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Shuraten is a drug belonging to the group of drugs for osteoarthritis pain, a drug used for long-term oral treatment, especially effective for degenerative joint diseases (osteoarthritis and related diseases).
1. What is Shuraten?
What is Shuraten? Shuraten is made in the form of capsules with the main ingredient Diacerein 50mg. Shuraten is manufactured by Schnell Korea Pharma Co., Ltd - KOREA and circulated on the Vietnamese market with registration number VN-9704-10.
2. The effect of the drug Shuraten
Diacerhein is an anti-osteoarthritis active ingredient with anti-inflammatory effects, commonly used to treat degenerative joint diseases (osteoarthritis and related diseases), this active ingredient is well tolerated in the stomach because the drug is not inhibits prostaglandin synthesis. Diacerein is currently the only drug in the treatment of osteoarthritis with the ability to affect the anabolism and catabolism of chondrocytes and reduce proinflammatory factors. In addition, Diacerein also showed inhibitory effects on macrophage phagocytosis and migration. Studies in several animal models of osteoarthritis have shown a consistent reduction in cartilage degeneration compared with patients not treated with Diacerein.
Clinical studies showed significant pain relief and improved joint function compared with placebo after 1 month of treatment with Diacerein. Other studies have shown that the beneficial effects of this Diacerein treatment persisted for at least 2 months after patients had stopped treatment. A randomized, double-blind, placebo-controlled, 3-year, multicenter study of 507 patients with hip osteoarthritis has shown that Diacerein has the ability to significantly slow degenerative joint disease. cartilage.
3. Indications - contraindications of the drug Shuraten
Oral Shuraten is indicated for the long-term and specific treatment of degenerative joint diseases (osteoarthritis and related diseases).
Shuraten should not be used in patients with known hypersensitivity to the drug/excipients of Shuraten, or contraindicated to use Shuraten in people with a history of hypersensitivity to derivatives of Shuraten. anthraquinones.
4. Dosage and how to take Shuraten
The usual dose of Shuraten is 1 capsule / time, taken 2 times / day. However, because Shuraten can rapidly increase the time it takes for food to pass through the intestines during the first 2 weeks of treatment, most patients should start treatment with a dose of 1 Shuraten capsule/day, taking Shuraten with meals dinner during the first 2 weeks of treatment. Once the patient has become accustomed to Shuraten, the dose should be increased to 2 Shuraten capsules/day. The doctor is the one who will decide the duration of treatment with Shuraten to be effective.
Because Diacerein does not inhibit prostaglandin synthesis, Shuraten is not harmful to the stomach and can be safely prescribed with a nonsteroidal anti-inflammatory drug (NSAID). More specifically, due to the slow onset of action of Shuraten (starting to appear after 2-4 weeks of treatment) and very good tolerability from the gastrointestinal tract, Shuraten can be combined with a non-steroidal anti-inflammatory drug. or pain medication for the first 2-4 weeks of treatment.
5. Be careful when using Shuraten
Caution when using Shuraten in the following cases:
Patients should carefully read the instructions for use before taking Shuraten, if need more information, the patient should consult a doctor; This medicine Shuraten is only used under a doctor's prescription, do not self-medicate without medical guidance; Renal impairment may alter the pharmacokinetics of the active ingredient Diacerein, therefore the dose of Shuraten should be reduced in cases of renal impairment (creatinine clearance <30ml/min); It is not recommended to use laxatives with Shuraten at the same time; Shuraten should not be prescribed to children under 15 years of age, as there are currently no clinical studies of Shuraten in this age group.
6. Interactions of drugs Shuraten
Should avoid concomitant use of Shuraten with drugs containing salts, oxides or hydroxides of aluminum, calcium, magnesium... because they can reduce the absorption of Diacerein. These substances can be taken at a different time (more than 2 hours) after taking Shuraten .
7. Be careful when using Shuraten
Caution should be taken when using Shuraten in the following cases:
Pregnant and lactating women should not use Shuraten, because it has been reported that small amounts of Diacerein derivatives can into breast milk; Effects on driving and using machines: Shuraten does not affect the patient's ability to drive or use machines; Overdose: Taking a high dose of Diacerein by mistake or intentionally can cause diarrhea, at which time the patient should notify the doctor for symptomatic treatment.
8. Undesirable effects of the drug Shuraten
Undesirable effects of the drug Shuraten may occur during use as follows:
Shuraten drug increases the time it takes food to pass through the intestines, abdominal pain is the most common side effect during treatment with the drug. Shuraten . These symptoms may appear within the first few days of treatment with Shuraten and in most cases these symptoms will resolve on their own as the patient continues treatment; Administration of Shuraten can sometimes cause urine to appear darker yellow, which is typical of the class of compounds found in Shuraten and is of no clinical significance. Inform the doctor of any unwanted effects when the patient is taking Shuraten. Shuraten is a drug belonging to the group of drugs for osteoarthritis pain, a drug used for long-term oral treatment, especially effective for degenerative joint diseases. To ensure effective treatment and avoid unwanted side effects, patients need to take the drug exactly as directed by the doctor, absolutely do not buy drugs for home use.
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