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Nilkey brand-name drug with the main ingredient is Fluoxetin, which is used to treat psychological problems such as depression, panic anxiety, bulimia and obsessive-compulsive disorder (OCD). .
1. What is Nilkey?
Nilkey drug belongs to the group of bicyclic antidepressants, with the main ingredient being Fluoxetin 20mg and other excipients.
Nilkey is indicated for use in the following cases:
Depression; Binge eating disorder ; Panic syndrome; Obsessive-compulsive disorder.
2. Instructions on how to use Nilkey
Nilkey is usually taken orally. Patients can take the drug once a day (in the morning) or twice a day (morning and afternoon).
Suggested dosage for specific cases:
Treatment of depression:
The starting dose is usually 20mg/day, taken once in the morning. Some people may take a lower dose (ie 5mg/day or 20mg every 2-3 days); The maintenance dose is adjusted according to the individual clinical response. It is usually only after 3-5 weeks that the full therapeutic effect is achieved, so it is not recommended to increase the dose frequently. Treatment of panic syndrome:
The starting dose is 10mg/day, taken once in the morning. After 1 week of taking the drug can be increased to 20mg / day. If there is no sign of improvement after a few weeks of treatment, the dose of Nilkey can be increased to 60mg/day. Treatment of bulimia:
Immediate dose is 60mg/day, can be taken once in the morning or divided into several times a day. Treatment of obsessive-compulsive impulses:
Starting dose of 20mg/day as above. If the dose is over 20mg, it must be divided into 2 times: morning and afternoon. In some cases a dose of 80mg/day may be required, but it is important to always take 3-5 weeks to see results; *Note:
For the elderly and patients with hepatic impairment, it is necessary to reduce the initial dose and reduce the rate of dose increase. Elderly people usually take a starting dose of 10mg/day and do not exceed 60mg/day; Adjust dose in patients with renal impairment to avoid the risk of accumulation of fluoxetine and its metabolite in patients with impaired renal function; There is no information available to determine safety and efficacy in children (<18 years); If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, take your next dose as scheduled and skip the missed dose.
3. Nilkey drug side effects
During treatment, Nilkey can cause side effects such as:
Common side effects: Fatigue, dizziness, sweating, sexual impairment, inability to ejaculate (impotence) ), itching, loss of appetite, nausea, diarrhea, insomnia, skin rash, tremors; Uncommon side effects: Dry mouth, vomiting, urticaria, headache, bronchospasm (asthmatic reaction), urinary retention, digestive disorders; Rare side effects: Serum sickness, epilepsy, vasculitis, extrapyramidal reactions, tachycardia, Parkinson's syndrome, dyskinesia, lupus erythematosus, hepatitis,...; At the beginning of treatment with Nilkey, symptoms of anxiety, restlessness, and trouble sleeping may appear in 10-20% of people treated. Initial and dose-affected nausea reactions may occur in up to 10%.
If you see any of the above side effects, immediately notify a qualified doctor or pharmacist for advice on timely handling.
4. Note when using Nilkey
Nilkey should not be used in the following cases:
History of allergy to Fluoxetin or any ingredient in the formula; Severe renal failure with creatinine clearance <10ml/min; Are taking a monoamine oxidase (MAO) inhibitor. Need to take at least 5 weeks apart; Breastfeeding women. Nilkey should be used with caution in the following cases:
Children or adolescents <18 years of age because of drug use related to suicidal behavior (intentional suicide or attempted suicide); Fluoxetin component in the drug can cause hypoglycemia in diabetics; Fluoxetin can lower the threshold for seizures, so it should be used with special caution in people with a history of epilepsy; There is currently no basis for the safety of using the drug for pregnant women, so only use it when absolutely necessary and under the direction of a doctor; Nilkey may impair thinking, judgment, and movement, and cause drowsiness. Therefore, caution should be exercised when used by people who often drive and operate machinery.
5. Nilkey drug interactions
Nilkey may cause some interactions with the following drugs:
MOA inhibitors (Selegilin, Procarbazine, Furazolidone): increased risk of agitation, confusion, increased blood pressure, convulsions, high fever, symptoms gastrointestinal disorders; Drugs metabolized by the enzyme CYP P450 2D6 and with a narrow therapeutic index (Vinblastin, Encainide, ...), tricyclic antidepressants: dose adjustment of these drugs is required even if only Fluoxetin has been used for 5 weeks before there; Drugs that stimulate Serotonin release: Potentially causing Serotonin syndrome such as agitation, coma, diarrhea,... Maprotilin, Trazodon: May cause plasma concentrations to increase, so the dose should be reduced. Drugs Diazepam: Extend half-life t1/2; Treatment of electric shock: Increased risk of prolonged seizures; Protein-binding drugs such as Digitalis, Digitoxin, anticoagulants, psychoactive drugs: Increases the risk of side effects; Increased concentration of Phenytoin leads to the risk of toxicity. To ensure safe and effective use of medicines, patients should tell their doctors about all medications, health care foods they are taking, and any other medical conditions they have.
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