This is an automatically translated article.
Pulmorest cough medicine has the main active ingredient, Levodropropizin, which stimulates coughs and reduces symptoms of respiratory diseases. To ensure the effectiveness of treatment and avoid side effects, users need to strictly follow the instructions of the doctor, professional pharmacist.1. What is Pulmorest cough medicine?
Pulmorest syrup has the main active ingredient Levodropropizin 30 mg. Pulmorest cough medicine is effective for symptomatic treatment of irritating cough, dry cough, this is the result of obstruction in bronchitis and spasmodic disease in laryngitis, tracheitis, or may be caused by a connection. related to infection.
2. Active ingredients in Pulmorest . syrup
Each 5 ml of Pulmorest drug solution contains: 30 mg of active ingredient Levodropropizin and excipients just enough.
Pharmacokinetics: In rat and human pharmacokinetic studies, pharmacokinetic and metabolic results were similar. Accordingly, the active ingredient Levodropropizin is rapidly absorbed and distributed in the body after oral administration.
The half-life of the drug is from 1 hour to 2 hours. The rate of binding to plasma proteins ranges from: 11-14%. Pulmorest is eliminated about 83% in the urine within about 96 hours. Taking the next dose of Pulmorest after 6-8 hours did not change the pharmacokinetics of single doses. The pharmacokinetics and bioavailability of the oral solution are similar to those of the syrup form. Pharmacodynamics: Active ingredient Levodropropizin is a cough suppressant with peripheral action in dry cough. The drug has a very low effect on the central nervous system compared to antitussive drugs that also have a central nervous system effect such as codeine.
Mechanism of action: In clinical trials in healthy volunteers, the active ingredient levodropropizin reduced the symptoms of cough induced by citric acid. This effect is maintained for a period of at least 6 hours. When used at therapeutic doses, the drug does not cause any CNS sedation.
3. Indications and contraindications to the use of cough medicine Pulmorest
3.1.Indications Pulmorest is used in the following cases:
The drug is indicated for symptomatic treatment of irritating cough, dry cough, this is the result of congestion such as bronchitis. Spasm diseases such as laryngitis, tracheitis, may be related to infection. 3.2.Contraindications Pulmorest is contraindicated in the following cases:
Pulmorest is contraindicated in patients with hypersensitivity to any of the ingredients in the drug. Do not take Pulmorest when there is increased bronchial secretions, decreased capillary function (Kartagener syndrome or eyelash movement disorder) or patients with severe liver dysfunction. Do not use Pulmorest for pregnant women and lactating women. In addition, Pulmorest contains sugar, so this drug is also contraindicated for people with diabetes.
4. Dosage and how to use Pulmorest
Pulmorest is to be taken orally. Specific drug dosage for each subject is as follows:
In adults and children over 12 years old: Take 10ml of syrup (a full cup), drink 3 times a day and drink at least 6 hours apart each time. Children over 2 years old: 1-2mg/kg x 3 times/day, total dose 3-6mg/kg/day, need to be taken at least 6 hours apart each time. For convenience, the approximate dosage can be used as follows:
Children from 10-20 kg: 3ml x 3 times/day Children from 21-30 kg: 5ml x 3 times/day Children over 30 kg : 10 ml x 3 times/day It should be noted that the treatment still needs to continue as directed by the doctor until the patient's cough symptoms are gone. However, if after a week of treatment with Pulmorest, but the patient does not have a cough or other symptoms, it is necessary to go back to the doctor to be treated or prescribed another medicine.
5. Precautions when using Pulmorest
The active ingredient Levodropropizin, although effective in treating the disease, is not recommended for long-term use. Therefore, after a short period of treatment, but no improvement is seen, the patient needs to see a doctor for advice. Accordingly, patients need to be warned about unwanted side effects so that they can be prevented. Currently, the whole diet using Pulmorest for children under 2 years of age has not been studied. Therefore, the drug Pulmorest should not be used for this subject. Weigh the risks and benefits when using Pulmorest in patients with severe renal impairment (ClCr < 35 ml/min). Active ingredients Methyl paraben, propyl paraben contained in Pulmorest can cause allergic reactions. So consult your doctor before use.6. Undesirable effects when using Pulmorest
During the use of Pulmorest, patients may experience some side effects but very rarely:
Hypersensitivity reactions, Drowsiness, Body weakness Dizziness, fatigue, paralysis, headache, Drowsiness, Low blood pressure, Anxiety, palpitations Tachycardia , Respiratory edema, irritability,... In addition to the side effects listed above, if the body shows symptoms, abnormality, the patient should immediately notify the doctor, pharmacist or medical staff for timely treatment.
7. Pulmorest drug interactions
In studies, there is no interaction with central nervous system drugs such as Phenytoin, Imipramine, Benzodiazepine or antihistamines, corticosteroids,... However, patients need to be careful when using sedative drugs. especially in patients who are sensitive or at risk of affecting the central nervous system.
To ensure safety and effectiveness, avoid side effects, drug interactions, patients should inform their doctor about all drugs, health foods being used and medical history.
In summary, Pulmorest cough medicine has the main active ingredient Levodropropizin, which stimulates coughs and reduces respiratory symptoms. To ensure the effectiveness of treatment and avoid side effects, users need to strictly follow the instructions of the doctor, professional pharmacist.
Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
