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Tacroz ointment is manufactured by Glenmark Pharmaceuticals LTD, India. It is commonly used by clinicians in the treatment of atopic dermatitis. When used strictly according to the manufacturer's instructions, the drug brings high efficiency in a short time and minimizes potential risks. So what is Tacroz and how does it work? Let's see the article below to equip yourself with the basic knowledge about Tacroz ointment.
1. Uses of Tacroz ointment
Before learning about the uses of Tacroz, we need to know the information "What is Tacroz?". Tacroz is an immunosuppressive topical ointment and is a prescription medication. Therefore, you absolutely cannot buy drugs on your own, but only use them with the permission of your doctor.
Tacroz has the main active ingredient tacrolimus. Once in vivo, tacrolimus binds to specific immunophilin in cells and inhibits calcium ion-related signaling in T cells, thereby inhibiting T cell activation. In addition, tacrolimus inhibits stellate cell proliferation. transcription of genes involved in early T-cell activation and inhibition of chemical mediator release in mast cells and basophils.
Tacroz ointment is used in the treatment of atopic dermatitis. The drug is packaged in a 10g tube. Each tube contains 0.03% tacrolimus and excipients just enough.
2. Indications and contraindications Tacroz . ointment
2.1. Indications Patients with exacerbation of atopic dermatitis unresponsive to topical corticosteroids. Maintenance treatment in patients with atopic dermatitis with a high recurrence rate 2.2. Contraindications Tacroz ointment is absolutely not used for the following subjects:
People who are allergic to any ingredient in Tacroz medicine. Pregnancy: Tacroz induces reproductive toxicity following systemic administration in experimental animals. Lactation: Tacroz is excreted in human milk, so the use of Tacroz ointment is not recommended in this population.
3. How to use Tacroz Ointment
Always read carefully the information on the drug packaging before use, when you have any questions, please immediately discuss with the treating doctor for advice.
3.1. How to use First wash the affected skin area, let it dry, then apply a thin layer of Tacroz to the skin, gently massaging the skin. Note: Do not apply to mucous membranes (eyes, lips, ...) and expose the skin, avoid exposure to light.
3.2. Dosage The drug is indicated in adults and children over 16 years of age. Tacroz Ointment should be used for the first time by dermatologists or specialists with long experience in the field of atopic dermatitis.
For exacerbations: The patient applies to the affected skin area 2 times a day until the lesion is clear or only minor damage remains. If there is a relapse, use can be started again. Tacroz works well, in general, symptoms will be reduced quickly within 1 week, if after 2 weeks there is still no improvement, then consider using other measures. Maintenance treatment with Tacroz: Patients respond well to the drug after 6 weeks of treatment with a dose of 2 times a day: clean lesions, only mild condition, ... can be used for maintenance. Apply twice a week 2 to 3 days apart (eg on Tuesday and Friday). After 1 year of treatment, it is necessary to re-evaluate to decide whether to continue with Tacroz or not. During maintenance therapy, if there is any sign of a flare-up again, start with the twice-daily dosing as outlined above. Some undesirable effects may be encountered when using Tacroz ointment:
Local side effects: burning sensation, itching are very common and resolve within the first week, erythema, paresthesia, irritation. .. Symptoms of acne are rare. Systemic side effects: alcohol intolerance, ocular herpes, increased blood levels of the drug, ... 3.3. What to do in case of an overdose of Tacroz ointment or a missed dose? In case of overdose: Tacroz ointment is applied topically, so overdose is rare. However, swallowing the drug can cause an overdose, if that happens, immediately contact the nearest medical facility for timely treatment.
In case of missed dose: Take another dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next dose as scheduled. Never make up for it by taking a double dose next time.
4. Some notes when using Tacroz . ointment
Tacroz ointment does not cause drowsiness, so it does not affect driving and operating machinery. Medicines should be kept out of reach of children, at a temperature below 30 degrees Celsius, in a dry place, away from direct sunlight. In summary, Tacroz ointment is very effective in the treatment of atopic dermatitis if used according to the doctor's instructions. Tacroz is easy to use, can be carried when going out, traveling, ... However, you should always carefully read the drug information before deciding to use (manufacturer, content, sugar). use, ...) to bring high efficiency and minimize the unwanted effects of Tacroz.
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