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Containing the main drug is Sodium Bicarbonate, Sodium Bicarbonate 1 4 is indicated for use in metabolic acidosis, alkalinization of urine or as an antacid (stomach). However, before using, patients need to know the information about the drug.
1. Uses of Sodium Bicarbonate 1 4
Sodium Bicarbonate 1 4 is essentially an infusion containing sodium, consisting of 7g Bicarbonate and 500ml distilled water for injection. It is indicated in the treatment of metabolic acidosis or urinary alkalinization.
Patients after intravenous infusion of Sodium Bicarbonate, the effect occurs immediately. Treatment of metabolic acidosis should not be too rapid. Therefore, treatment should only be initiated at half the calculated dose and based on blood gas analysis for further treatment.
2. Dosage and usage of Sodium Bicarbonate 1 4
If testing for arterial blood gases (ABGs) is not available, as empiric therapy, administer slowly intravenously at first 1 mEq/kg (1 mmol/kg), after 10 minutes do not exceed 0.5 mEq/ kg (0.5 mmol/kg).
If ABGs are identified, the sodium bicarbonate dose can be calculated based on the alkalinity level as follows:
Sodium bicarbonate dose (mmol) = alkaline deficiency (mmol/l) 0.3 body weight (kg). (Coefficient 0.3 corresponds to extracellular fluid versus whole body fluid).
Correction of metabolic acidosis should not be done too quickly. Therefore, the starting dose should only be 1/2 of the calculated dose. After that, it is necessary to re-test for gas in the blood before continuing treatment.
How to use: Only intravenous infusion at the following rate:
Sodium bicarbonate injection solution 4.2%: Up to 40 drops/minute = 120 ml/hour. Sodium bicarbonate injection solution 7.5% or 8.4%: Approximately 20 - 40 drops/minute = 60 - 120 ml/hour. When infusion of the undiluted high concentration solution, it should be administered only through the catheter into the central vein and preferably into the vena cava.
When infusing children, use 0.5 mEq/ml solution or dilute 1 mEq/ml solution in 1:1 ratio with sterile distilled water.
Note, Sodium Bicarbonate 1 4 is only used when prescribed by a qualified doctor. Self-medication can cause many health and medical problems.
3. Contraindications when using Sodium Bicarbonate 1 4
As recommended by doctors and manufacturers, Sodium Bicarbonate 1 4 infusion solution is contraindicated in cases of respiratory alkalosis and metabolic alkalosis, hypoventilation, and hypernatremia.
Cases such as: heart failure, edema, hypertension, eclampsia, kidney damage also need to be very careful.
Before using Sodium Bicarbonate 1 4, patients also need to discuss with their doctor in detail about all the drugs they are taking, including dietary supplements. Knowing this information makes the dosing process safer.
4. Possible Sodium Bicarbonate 1 4 drug interactions
It is known that sodium bicarbonate is incompatible with many drugs. Therefore, other drugs should not be added to the sodium bicarbonate solution.
Patients should not be infused with sodium bicarbonate, concurrently with solutions containing calcium or magnesium ions.
The use should follow the instructions of the doctor, pharmacist to ensure patient safety.
When using Sodium Bicarbonate 1 4 drugs can cause unwanted reactions, in case of overdose may cause metabolic alkalosis, edema. Therefore, sodium bicarbonate should only be administered intravenously because intravenous injection can cause tissue necrosis.
Besides, in the process of using the infusion solution, attention should also be paid to the possibility of hypokalemia. This is very important for the patient's health.
Hopefully with the sharing of Sodium Bicarbonate 1 4, it will help patients understand and better use it to be able to achieve the highest efficiency in the treatment of disease.
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