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Sildenafil 50mg is a commonly used product in the treatment of impotence, erectile dysfunction in men... So what active ingredients does Shinafil contain and how is it used?
1. Effects of Shinafil 50mg
The main ingredient in the drug Shinafil 50mg is the active ingredient Sildenafil, the content is 50mg and the excipients are just enough. Shinafil medicine is made in the form of tablets, manufactured by Shinpoong Daewoo Pharmaceutical Co., Ltd.
Sildenafil is the main ingredient in the formula of Shinafil. This active ingredient has an inhibitory effect on the enzyme phosphodiesterase, which has the ability to specifically inhibit the cyclic GMP of PDE-5. As a result, the main active ingredient of the drug Shinafil works to help dilate the vascular system in the cavernous body, increasing blood flow to the penis, helping the user's penis become more erect. Shinafil prolongs the relationship time, helping to solve the worry of "not having reached the market and running out of money" of many gentlemen.
In summary, this is the number one preferred solution for men when experiencing erectile dysfunction, need to maintain an erection for long-term relationships and bring better feelings during intercourse. Note that Shinafil only works when there is an accompanying stimulus.
2. Indications to use Shinafil 50mg
Shinafil medicine 50mg is indicated for use in men in the following cases:
Men with pathologies related to sexual function such as impotence, erectile dysfunction, premature ejaculation...; People with hypogonadism, men with menopause;
3. Dosage and usage of the drug Shinafil
3.1. How to take Shinafil tablets are taken orally. Take Shinafil tablets whole with a glass of filtered water, do not crush or break Shinafil tablets because it may affect the bioavailability of the drug. The best time to take Shinafil is 1 hour before sex.
3.2. Dosage of Shinafil drug for adults:
Most patients are recommended to take Shinafil 50mg dose, taken about 1 hour before sex; Based on the tolerability and efficacy of Shinafil, the dose may be increased to a maximum of 100mg or decreased to 25mg. The maximum dose of Shinafil is 100mg, the maximum number of times is 1 time per day. Shinafil dose for patients with renal failure:
Patients with mild or moderate renal impairment (creatinine clearance = 30 - 80mL/min) do not need to adjust the dose of Shinafil; In patients with severe renal impairment (creatinine clearance < 30 mL/min), the dose of Shinafil should be 25 mg, because the clearance of Shinafil is reduced in these patients. Dosage of Shinafil in Hepatic Impairment: The dose of Shinafil should be 25 mg because the clearance of Sildenafil is reduced in these patients (eg, cirrhosis).
The dose of Shinafil for patients who are taking other drugs:
For patients who are taking Ritonavir for treatment, the dose of Shinafil should not exceed a single maximum dose of 25mg within 48 hours; In patients taking drugs that are likely to inhibit CYP3A4 (eg, Erythromycin, Saquinavir, Ketoconazole, Itraconazole), the starting dose of Shinafil should be 25 mg; To minimize the risk of orthostatic hypotension with Shinafil in patients treated with alpha blockers, patients should be stabilized on alpha blocker therapy prior to initiation of Shinafil. In addition, Shinafil should be started at a dose of 25mg. Dosage of Shinafil for children: Do not use Shinafil for children under 18 years of age.
Shinafil dose for the elderly: No need to adjust the dose of Shinafil.
4. Contraindications to the use of Shinafil
Patients with hypersensitivity to the components of the drug Shinafil ; Do not use Shinafil for women; Do not use Shinafil medicine for men under 18 years old; Do not use Shinafil for patients with cardiovascular diseases, blood pressure such as: People with high blood pressure, people with unstable angina; Patients with myocardial infarction, recent stroke; People with hereditary retinal degenerative disorders; Patients being treated with drugs or supplements containing Nitric oxide, organic nitrates: because Sildenafil increases the antihypertensive effect of acute and chronic nitrates.
5. Side effects of the drug Shinafil
Shinafil can cause side effects when used such as:
Flushing, headache; Skin hypersensitivity, allergy, rash; Nausea and vomiting; High blood pressure; Cardiovascular complications such as myocardial infarction, angina pectoris, hypertension; Penile pain, prolonged erection; When you have one of the symptoms caused by a side effect of Shinafil or suspect a side effect, contact your doctor for appropriate treatment.
6. Shinafil drug interactions
Nitroglycerin users should not take Shinafil; Do not use Shinafil for people who are taking alpha sympathomimetic drugs; Close monitoring is recommended if Shinafil is used in patients taking antiretroviral drugs (Saquinavir, Ritonavir); Shinafil medicine may interact with Bosentan, Rifampicin; Shinafil can reduce the elimination of drugs containing active ingredients such as: Erythromycin; Antifungal drugs Itraconazole, Ketoconazole; Cimetidine; Caution should be exercised when these drugs are combined with Shinafil to avoid the risk of toxicity.
7. Notes when using and storing Shinafil medicine
Use Shinafil at the right dose and at the right time according to the prescription; People with problems related to male reproductive function should see a doctor regularly. Be careful when using Shinafil with patients (or have a history of) liver or kidney failure Be careful when prescribing Shinafil to women. have cardiovascular diseases, such as heart attack, history of stroke or congestive heart failure Caution when using Shinafil for sickle cell anemia, leukemia, multiple myeloma...; Pay attention when using Shinafil for people with a history of peptic ulcer disease or retinitis pigmentosa...; Contraindicated to use Shinafil for women, including pregnant and lactating women; Shinafil is only effective when accompanied by sexual stimulation. Store Shinafil medicine out of reach of children, keep it in a cool, dry place, avoid storing it in a place with direct sunlight.
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