Uses of Tanox

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1. What is Tanox?

What is Tanox? Tanox medicine is prepared in the form of chewable tablets and packaged in a box of 2 blisters x 2 tablets. The main ingredients of the drug include:
Active ingredient: Niclosamide 500mg Excipients just enough for 1 tablet Niclosamide is a chlorinated salicylanilid derivative, used to treat infections of all kinds such as tapeworm (Taenia solium) , fish tapeworm (Diphyllobothrium latum), beef tapeworm (Taenia saginata),) dwarf tapeworm (Hymenolepis nana).
The drug has many advantages such as low cost, effective, low toxicity, so it is widely used. However, the biggest drawback of the drug is that it has no effect on pork tapeworm larvae. Infection with tapeworm larvae is a very dangerous disease, because it is poorly responsive to chemotherapy. Therefore, in cases of infection or suspected infection with tapeworm larvae, Praziquantel is usually the first choice.
Active ingredient Niclosamide kills flukes by acting directly on the head of the fluke. By inhibiting the formation of adenosine triphosphate (ATP) in the mitochondria, the drug interferes with the energy metabolism of the fluke and inhibits the glucose uptake of these parasites as the head and adjacent segments. died. After death, the fluke is expelled in the feces, can see the whole or many small segments. Therefore, after 2 hours of taking the drug, the patient can take a dose of laxative to remove the dead flukes and prevent the possibility of eggs moving to the stomach.

2. Indications and contraindications of the drug Tanox

2.1.Indications of the drug Tanox Use the drug Tanox to treat flukes in the following cases:
Infection with tapeworms including: beef tapeworm, dwarf tapeworm, fish tapeworm. Infection with tapeworm, however, does not kill the eggs of this fluke. Therefore, if the patient is at risk of infection with tapeworm larvae, Praziquantel should be used. 2.2.Contraindications to the use of the drug Tanox People who are allergic and hypersensitivity to Niclosamide or components of the drug Tanox.

3. How to use and dose Tanox

3.1.Usage Tanox is administered by direct chewing. Patients chew Tanox tablets thoroughly and then swallow with a little water, usually after breakfast.
For young children, to use the drug must thoroughly crush Tanox tablets and then mix with a little water to give them to drink. Crushing the drug helps the drug reach the intestines in the form of a powder and to increase the effectiveness, the suspension should be as concentrated as possible, thereby increasing the effect when the drug comes into direct contact with the fluke.
3.2. Dosage for swine tapeworm infection
Single dose of 2 g after breakfast, taking 4 tablets at the same time. In addition, it is necessary to take 1 more antiemetic before treatment with Niclosamide and 1 laxative 2 hours after taking Tanox to prevent infection with tapeworm larvae. Beef tapeworm, fish tapeworm
Take 2 tablets / time x 2 times / day, the first dose is taken right after breakfast and the dose is 1 hour later. In case the patient is often constipated, it is recommended to take 1 dose of laxative in the afternoon the day before taking Tanox. Dwarf tapeworm
Initial dose 2 g in the first day Then reduce to 1 g / day The patient takes the drug for 6 consecutive days. Dosage for children
Children from 2 to 6 years old: the dose is 1/2 the adult dose. Children under 2 years old: use 1/4 of the adult dose. Note: Because dwarf tapeworms often live in the intestinal mucosa, to increase the effectiveness of Tanox medicine, patients should drink a lot of sour juice from fruits when taking the drug to facilitate the contact between the drug and the fluke. get more. If the head of the fluke is still alive, it will develop into an adult after only 14 days, and only 10 days later, eggs can be found in the feces.
Due to the enzymatic breakdown, after a period of use, the head of the fluke may not be recognized in the feces, then the tapeworms or eggs, even if bleach is used. After 3 months, if new tapeworms or eggs are detected in the stool, it means that the patient has been re-infected with T. saginata or T. solium.

4. Notes when using Tanox

4.1.Side effects of Tanox drugs Some common side effects when using Tanox drugs are nausea, vomiting, diarrhea, skin rash, itching. Rare cases of anaphylactic reactions such as angioedema, urticaria, because the drug is poorly absorbed into the body.
Some notes when using Tanox:
It is necessary to do as quickly as possible the expulsion of the tapeworms filled with mature eggs to prevent re-infection and increase the effectiveness of treatment. When removing eggs, absolutely do not let eggs stick to your hands and mouth because it will lead to tapeworm larvae disease, which is a very dangerous disease, because it does not respond to chemotherapy. Pregnancy: Studies have shown that Niclosamide is not mutagenic, teratogenic or fetotoxic. Therefore, the case of tapeworm infection must be treated without delay due to the risk of tapeworm larvae, which is very dangerous for both mother and fetus. Lactation: Niclosamide has not been determined to be excreted in human milk, but very little absorption into the body. Therefore, in case a nursing mother has a tapeworm infection, she should consult a doctor to consider using Tanox. Use caution in driving or operating machinery during treatment with Tanox.

5. Tanox drug interactions

Tanox may interact with alcohol. Alcohol increases the absorption of Niclosamide contained in the drug. Therefore, the patient should not drink alcohol while treating the infection with Tanox.
Above is the basic information about ingredients, usage and notes when using Tanox. Patients should carefully read the instructions for use, consult a doctor if they have any questions and strictly follow the indications and doses to achieve the best treatment results.
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