and bleach to limit absorption; In case of low blood pressure and arrhythmia, it should be treated aggressively. Seizures can be treated with intravenous diazepam or phenytoin; In severe cases, blood transfusion may be required.

3. Thecenamin side effects

Some undesirable effects that patients may encounter when using Thecenamin are:
Thirst, erythema, fatigue, urinary retention, urticaria; Drowsiness, dry mouth, red skin, rash; Hemolytic anemia, granulocytopenia. In addition to the above-mentioned side effects, if the patient experiences any other side effects, it is necessary to notify the doctor immediately for examination and treatment, and to change the dose of the drug to increase the effectiveness of treatment.

4. Be careful when using Thecenamin

Some precautions and precautions when using Thecenamin :
Precautions: In relation to acetaminophen: Paracetamol must be used with caution in patients with pre-existing anemia because cyanosis may not manifest despite dangerously high concentrations of methemoglobin in the blood. In addition, drinking a lot of alcohol can cause increased toxicity to the liver, so avoid or limit alcohol consumption; Related to Chlorpheniramine maleate: chronic lung disease, respiratory depression, somnolence, dry mouth, dizziness, dizziness, blurred vision, psychomotor impairment; there is a risk of urinary retention due to the anticholinergic side effect of Thecenamin; Some notes when using Thecenamin are: During the treatment, the patient should quit beer, wine and other alcoholic foods; During treatment, the patient should be monitored to prevent movement impairment, respiratory failure; Caution when using on pregnant women and nursing mothers: There are no reports of safety when using the drug in pregnant women and nursing mothers, it is recommended to consult a professional doctor. before use.

5. Drug interactions Thecenamin

In the process of using Thecenamin, there may be competition or interaction with other drugs or food, functional foods such as:
Avoid using Thecenamin with alcohol; Caution should be exercised when thecenamin is co-administered with the central nervous system depressant, atropine. To ensure safety during the use of Thecenamin, the patient should list with the doctor all the drugs, herbs, functional foods, herbal medicines, traditional medicines, ... currently in use and not. Self-medication without the prescription of a doctor or pharmacist. This helps to achieve high treatment efficiency, avoiding unwanted incidents.
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