Uses of Spiromide

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Spiromide 50/20mg is used in the treatment of some conditions of edema, hypertension, stroke prevention, heart failure,... So what is the use of Spiromide 50/20mg and how to use this drug? how?

1. Uses of Spiromide 50/20mg

Spiromide 50/20mg is made in the form of film-coated tablets, the main ingredients in each tablet include:
Spironolactone 50mg. Furosemide 20mg. Spironolactone is a potassium-sparing diuretic that works to keep potassium levels in the body from getting too low. This medicine is used in the treatment of heart failure , antihypertensive or hypokalemia . In addition, the drug is also used in the treatment of edema in patients with heart failure, cirrhosis, or nephrotic syndrome. Furosemide works to reduce excess water in the body (edema) caused by conditions such as heart failure, liver disease and kidney disease. Thereby helping to alleviate symptoms such as shortness of breath and swelling in the hands, feet and abdomen. Furosemide is also used to treat high blood pressure, to help prevent strokes, heart attacks, and kidney problems. In addition, it can also be used to lower blood calcium levels (hypercalcemia).
Spiromide 50/20mg is indicated in the following cases:
Special edema with secondary hyperaldosteronism. Edema due to heart failure and cirrhosis, nephrotic syndrome. Treatment of high blood pressure, prevention of stroke, heart failure, kidney problems. Used in the treatment of the underlying disease, limiting water intake, eating less salt or using other diuretics with no therapeutic effect. Spiromide 50/20mg is contraindicated in the following cases:
People with a history of allergy to any ingredient of the drug. Liver dysfunction. The patient is suffering from anuria, acute renal failure, severe renal impairment (glomerular filtration rate < 10ml/min). Acidosis in the blood, increased K+ in the blood. Pregnant and lactating women.

2. Dosage and how to use Spiromide 50/20mg

How to use Spiromide 50/20mg:
Take the tablet whole, do not chew or crush the tablet. It is recommended to take the medicine at a fixed time to avoid forgetting a dose. Take the medicine 4 hours before going to bed to avoid having to urinate. The medicine can be taken during or immediately after eating to avoid stomach irritation. The dose of Spiromide 50/20mg should be according to the doctor's prescription. The recommended dose of Spiromide 50/20mg is as follows:
Take 1 - 4 tablets per day, divided into several times a day, depending on the patient's condition and response. If you forget a dose of Spiromide 50/20mg, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.
Overdose of Spiromide 50/20mg can appear symptoms such as dizziness, shortness of breath, body weakness, more seriously, unconsciousness. It is necessary to notify the doctor immediately for timely treatment when an overdose occurs.

3. Side effects of Spiromide 50/20mg

Side effects of Spironolactone include:
Hyperkalemia, hyponatremia. Big breasts, impotence in men. Menstrual disorders, breast engorgement in women. Voice change in both male and female. Furosemide can cause the following side effects:
Increased blood urea, increased blood uric acid and increased blood sugar levels. Dermatological reactions such as rash, itching, pain, swelling, redness, especially in the face, tongue and throat. Tinnitus, hearing loss, possibly temporary deafness (this is rare). Immediately notify the doctor about the body's reactions when using Spiromide 50/20mg for advice and appropriate dose adjustment.

4. Interaction of Spiromide 50/20mg with other drugs

Concomitant administration of Spiromide 50/20mg with potassium supplements or other potassium containing drugs may cause hyperkalemia. There is a study that shows that Furosemide in Spiromide 50/20mg aggravates systemic lupus erythematosus. Patients who are taking high doses of Salicylate may experience toxicity when used in combination with Spiromide 50/20mg. Spiromide 50/20mg increases the risk of Lithium toxicity by reducing the elimination of Lithium. Concomitant administration of Cephaloridine with Spiromide 50/20 mg increases nephrotoxicity.

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