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Spamorin is a prescription drug, muscle relaxant, muscle tone enhancer, containing the main ingredient is Thiocolchicoside, content of 4mg, prepared as a solution for intramuscular injection, a pharmaceutical product of India. The drug is effective in supporting treatment to reduce muscle spasticity in spinal diseases for people over 16 years old. So what is Spamorin 4mg drug, how to use it, please follow the following article.
1. What is Spamorin?
.Each tube of 2ml of Spamoin solution contains 4mg of the main active ingredient Thiocolchicoside and excipients Sodium chloride, hydrochloric acid, water for injection just enough. The clinical use of Spamorin 4mg is due to the pharmacological effects of the main pharmaceutical ingredient thiocolchicoside. Thiocolchicoside is a semi-synthetic thio-methyl derivative of naturally occurring glycosides and colchicosides. Drugs with muscle relaxants, significantly reducing or drugs associated with muscle spasticity of central nervous system origin. The muscle relaxant effect of the drug is also seen in the internal organs.
Thiocolchicoside acts through the central nervous system, the drug does not cause motor paralysis. The drug has selective affinity for GABA receptors and is a glycinergic agonist. The drug has varying degrees of central nervous system effects, is non-paralytic, is not associated with respiratory problems, and has no effect on the cardiovascular system.
After the injection, about 30 minutes to 40 minutes, the muscle relaxant effect of Spamorin 4mg begins to appear. The half-life of the drug is about 4 hours, the drug is effective for 24 hours. Thiocolchicoside is excreted unchanged in the urine by the kidneys (renal clearance 70 ml/min) and extrarenally when the extrarenal clearance is 200 ml/min. If drug therapy is continued for several days, a cumulative effect is developed, which lasts several days after stopping the drug completely.
2. Indications and contraindications of Spamorin 4mg
Indications:
Spamorin 4mg is indicated for the supportive treatment of symptoms of acute muscle spasticity in spinal diseases such as back pain, low back pain, torticollis... Drugs for people aged 16 years and older. age or older. Do not use Spamorin 4mg in the following cases:
Patients are allergic to thiocolchicoside and excipients. Patients with loss of muscle tone or paralysis, muscle laxity. The patient is taking anticoagulants and has bleeding problems. Do not use Spamorin 4mg in the first trimester of pregnancy and breastfeeding.
3. Dosage and how to use Spamorin 4mg
How to use: Spamorin 4mg is used by intramuscular route.
Dosage:
Usual dose: Intramuscular once a day, a single dose of 4mg/2ml. In case of severe muscle spasticity, the starting dose is 1 ampoule per day (4 mg/2 ml). The recommended course of treatment lasts from 3-5 days. If necessary, the drug can be continued for 5-7 days in oral form, taking 2 tablets (4mg) per day divided equally into 2 times, 1 tablet 4mg each time. When using physical therapy, the time required for effective muscle relaxation is 30 to 40 minutes after the drug is injected intramuscularly.
4. The unwanted effects of the drug Spamorin 4mg
The side effects during the use of Spamorin 4mg as follows:
There may be a rash on the skin because of hypersensitivity to Thiocolchicoside. Rare: After injection, hypotension, euphoria or transient loss of consciousness occur. If the patient experiences any side effects other than the ones mentioned above, notify the treating doctor.
5. Notes in the process of using Spamorin 4mg
The drug is not recommended for use in chronic conditions requiring long-term treatment. Patients who are being treated with systemic thiocolchicoside drugs, if used for a long time, should be reviewed for a more appropriate course of treatment or another treatment method. There are currently no reports of drug interactions with other drugs. However, if used in combination, the patient should be guided by the doctor. There have been no reports of overdoses. If this occurs, the patient should be treated symptomatically with other supportive measures. Do not use Spamorin 4mg in pregnant women, especially in the first 3 months of pregnancy or breast-feeding women, do not use in women of childbearing potential due to not using an appropriate method of contraception. The effect of Spamorin 4mg on the ability to drive or use machines has not been reported. Above is an article about Spamorin 4mg pharmaceutical drug information. The drug is prescribed by a doctor, treating muscle relaxants in case of pathological muscle spasticity in the spine, patients should not use it themselves. If you need more information or have any questions about Spamorin 4mg, please consult your pharmacist/physician.
