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The drug Mexold has a fairly common analgesic and antipyretic effect. Usually indicated in cases of mild to moderate pain, this is a fairly safe drug with few side effects when used.
1. What is Mexold 650?
Mexold 650 is a film-coated tablet, in which the main ingredient is Paracetamol with a content of 650 mg.
Normally, Paracetamol is most often used with a strength of 500mg. However, because the drug is best used based on weight (dose is 10-15mg/kg body weight), some people need 650mg to be effective. Paracetamol, also known as Acetaminophen, has analgesic and antipyretic effects. The drug acts on the hypothalamus (temperature regulation center) causing hypothermia, heat loss to the environment increases due to vasodilation and increased peripheral blood flow. Paracetamol lowers body temperature in febrile patients but rarely lowers body temperature in normal people. Paracetamol is also effective in reducing mild to moderate pain. Although classified as an anti-inflammatory pain reliever, it does not have nearly the same anti-inflammatory and antiplatelet effects as other drugs in this class.
This drug, when overdosed, will produce a metabolite, N-acetyl-benzoquinoimin, which is severely toxic to liver cells. This can cause acute liver failure, destroying liver cells if not treated promptly.
2. Indications and contraindications for using Mexold 650mg
Indication of Mexold in the following cases:
Treatment of mild to moderate pain symptoms such as: Headache, throat, teeth, muscles, menstrual pain, back pain, pain after vaccination, body aches due to flu and cold...; Antipyretic effect. Contraindicated for use in the following cases:
Hypersensitivity to the active ingredient Paracetamol or to any other ingredient of the drug; Liver failure, severe kidney failure; Patients with glucose-6-phosphate dehydrogenasse (G6PD) deficiency.
3. Dosage and usage of Mexold 650mg
How to use: Use the drug orally with water. Paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract. So you can drink it anytime. If stomach irritation, it should be taken after meals.
Dosage:
For adults and children from 12 years old: Take 1 tablet / time, every 4-6 hours as needed. Do not take more than 4g/day; For children under 12 years old: Due to the Paracetamol content in this tablet is 650mg, it is not suitable for children under 11 years old.
4. The side effects when using the drug Mexold 650mg
Uncommon side effects:
Skin rash, urticaria; Nausea, vomiting; Decrease in neutrophils and pancytopenia; Thrombocytopenia; Anemia; Renal toxicity with long-term abuse. Rare side effects:
Excessive allergic reactions such as difficulty breathing, swelling of the face, swelling of the throat...; In addition, Paracetamol can cause serious skin side effects such as Stevens-Johnson Syndrome (SJS), acute generalized exanthematous pustulosis (AGEP), toxic epidermal necrolysis (TEN) or Lyell's syndrome. Although rare, these side effects are very serious, so stop using and go to the nearest medical facility for timely treatment.
5. Notes when using the drug Mexold 650mg
When using the drug Mexold 650mg should note the following:
When using the drug, it is necessary to pay attention to the patient's allergy history, accompanying diseases to avoid unwanted effects; Paracetamol overdose can occur when the drug is abused, used in high doses at one time and can cause symptoms such as nausea, vomiting, abdominal pain that appear 2 to 3 hours after taking the drug. More severe, can cause Methemoglobinemia (manifested as cyanosis of the skin and mucous membranes), confusion, confusion, coma, impaired liver function if not promptly treated. When an overdose occurs, it is necessary to immediately notify the medical staff for timely intervention. If possible, use N-acetylcysteine as an antidote. If late treatment is determined to be more than 36 hours after taking the drug, the damaged liver will be difficult to recover; The drug should be used with caution in the following cases: Chronic anemia; people with liver and kidney disease; alcoholism because Paracetamol and alcohol are both harmful to the liver. Avoid the combination with other preparations that also contain Paracetamol which can cause overproduction. During pregnancy, use Paracetamol for pregnant women only when absolutely necessary. In general, it is safe, but the risk of harm to the fetus is not fully understood, so do not abuse it during pregnancy. For nursing women, there have been studies in mothers taking Paracetamol, no undesirable effects have been found in nursing infants, so it can be used, but always consider carefully before using. This is a medication that treats symptoms, so it is still necessary to find the cause of the disease to be able to improve the condition. Use in case of fever should pay attention not to abuse for more than 3 days without finding the cause, if pain relief, do not use more than 10 days if not prescribed by a doctor. Hopefully, through the article, you know the use of Mexold 650mg drug. This is an over-the-counter drug and is widely used, but do not abuse it because it can cause many unwanted effects.
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