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Delorin 10mg is a drug of the rosuvastatin class used to treat hypercholesterolemia and prevent cardiovascular complications. However, the drug also has side effects that users need to be aware of to avoid reducing the effect of the drug.1. Effects of the drug Delorin
Delorin contains rosuvastatin which is a selective and competitive inhibitor of HMG-CoA reductase. This is also an enzyme that catalyzes the conversion of cholesterol precursors to cholesterol, so it reduces the increase in total cholesterol and triglycerides used to treat cases of hypercholesterolemia such as:
Teenagers, adults or children over 10 years of age with primary type IIa hypercholesterolemia, including heterozygous familial hypercholesterolemia or mixed dyslipidemia (type IIIb). Use of delorin as an adjunct to diet when patients do not respond adequately to this regimen and other non-pharmacological therapies such as exercise, weight loss Homozygous familial hypercholesterolemia: Delorin 10mg will help support your diet and other lipid-lowering treatments. Prevention of cardiovascular events in patients assessed to be at high risk Patients receiving treatment for atherosclerosis to delay or slow disease progression
2. How to use Delorin?
The dose of Delorin used for treatment depends on the individual clinical case, but in general, the usual doses are as follows:
Treatment of hypercholesterolemia: the starting dose is usually 5mg or 10mg/day and titrated after 4 week if necessary. The maximum dose is 40 mg/day if severe hypercholesterolemia or cardiovascular risk is present or treatment goals are not reached at 20 mg/day Prevention of cardiovascular events: 20 mg/day Patients over 70 years of age or with renal impairment : Initial dose 5mg/day When concomitant use of drugs that increase rosuvastatin plasma concentrations: maximum dose 10mg/day Children and adolescents 10-17 years of age: starting dose of 5mg/day and dose range 5-20mg/day, titrated according to response and tolerability
Thuốc Delorin 10mg được dùng trong điều trị tăng cholesterol máu
3. Undesirable effects of the drug Delorin
When using Delorin, you may experience side effects such as:
Diabetes Headache, dizziness Constipation, nausea, diarrhea Muscle pain Weakness Tendon disorders Especially 40mg dose can cause side effects. rhabdomyolysis, causing serious damage to the kidneys and liver Delorin is contraindicated in the following cases:
Patients with hypersensitivity to the components of the drug Patients with active liver disease or persistent elevation of transaminases of unknown cause. Severe renal impairment Myopathy Patients taking cyclosporin Pregnant women, lactating women The dose of 40mg is contraindicated in cases of moderate renal failure, hypothyroidism, personal or family history of myopathy. transmission, history of myotoxicity with other HMG-CoA reductase inhibitors, alcoholism, conditions that may cause increased plasma concentrations of rosuvastatin. Above is the information about the drug Delorin that you need to pay attention to in order to use the drug to achieve optimal effectiveness.
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