This is an automatically translated article.
Lisazin belongs to the group of cardiovascular drugs, indicated for the treatment of dyslipidemia. So how to use Lisazin? Let's find out the necessary information about the drug Lisazin through the article below.
1. What is Lisazin?
Lisazin medicine contains Atorvastatin (in the form of Atorvastatin Calcium Trihydrate) 40mg and other excipients just enough provided by the manufacturer. The drug is prepared in the form of film-coated tablets, packed in a box of 3 blisters, each blister has 10 tablets.
2. What is the effect of Lisazin?
Lisazin drug is indicated for treatment in the following cases:
Support treatment to reduce Total Cholesterol, LDL - Cholesterol, Apolipoprotein B and Triglyceride and to increase HDL - Cholesterol in patients with primary hypercholesterolemia broadcast. Patients with beta-lipoproteinemia disorder. Adjunctive therapy to lower total cholesterol and LDL - cholesterol in patients with homozygous familial hypercholesterolemia when dietary response is not effective. On the other hand, Lisazin is contraindicated in the following cases:
Hypersensitivity to Atorvastatin or other excipients included in the composition of the drug. Allergy to HMG-CoA reductase inhibitors. Patients with liver disease undergoing treatment or with persistent unexplained elevations in serum transaminases. Pregnant and breastfeeding women.
3. Dosage and how to use Lisazin
Lisazin is prepared in the form of film-coated tablets, used orally. The drug should be taken with a full glass of water, the patient can take the medicine at any time of the day, regardless of the meal.
Below is the recommended dose of Lisazin:
Hypercholesterolemia and mixed cholesterol disorders:
Use with the recommended starting dose of 10-20mg/time/day, only once a day. Patients who need a significant reduction in LDL cholesterol (greater than 45%) can start with a dose of 40 mg, given once a day. The maintenance dose is from 10 to 80mg/time/day. After starting treatment and/or increasing the dose of Lisazin, it is necessary to assess blood lipids within 2 to 4 weeks and to adjust the dose accordingly. Homozygous familial hypercholesterolemia:
The recommended dose is 10 - 80mg/day. Combination therapy:
Lisazin can be combined with Resin to increase the effectiveness of treatment. For people with renal failure:
No dose adjustment is required for this group of subjects. Note: This dosage is only recommended by the manufacturer. Depending on the medical condition of each patient, the doctor will prescribe the appropriate dose. Therefore, patients need to follow the doctor's instructions, do not change the dose or give the medicine to others when having similar symptoms.
4. Side effects of the drug Lisazin
The doctor always considers the benefit that Lisazin brings to the patient and the possible risk of side effects to prescribe the appropriate drug. Patients must follow the doctor's instructions to limit the occurrence of unwanted effects. Lisazin is generally well tolerated, and side effects are usually mild and transient. Some side effects may be encountered during the use of the drug as follows:
Body as a whole: Chest pain, facial edema, fever, stiff neck, malaise. Gastrointestinal: Nausea, gastroenteritis, elevated liver enzymes, colitis, vomiting, dry mouth, rectal bleeding, belching, black stools, cholestatic jaundice. Respiratory: Bronchitis, pneumonia, arrhythmia, asthma. Nervous system: Sleep disturbance, dizziness, somnolence, memory impairment, confusion, decreased libido, paresthesia, torticollis, paralysis. Musculoskeletal: Arthritis, leg cramps, bursitis, tenosynovitis, myasthenia gravis, myositis. Skin and Appendages: Itching, contact dermatitis, alopecia, dry skin, sweating, acne, urticaria. Urogenital - genitourinary: Urinary tract infection, polyuria, cystitis, hematuria, dysuria, kidney stones, nocturia, vaginal bleeding, nephritis. Cardiovascular: Palpitations, vasodilation, syncope, headache, orthostatic hypotension, phlebitis, angina, hypertension. Metabolism and nutrition disorders: Hyperglycemia, increased HbA1c, hypoglycemia. Blood and lymphatic system: Anemia, thrombocytopenia, petechiae.
5. Lisazin drug interactions
Tell the doctor about all the drugs the patient is taking such as prescription drugs, over-the-counter drugs, functional foods, herbs... to limit interactions when combining drugs during treatment. treatment course.
Some possible interactions when combining Lisazin with other drugs below:
Indandione anticoagulant combined with Lisazin will increase bleeding time or prothrombin time. Prothrombin time should be monitored in patients receiving concomitant anticoagulants. When used in combination with drugs Cyclosporine, Erythromycin, Gemfibrozil, immunosuppressive drugs, Niacin may cause an increased risk of myopathy. Co-administration with Digoxin may cause a slight increase in the serum concentration of Digoxin.
6. Notes when using Lisazin
Some notes when patients taking Lisazin drug are as follows:
Before treatment with Lisazin, it is necessary to pay attention to exclude the causes of secondary dyslipidemia and measure the lipid indices. Patients should be measured periodically, at intervals of not less than 4 weeks. During treatment with HMG-CoA reductase inhibitors, if creatine kinase levels increase, myositis occurs, or serum liver enzymes are 3 times higher than the upper limit of normal, the dose should be reduced or discontinued. treatment. Use the drug with caution in patients with liver dysfunction, patients who drink a lot of alcohol. Patients should have a reasonable diet before treatment with the drug, should maintain this diet throughout the course of treatment with Lisazin.
7. What to do when missed dose, overdose of Lisazin?
When you forget to take a dose of medicine, the patient can take a missed dose right away, the drug can also be taken 1-2 hours apart from the usual time of taking the medicine. But if it is almost time for your next dose, skip the missed dose and take the next dose as directed by your doctor. Do not double the dose when the patient forgets to take the medicine. In case of overdose, the patient should immediately stop the drug, monitor for symptoms suspected related to overdose. Notify the doctor for timely intervention, immediately take the patient to the nearest medical facility if the symptoms worsen. Above is information about uses, dosage and precautions when using Lisazin. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Lisazin exactly as directed by your doctor.
