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Terdein F is a combination of Codein and Terpin Hydrate, the drug is indicated for the purpose of reducing cough, expectorant or supporting the treatment of acute and chronic bronchitis. So how should patients use Terdein F and what should be noted?
1. What is Terdein F?
Terdein F is classified into a group of drugs that act on the respiratory tract with the main ingredients including 2 active ingredients, Codeine 5mg and Terpin hydrate 200mg. Terdein F is a product of Domesco Medical Import-Export Joint Stock Company, circulated in Vietnam and registered with the registration number VNB-2130-04.Terdein F is prepared in the form of soft capsules for oral use, each box includes 10 blisters or 20 blisters, respectively, each blister contains 10 pills.
2. What does Terdein F do?
The effect of the drug Terdein F is a combination of two ingredients Codein and Terpin Hydrate. The Codeine component in Terdein F is essentially a methylmorphine, which replaces the hydrogen position with the hydroxyl group present in the Morphin molecule, so Codeine has similar effects to Morphin, which is analgesic and cough suppressant. However, the advantage of Codeine is that it is better absorbed when taken orally, and at the same time causes less constipation and when used in therapeutic doses, it also causes less bile spasms than Morphine. Codeine also limits the risk of addiction when compared to Morphine.
The analgesic effect of Codeine is applied in cases of mild and moderate pain. Codeine's analgesic mechanism can convert about 10% of a dose to morphine. Although at therapeutic doses, constipation is less, but if the patient takes Codeine for a long time, this side effect still occurs, so Codeine is often used in combination with non-steroidal anti-inflammatory drugs (NSAIDs) to enhance pain relief. Effective pain relief and limited constipation. Codeine has a cough suppressant effect through direct action on the cough center in the medulla oblongata. However, this active ingredient dries up respiratory secretions and increases the consistency of bronchial secretions. Codeine in Terdein F is not effective enough to relieve severe coughs. Another effect of Codeine is to reduce intestinal motility, so it can be used in the treatment of diarrhea in patients with diabetic neuropathy (Not indicated in acute diarrhea and infectious diarrhea). The remaining active ingredient in Terdein F is Terpin hydrate, which works to loosen respiratory secretions by directly stimulating the secretory cells. Therefore, it helps to increase the secretion of bronchial secretions and helps to expel sputum by the cough reflex.
3. Indications and contraindications of Terdein F
Terdein F products are indicated for those who need to relieve cough, loosen phlegm or support the treatment of acute or chronic bronchitis. However, patients should note the following contraindications to Terdein F:
Hypersensitivity to Codeine, Terpin or any other ingredient in Terdein F; Terdein F is not indicated for patients with respiratory failure; Patients cough due to bronchial asthma; Terdein F is contraindicated in pregnant women, nursing mothers and children under 5 years of age; Children under 12 years of age who have just undergone tonsillectomy and/or curettage of V.A should not use Terdein F.
4. Dosage of the drug Terdein F
How to use: Terdein F is prepared in the form of soft capsules for oral use, patients should take the drug with a little water.
The recommended dosage of Terdein F is as follows:
Adults: Take 1 Terdein F pill each time, 3 times a day; Children over 5 years old: Take 1 tablet of Terdein F each time, 1-2 times a day. If you are suffering from a number of chronic diseases and are being treated with many long-term medications such as cardiovascular disease, allergies, etc., please consult your doctor for the best advice on the treatment with Terdein F drug.
Terdein F drug overdose and management:
In the composition of the drug Terdein F contains the active ingredient Codeine, when used in excess of the recommended dose, it can lead to respiratory conditions (slow breathing, Cheyne-Stokes breathing accompanied by Cheyne-Stokes breathing). blue-green mucous membranes), lethargy, lethargy or coma, soft muscles, cold, moist skin, sometimes accompanied by slow pulse and low blood pressure. In case of severe Terdein F poisoning, the patient can stop breathing, collapse, cardiac arrest and lead to death; Treatment of Terdein F overdose: Resuscitation of the patient's breathing must be performed by opening the airway (intubation) and providing controlled respiratory support. After that, naloxone should be given intravenously immediately in case of severe Codeine poisoning.
5. Terdein F . side effects
Patients need to inform their doctor or pharmacist about the side effects encountered during the use of Terdein F, including the following:
Gastrointestinal disturbances such as constipation, nausea, vomiting; Dizziness, drowsiness; Bronchospasm; Skin allergies; Respiratory depression; Excessive sleepiness. In addition, there is a risk of terdein F toxicity with prolonged use or withdrawal syndrome upon abrupt discontinuation of Terdein F.
6. Some notes when using Terdein F
Terdein F should be used with caution in the following patients:
Patients who have recently undergone thoracotomy or laparotomy, because inhibition of the cough reflex by Codeine can lead to postoperative fluid retention. technique in these cases; Patients with increased intracranial pressure; The patient is debilitated. Risk of tolerance and physical dependence following prolonged use of Terdein F. Therefore drugs (especially Codeine) should be used only at the lowest effective dose and for the shortest possible time.
Terdein F (due to Codeine) is not recommended for children with breathing problems (such as difficulty breathing or wheezing during sleep...).
Terdein F medicinal products are absolutely contraindicated in pregnant and lactating patients.
Physicians should warn patients that Terdein F may impair the ability to perform activities requiring mental alertness or physical coordination, therefore caution should be exercised when driving or operating a vehicle. complex machinery.
7. Terdein F . Drug Interactions
Patients taking Terdein F should absolutely not use alcohol or alcoholic beverages; Do not combine Terdein F with morphine antagonists; Use caution when combining Terdein F with CNS depressants or other morphine derivatives. Terdein F is classified into a group of drugs that act on the respiratory tract with the main ingredients including 2 active ingredients, Codeine 5mg and Terpin hydrate 200mg. Terdein F is indicated for cases where it is necessary to relieve cough, loosen phlegm or support the treatment of acute or chronic bronchitis. Patients need to take the medicine exactly as directed to ensure the best treatment effect and avoid unwanted side effects.
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