This is an automatically translated article.
Savipiride 4 belongs to the group of hormonal drugs (Hormone), with the main ingredient being Glimepiride 40mg. Savipiride 4 is usually prescribed in patients with type 2 diabetes in combination with diet and exercise. Savipiride 4 is not dependent on food, so you can take it at any time of the day.
1. What is Savipiride 4?
Savipiride 4 belongs to the group of hormonal drugs (Hormone), with the main ingredient being Glimepiride 40 mg and excipients just enough for 1 tablet. Savipiride 4 is available in tablet form. Packaging of the drug includes 1 box of 3 blisters, each blister of 10 tablets.
Savipiride 4 is usually indicated in patients with non-insulin dependent type 2 diabetes in combination with diet and exercise. However, Savipiride 4 should not be used in children, pregnant and lactating women, because there are no documents to prove the safety of the drug for this group of people.
2. What does Savipiride 4 do?
Glimepiride is in the drug belongs to the Sulfonylure group, this active ingredient has the ability to lower blood sugar. They stimulate insulin release from the beta cells of the islets of Langerhans of the pancreas. Glimepiride also has extra-pancreatic effects, improving the sensitivity of peripheral tissues to insulin, reducing insulin uptake in the liver, and increasing glucose uptake into muscle and adipose tissue.
Glimepiride is highly bioavailable, so food does not significantly affect the drug. However, drug absorption will be slower. Maximum plasma concentrations of Savipiride 4 are reached 2 to 3 hours after oral administration. The drug is excreted mainly in the urine and faeces, mainly metabolized in the liver. Through numerous animal studies, it has been shown that Savipiride 4 can be excreted in milk and cross the placental barrier of the mother. Therefore, Savipiride 4 should not be used by pregnant or lactating women.
3. Dosage of Savipiride 4
Savipiride 4 is prepared in tablet form, so patients should take it orally. You should take the medicine with a full glass of water, swallow whole, do not chew or crush before taking. Take the medicine once daily with the first meal. The dose of Savipiride 4 will depend on the blood glucose concentration and the patient's tolerance and response to the drug. For those who are new to Savipiride 4, it is advisable to start at the lowest effective dose to bring glucose back to the desired level.
For adults when starting the drug (have not used Savipiride 4 before) should take 1 to 2mg / day. If the patient is in a debilitated state, malnourished, the elderly, kidney failure, liver failure or those at risk of hypoglycemia should take 1mg of the drug per day. For patients who have used Savipiride 4 or antidiabetic drugs before, it is recommended to take 1 to 2 mg/day (no more than 2 mg/day).
For patients using maintenance dose should take from 1 to 4 mg / day. The dose will be gradually increased to match the patient's tolerability and response. The drug should be increased gradually, each increase should not exceed 2mg/day. The maximum dose is 8mg/day. However, if patients using Savipiride 4 8mg/day still cannot control blood sugar levels, it is necessary to combine with insulin to get the best treatment results. When blood glucose levels stabilize, patients still need to monitor their blood sugar daily.
4. Contraindications to the use of Savipiride 4
For some subjects, Savipiride 4 is absolutely not prescribed to avoid unwanted side effects that may affect health, including:
People with hypersensitivity to any ingredient in the drug (Glimepirid) ). Patients with insulin-dependent diabetes mellitus. Patients in a coma, pre-coma, acid-ketogenic due to diabetes. Patients with liver failure, severe renal failure should not use Savipiride 4 but should switch to insulin. People who are pregnant or breastfeeding should not take Savipiride 4.
5. interactions with other drugs
Possible interactions if using Savipiride 4 with the following drugs:
Combining diuretics, Acetazolamide, Phenytoin, Glucagons, Barbiturates with Savipiride 4 will reduce the effect of the drug. Combining Savipiride 4 with oral diabetes drugs, Insulin, Coumarin derivatives, Chloramphenicol, Phenylbutazol, Miconazole will increase the hypoglycemic effect of the drug. Savipiride 4 also alters the effect of the anticoagulant Coumarin.
. What are the possible side effects of Savi Pirate 4 during use?
Side effects may occur with different frequencies in each patient. The appearance of symptoms depends on the patient's condition as well as the extent of the disease. The most undesirable effect that may occur is hypoglycemia. Symptoms appear with more common frequency such as: Dizziness, dizziness, headache, vomiting, nausea, digestive disorders, abdominal and epigastric pain, visual disturbances with new users of the drug.
Precautions while using Savipiride 4
It is necessary to check blood sugar levels on a regular basis to prevent the risk of hypoglycemia and loss of blood sugar control in the body. In some cases, the patient's blood glucose level has stabilized when using drugs and combined with diet, but there may still be a loss of blood sugar control combined with symptoms such as fever, infection, trauma. love. Patients may have allergic reactions such as angioedema, Stevens-Johnson syndrome, hypersensitivity. If one of these symptoms is observed in a patient, the drug should be discontinued immediately. Savipiride 4 should not be used in patients with galactose intolerance or hereditary total lactase deficiency. Savipiride 4 may affect the ability to drive and use machines. Therefore, it is not recommended to perform tasks that require high concentration after using Savipiride 4. Besides, the drug may cause patients to have hemolytic anemia or increase the risk of heart disease. circuit. Savipiride 4 is effective in the treatment of non-insulin dependent type 2 diabetes in combination with diet and exercise. In addition to the therapeutic benefits, the drug can still appear unwanted side effects. Therefore, before using any medicine, you should carefully read the accompanying information and instructions for use of the doctor.
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