This is an automatically translated article.
Vaginal infection is a fairly common disease in women. Therefore, learning about this disease as well as the treatment drugs is very necessary for women. With this article, Vinmec would like to introduce to readers about the uses as well as how to use ponysta,.
1. Vaginal Infections Outline
Vaginal infection is a common gynecological disease in women aged 15-44 years due to complex changes in the vaginal microflora.
Symptoms you may experience when you have vaginitis such as: Itching, swelling and redness, excessive discharge, foul-smelling discharge, burning pain during sex,...
Diagnosis of the disease is based on clinical , vaginal pH and test.
2. What is Ponysta suppository?
Ponysta is a medicine used to treat vaginal infections. Ponysta pills on the market come in the form of soft capsules for vaginal insertion. Each Ponysta tablet contains 100mg of Clotrimazole, 100mg of Clindamycin and some other excipients just enough. In which 2 main components of the drug have separate effects as follows:
Clotrimazol: A broad-spectrum antifungal agent, a derivative of Imidazol. Clotrimazol works through the mechanism of binding to phospholipids in the fungal cell membrane, changing the permeability of the membrane, causing the loss of essential substances in the cell, thereby destroying the fungal cells. Clotrimazol has the ability to kill fungi on the skin, groin, between the feet and some other areas of the body. Clindamycin: At low concentrations has bacteriostatic and bactericidal effects at high concentrations. The mechanism of clindamycin is to bind to the 50S subunit of the ribosome, thereby inhibiting bacterial protein synthesis. Drugs at high concentrations may also have gradual bactericidal activity against susceptible strains of bacteria. Recommended dosage: Place 2 softgels into the vagina every evening for 3 days.
3. Uses of ponysta
Ponysta is indicated for the treatment of mixed vaginitis caused by susceptible bacteria, Gardnerella vaginalis, Candida albicans, Mycoplasma sp. and Mobilicus. Specifically:Vaginal infections caused by Trichomonas or Candida fungi; Bacterial vaginosis; Mixed vaginal infections; Leukemia due to bacterial or fungal infection; Lots of bad gas.
4. Side effects of Ponysta suppositories
For Clotrimazol ingredients:
Reactions immediately after placing the drug: Burning sensation or mild irritation with rare frequency; Very rare side effects: The drug cannot be tolerated, in which case it must be discontinued; Drug allergy: Syncope, hypersensitivity, dyspnea, gastrointestinal disturbance, pain; On the skin and other appendages: Itching, rash; Additional methods of contraception should be used during vaginal administration, as Clotrimazole can destroy latex contraceptives. For the Clindamycin component:
When using the drug vaginally, cases of cervicitis, vaginal inflammation or irritation of the vulva and vagina have been recorded; A small amount of drug is absorbed systemically when vaginally, so there may be side effects like when using systemic drugs; Clindamycin has been reported to cause diarrhea in approximately 20% of patients following systemic administration. Aggravation of pseudomembranous colitis, which may progress during treatment or several weeks after discontinuation of the drug, may result in death. Rash and urticaria are the most common hypersensitivity reactions, occurring in approximately 10% of patients, usually after 1 to 2 weeks of treatment.
5. How to use Ponysta vaginal suppositories
If you have used other vaginal tablets, the way to use Ponysta is the same.
First, clean the vaginal area and hands with clean water, low pH gynecological cleaning solution or diluted saline. In case of having a vaginal medication device: After taking the medicine out of the wrapper, put the medicine in the position that holds the medicine at the end of the device; Gently insert the device into the vagina in the position that feels most comfortable. Able to stand with feet apart and knees bent or lie on his back on a hard surface, knees bent and legs apart; Push the plunger of the device to release the medicine once the device is in the vagina. Remove the instrument from the vagina; Clean according to the manufacturer's instructions for reusable tools. In the absence of a device to use vaginal suppositories: Soak Ponysta with warm water for about 30 seconds to make the pill soft and easier to enter the vagina; Lie on your back, legs wide apart; Clamp the medicine with the index and middle fingers of the dominant hand, and then slowly insert the medicine deep into the vagina; You should not exercise immediately after placing the medicine, lie still for about 15 to 30 minutes to avoid the drug drifting out; Wash your hands thoroughly after applying the medicine.
6. Ponysta Drug Interactions
The use of Ponysta may be affected when taken with other drugs, so please make a list of the medications you are taking with your doctor. Possible drug interactions such as:
Can competitively inhibit the action of the antibiotics Macrolide or Chloramphenicol; Enhanced activity of Primaquin on Pneumocystis jiroveci; In vitro antagonism between clindamycin and erythromycin has been observed; When co-administered with Clotrimazol, tacrolimus serum concentrations of liver transplant patients increased; Synergistic effects between clindamycin and ceftazidim or metronidazol as well as ciprofloxacin against anaerobic strains have been reported.
7. Notes when using Ponysta
Do not use for people with hypersensitivity or history of hypersensitivity to Clindamycin, Lincomycin or Clotrimazole; People who are sensitive to any of the ingredients in Ponysta should not use it; During the use of the drug, if you have abdominal pain, diarrhea, you should stop taking and consult a doctor; Use Ponysta exactly as prescribed. Do not arbitrarily stop taking the drug even if the symptoms have disappeared; Do not take the drug during the menstrual cycle; For pregnant women: In clinical studies, vaginal administration of Clindamycin during the second trimester of pregnancy did not cause adverse effects; For lactating women: No problems have been observed; Ponysta should be used with caution when driving and operating machinery because it can affect the nervous system; Effects will not be guaranteed if you are using the drug and have sex, including using a condom or any other method; For the drug to work best, you should put the drug at night before going to bed; For girls under 12 years old, it is necessary to consult a doctor before using the drug; After using ponysta vaginal suppositories, do not douche too deeply; Keep Ponysta out of reach of children and pets.
8. How to deal with forgetting or overdose of ponysta?
When you forget to take a dose of Ponysta: If you forget a dose of Ponysta, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Do not take double the prescribed dose of Ponysta.
When overdosing: Because the drug Ponysta acts locally and has a low dose, it is less likely to cause toxicity. If the patient experiences a hypersensitivity reaction, the drug should be discontinued.
9. Preservation of Ponysta suppositories Unused Ponysta suppositories should not be left outside the product packaging, to prevent bacteria and mold from entering.
Store Ponysta at a temperature between 25 and 30 degrees Celsius.
In short, Ponysta is indicated for the treatment of bacterial vaginosis. Use medications as prescribed by your doctor to ensure safety and maximize the therapeutic effect.
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