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Tamidan belongs to the group of endocrine drugs whose main ingredient is levothyroxine, which is used to prevent and treat symptoms of hypothyroidism. The drug is in the form of tablets with a strength of 100 mcg. So what does Tamidan really treat?1. What is Tamidan?
Tamidan has the main ingredient Levothyroxine, a thyroid hormone that is usually indicated in the following cases:
Complementary or replacement therapy for patients with hypothyroid syndrome of any cause at any age. age (including pregnant women) except for transient hypothyroidism during convalescence of subacute thyroiditis. Inhibition of thyrotropin secretion (TSH): This effect may be useful in simple goiter and in Hashimoto's chronic thyroiditis, reducing goiter size. Combination with antithyroid drugs in thyrotoxicosis to prevent goiter and hypothyroidism Contraindications of Tamidan drug include:
Untreated thyroid toxicity and acute myocardial infarction Unresolved adrenal insufficiency Modified because it increases the demand for adrenal hormones in the tissues and can cause acute adrenal insufficiency
2. Dosage of Tamidan
Depending on age, presence of disease, drug effects and blood levels of thyroid hormone, the starting and varying doses of Tamidan will vary. It may take 1-3 weeks after starting treatment with levothyroxine or changing the dose for the treatment's effects to be seen. The specific dosage of Tamidan drug is as follows:
Adults: 12.5-125 mcg/day (oral) There are no indications for Tamidan use in children When an overdose of Tamidan drug can cause symptoms of increased metabolism as endogenous thyrotoxicosis:
Weight loss, increased appetite Restlessness, palpitations Diarrhea, abdominal cramps Sweating, tachycardia, increased blood pressure Arrhythmia, tremor Insomnia, fear of heat Fever, menstrual disorders The treatment of overdose is to reduce or temporarily discontinue Tamidan if signs and symptoms of overdose appear. Gastric lavage may be performed immediately or induce vomiting if there are no other contraindications. Cholestyramine or activated charcoal is also used to reduce absorption of levothyroxine. Use beta-adrenergic blocking agents such as propranolol to counteract many of the sympathomimetic effects. Cardiac glycosides may be used if congestive heart failure is present.
3. Tamidan side effects
In some patients when using Tamidan, side effects may occur such as:
Weight loss Tremors, headache Nausea, vomiting, diarrhea Stomach cramps Stress, irritability, insomnia Increased appetite eating, fever Changes in menstrual cycle Sensitivity to heat Temporary hair loss
4. Be careful when using Tamidan
Some general notes when using Tamidan include:
Need to be very careful when using Tamidan with cardiovascular and hypertensive patients, when there is chest pain or aggravation of heart disease, it is necessary to reduce the dose immediately. diabetes, diabetes insipidus or adrenal insufficiency when treated with levothyroxine will increase disease symptoms. It is necessary to adjust therapy when patients have these concomitant endocrine diseases. In children, when an overdose of Tamidan can cause premature healing of the skull joint If taking a combination of oral anticoagulants, it is necessary to regularly check the prothrombin time to determine whether the dose needs to be adjusted or not Thyroid hormone is not easily passed. Because of the placental barrier, there is no effect on the fetus when the pregnant mother takes thyroid hormone. Although small amounts of thyroid hormone are excreted in milk, it is not harmful to infants and does not cause tumors, but caution should be exercised when Tamidan is used in this population.
5. Drug interactions of Tamidan
Some possible drug interactions with Tamidan use include:
The effect of anticoagulants, coumarins or indandion derivatives may be affected depending on the thyroid status of the patient. When the dose of thyroid hormone is increased, it may be necessary to reduce the anticoagulant dose, adjusting the anticoagulant dose based on the prothrombin time. Thyroid hormone may increase the need for insulin or antidiabetic agents, so careful monitoring of glycemic control is required when initiating or changing thyroid therapy. Beta-adrenergic blocking agents may become less effective when hypothyroidism returns to normal. Cytokines (interferon, interleukin): can cause both hypothyroidism and hyperthyroidism. The effect of cardiac glycosides may be reduced, and serum digitalis levels may be reduced in hyperthyroidism or in subjects with hypothyroidism returning to normal. Concomitant use of Tamidan with ketamine may cause an increase in blood pressure and tachycardia. Concomitant use of Somatrem/Somatropin with thyroid hormone can accelerate bone ossification. Theophylline clearance is reduced in hypothyroid patients and returns to normal when the thyroid gland returns to normal. Co-administration of Tamidan with tricyclic antidepressants may increase the effects and toxicity of both drugs, possibly due to increased sensitivity to catecholamines. Concomitant administration of Tamidan with sympathomimetic agents may increase the risk of coronary insufficiency in patients with coronary artery disease. The information about the drug Tamidan hopes to help users understand more about how to use it as well as note when using it to achieve the best effect in the treatment of the disease.
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