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Spreadim drug with the main ingredient is Ceftazidim, which is prepared in the form of a powder for injection. The drug is indicated for the treatment of bacteremia, meningitis, complicated urinary tract infections... Let's understand the uses of Spreadim and important notes when using Spreadim in the article below.
1. What is Spreadim?
Spreadim medicine has the main ingredient Ceftazidime Pentahydrate + Sodium Carbonate 1g. Spreadim is produced in the form of powder for injection, each box includes a box of 1 vial + 1 ampoule of distilled water for injection of 5 ml.
2. Uses of Spreadim
Spreadim is indicated for the treatment of the following cases:
Septicemia Meningitis Complicated urinary tract infections Lower respiratory tract infections Bone and joint infections Gynecological infections Intra-abdominal infections Skin and soft tissue infections including burn and wound infections
3. Dosage and treatment of Spreadim
3.1. Dosage and Administration: Ceftazidime is injected deep intramuscularly, slowly injected into a vein for 3-5 minutes or intravenously.
Dosage: Spreadim is used according to the doctor's prescription
3.2. Treatment of overdose, missed dose Overdose: Some reactions such as convulsions, encephalopathy, tremor, neuromuscular excitability in some patients with renal failure. Therefore, in the event that Spreadim is used in excess of the prescribed dose and has abnormal symptoms, it is necessary to immediately contact the nearest medical facility. Treatment for patients with renal failure can be hemodialysis or peritoneal dialysis to remove drugs quickly.
Missed dose: During the use of Spreadim, patients need to comply with the treatment schedule of the doctor, to avoid the occurrence of missed doses that reduce the effectiveness of treatment. If you miss a dose of Spreadim, use the missed dose as soon as you remember. But if it is too close to the next dose, skip the missed dose and take the next dose as scheduled. Patients should not use a double dose of Spreadim, because it can cause an overdose.
4. Side effects of Spreadim
In the process of using Spreadim, you may experience some specific side effects as follows:
Common: Local irritation, thrombophlebitis, itchy skin,... Uncommon: Headache, dizziness, fever, Quincke's edema, anaphylaxis, eosinophilia, thrombocytopenia, neutropenia, lymphocytosis, dysgeusia, nausea, vomiting, abdominal pain, diarrhea,... Rare : Agranulocytosis, hemolytic anemia, pseudomembranous colitis, Steven-Johnson syndrome, toxic skin necrosis,...
5. Note when using Spreadim
5.1. Contraindications Spreadim is contraindicated in cases of hypersensitivity to cephalosporins.
5.2. Precautions when using the drug During the use of Spreadim, patients should pay attention to the following issues:
Before starting treatment with Ceftazidime, it is necessary to carefully investigate the patient's allergy history to cephalosporins. , penicillin or other drugs There is a cross-reactivity between cephalosporins and penicillins Caution when co-administering the drug with nephrotoxic drugs Some Enterobacter strains initially susceptible to Ceftazidime may become resistant to the drug during treatment with Ceftazidime and other cephalosporins Ceftazidime may decrease prothrombin time. Therefore, it is necessary to monitor prothrombin time in patients with impaired liver, kidney, malnutrition and if necessary, give vitamin K. When administering the drug to patients with renal impairment, the dose should be reduced. gastrointestinal disease, especially dysentery For pregnant women: Cephalosporins are considered safe during pregnancy. However, there are no adequate and well-controlled studies in pregnant women, so the drug should be used during pregnancy only when clearly needed. For women who are breastfeeding: The drug is excreted via milk, affect the nursing baby, so consult your doctor before taking the medicine
6.Spralin drug interactions
With strong diuretics such as furosemide or aminoglycosides, Ceftazidime is nephrotoxic, so renal function should be monitored during prolonged therapy
Chloramphenicol is antagonized in vitro with Ceftazidime, the combination should be avoided when bactericidal action is required. In the process of using Spralin, patients need to pay attention to follow the doctor's instructions, carefully read the notes before taking to be able to bring the highest treatment effect, limit possible side effects. occurs during drug use.
