This is an automatically translated article.
Tempovate cream is a drug in the form of a cream with the main active ingredient Clobetasol propionate used in the treatment of skin diseases in a short time. So what should be noted before using Tempovate cream?
1. Possibility of the effect of topical Tempovate
Clobetasol propionate is a very strong corticosteroid that is not absorbed through the skin, but when applied to the skin, the body has the ability to absorb a certain amount of drug, so it is often used to treat atopic dermatitis. It should be noted that the absorption of the drug is greatly increased when the skin is damaged, so it should be used with caution in open wounds. Clobetasol is an active ingredient in the group of glucocorticoids used topically with anti-inflammatory effects due to its ability to inhibit the synthesis of chemical mediators that produce inflammatory responses and inhibit the release of chemical mediators that cause inflammatory reactions. Allergic reactions such as histamine, serotonin, bradykinin,...2. Indications and contraindications of Tempovate cream
It is indicated for the short-term treatment of redness, itching, scaling, scaling, eczema, psoriasis, dermatitis or other uncomfortable skin conditions. In addition, the drug is also used to treat Eczema and dermatitis such as allergic eczema, otitis externa, photodermatitis, itchy papules, atopic dermatitis, seborrheic dermatitis, insect bites bite for a short time.Some contraindications of Tempovate cream include:
Common acne, rosacea and perioral dermatitis. Itching around the anus and itching in the genital area. Patients with skin diseases caused by viruses such as herpes simplex, chickenpox. Patients with a history of hypersensitivity to any component of the drug. Active ingredient Clobetasol propionate for topical use is not indicated for the treatment of primary infectious skin lesions caused by fungal or bacterial infections, dermatological diseases in children under 1 year of age such as dermatitis and erythema caused by diaper.
3. How to use Tempovate topical
Every day should apply from one to two times with a thin layer of medicine on the affected skin. In case of any abnormality, the drug should be discontinued immediately.
Clobetasol propionate should not be used continuously for more than four weeks without checking the patient's condition. In severe relapses, short courses of treatment may be repeated. In cases where continued corticosteroid therapy is required, a milder form of corticosteroid should be considered.
When dealing with difficult-to-treat lesions such as keratosis pilaris, the anti-inflammatory effect of Clobetasol propionate can be increased by occluding the treated area with polythene film overnight, which is sufficient to bring about a response. desire.
4. Undesirable side effects of topical Tempovate
When used in large amounts for a prolonged period of time or treated over a large area of skin, the drug may be absorbed enough to cause manifestations of hyperadrenocorticism similar to other topical corticosteroids. For infants and children, and especially in the treatment of drugs with a occlusive dressing, this possibility is higher.
When strictly adhered to the dose of less than 50g per week for adults, manifestations of hypothalamic-pituitary-adrenal axis suppression are also usually transient and rapidly reversible upon discontinuation of short-term therapy. .
In addition, long-term high-dose corticosteroid treatment can lead to local skin atrophy such as thinning of the skin, cracking of the skin, and dilation of superficial blood vessels.
Although this is important information about Tempovate topical, it is not a substitute for the advice of your doctor or pharmacist. Therefore, before using, patients need to consult to have appropriate indications.
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