This is an automatically translated article.
Tiphapred 5 is a prescription medicine used in the treatment of certain medical conditions. So what does Tiphapred 5 do and how does it work?
1. What are the effects of Tiphapred 5?
Drug Tiphapred 5 is an anti-inflammatory corticosteroid drug, the drug is made in the form of tablets with the main ingredient in each tablet is 5mg Prednisolone (as Prednisolone acetate). Prednisolone is a glucocorticoid with pronounced anti-inflammatory, antiallergic and immunosuppressive effects.
Tiphapred drug 5mg is indicated in the following cases:
Rheumatoid arthritis Systemic lupus erythematosus Temporal artery inflammation around the nodular artery sarcoidosis Bronchial asthma Ulcerative colitis Hemolytic anemia Agranulocytopenia Severe allergic diseases including anaphylaxis. Acute Leukemia Lymphoma Breast Cancer Prostate cancer in the late stage. Tiphapred 5mg is contraindicated in the following cases:
Severe infections, except for cases of septic shock and tuberculous meningitis. Hypersensitivity to Prednisolone. Skin infections caused by viruses, fungi, or tuberculosis. Taking a live virus vaccine. Notes and precautions when using Tiphapred 5mg drug in the following cases:
Use Tiphapred 5mg with caution in patients:
Osteoporosis Newcomer (intestines, blood vessels) Mental disorders Stomach ulcers Ulcers duodenum Diabetes Hypertension Heart failure Growing children. Because of the risk of adverse events, Tiphapred 5mg should be used with caution in the elderly, preferably at the lowest possible dose and for the shortest possible duration.
Acute adrenal insufficiency may occur when the drug Tiphapred 5 is suddenly stopped after long-term treatment or when there is stress. When taking high doses of Tiphapred 5, it may affect the effectiveness of the vaccine.
2. Dosage and how to use Tiphapred 5mg
Dosage of Tiphapred 5mg depends on the condition and response of the patient. Reference dosage for specific cases is as follows:
Adults: Can use dose from 5 to 60mg/day, usually divided into 2-4 times per day. Children: Can use dose from 0.14-2mg/kg/day or 4-60mg/m2/day, divided into 4 times. How to use Tiphapred 5mg as follows:
The drug is used orally. Dissolve Tiphapred 5 tablets in a sufficient amount of drinking water (about 20-30ml). Do not use milk, tea, coffee or carbonated, alcoholic or calcium drinks to make the medicine.
3. Side effects of the drug Tiphapred 5mg
The most common side effects when using Tiphapred 5 high doses and long-term. Tiphapred 5 inhibits prostaglandin synthesis, reduces the effect of prostaglandins on the gastrointestinal tract, which means that it will lose the effect of inhibiting gastric acid secretion and protect the gastric mucosa.
Common side effects of Tiphapred 5 include:
Insomnia Nervousness excitability. Increased appetite Indigestion Hirsutism. Diabetes. Athritis. Glaucoma Cataract. Nosebleeds Less common side effects of Tiphapred 5 include:
Dizziness Seizures Psychosis Pseudotumor headache Headache Mood changes Delirium Hallucinations Pleasure. Edema Hypertension. Acne Skin atrophy Bruising Hyperpigmentation. Cushing's syndrome Pituitary-adrenal axis suppression Growth retardation Glucose intolerance Decreased potassium - blood Alkalosis Amenorrhea Sodium and water retention Hyperglycemia. Gastric - duodenal ulcers Nausea, vomiting Abdominal distention Esophageal ulcers Pancreatitis. Fracture. Instructions on how to avoid side effects of the drug Tiphapred 5mg:
In the acute treatment indications, except leukemia and anaphylaxis, you should only use Tiphapred 5mg with the lowest dose and for the shortest effective time. fruit. Following long-term treatment with Tiphapred 5mg, inhibition of the hypothalamic-pituitary-adrenal axis is possible. Therefore, it is imperative that you reduce the dose of Tiphapred 5mg step by step, rather than stopping abruptly. The dose reduction procedure of Tiphapred 5mg can be applied, which is 2.5-5mg every 3-7 days, until the physiological dose of Tiphapred 5 is approximately 5mg. If the patient's condition worsens when the dose is reduced, the dose should be increased again and then the dose reduced more slowly. Taking a single dose of Tiphapred 5mg daily has fewer side effects than using divided doses throughout the day. Alternating drug therapy is a good way to minimize adrenal suppression and minimize other side effects. In alternate day therapy, use the drug once every two days in a single dose, in the morning. Monitor and periodically evaluate the parameters of osteoporosis, hematopoiesis, glucose tolerance, eye effects and blood pressure during the use of Tiphapred 5. Prophylaxis of gastric and duodenal ulcers when using Tiphapred drug 5mg high dose with antihistamines or proton pump inhibitors. All patients on long-term treatment with Tiphapred 5mg require additional calcitonin, calcitriol and calcium supplementation to prevent osteoporosis. Persons potentially immunosuppressed by Tiphapred 5 should be warned about the potential for bacterial infection. If you experience any side effects of Tiphapred 5, please inform your doctor immediately or go to the nearest medical facility for timely treatment.
4. Interaction of the drug Tiphapred 5mg with other drugs
Prednisolone in Tiphapred 5mg is an inducer of the cytochrome P450 enzyme, and a substrate of the P450 CYP 3A enzyme. Therefore, Tiphapred 5 affects the metabolism of drugs such as ciclosporin, erythromycin, phenytoin, phenobarbital, ketoconazole, carbamazepine, rifampicin. Phenytoin, phenobarbital, rifampicin and hypokalemic diuretics may decrease the effectiveness of Tiphapred 5mg. Tiphapred 5mg may cause hyperglycemia, so a higher insulin dose adjustment is required. Avoid concomitant use of Tiphapred 5mg with non-steroidal anti-inflammatory drugs, as it may cause gastric ulcer. The above important information is not a substitute for your doctor's advice when taking Tiphapred 5mg. Therefore, to ensure the effectiveness of the treatment process, you should consult with your doctor when using.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
