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Sagason 75 is a drug belonging to the group of anticoagulants, antiplatelet and fibrinolytic drugs, which are often used in the prevention of thrombosis in diseases such as myocardial infarction, peripheral artery disease,... The following article provides detailed information about the drug Sagason, please read it for reference.1. What is Sagason 75?
Sagason is an anticoagulant, antiplatelet and fibrinolytic drug. Sagason medicine has the main ingredient is Clopidogrel in the form of Clopidogrel bisulfate 75mg. The drug has a content of 75mg each, 1 box has 3 blisters x 10 tablets. Clopidogrel is an inhibitor of platelet aggregation - a stage of blood clotting. It works by inhibiting the Adenosine Diphosphate (ADP) receptor on the surface of platelets and preventing the release of solid granules. ADP-mediated alpha particles, which contain platelet aggregation-promoting substances. Sagason drug is rapidly absorbed from the gastrointestinal tract, maximum drug concentration is reached 1 hour after taking the drug. In the blood about 94 - 98% of the drug is bound to plasma proteins. Sagason drug is metabolised by the liver, excreted in the urine and feces with a half-life of about 8 hours.2. What are the effects of Sagason 75?
Sagason drug is effective in the treatment of the following diseases:Second-line prophylaxis in patients with a recent history of myocardial infarction, stroke or peripheral arterial diseases to reduce the cardiovascular and cerebrovascular events. Used in the treatment of acute coronary syndromes, including unstable angina, myocardial infarction with or without ST elevation. In case of pathology with chronic angina that is intolerant to aspirin. In combination with Aspirin to prevent thrombosis in cases after percutaneous coronary intervention or coronary stenting. In combination with aspirin as an alternative to Warfarin for thromboprophylaxis in patients with atrial fibrillation and/or concomitant cardiac disease. Used in cases where patients with prosthetic heart valves are on antiplatelet therapy who cannot use aspirin. Used as another antiplatelet agent as an alternative to or in combination with aspirin for thromboprophylaxis in patients after coronary artery bypass grafting involving the saphenous vein.
3. Dosage - how to use Sagason 75
How to use: Sagason drug is taken orally, you should take the tablet whole with a glass of water, you can drink it before or after eating as you like because food does not affect the effect of the drug.Dosage: Sagason used as prescribed by the doctor, you can refer to the recommended dose below:
On subjects with a history of atherosclerosis: 75mg/time/day. In the case of thromboembolism prevention such as myocardial infarction, stroke or peripheral arterial disease: 75mg / time / day. In the treatment of acute coronary syndromes such as unstable angina or non-Q-wave myocardial infarction: a single starting dose of 300 mg/day. Then continue to maintain the dose of 75mg/time/day. In case of percutaneous coronary intervention: Use a single starting dose of 600mg/time/day, before or at the time of procedure. Then maintain the dose of 75mg/day. For acute coronary syndrome, the maximum treatment time is 12 months, for coronary artery disease, the minimum treatment time is 12 months. In patients with myocardial infarction with ST elevation, in conservative treatment, a dose of 75 mg/day can be added to aspirin. The duration of treatment is usually less than 28 days. Patients with atrial fibrillation: 75mg/day, can be combined with aspirin. For children under 24 months: Use dose 0.2mg/kg body weight/day. For children over 24 months: The initial dose can be 1mg/kg body weight/day, then adjust the dose according to the child's tolerance. Do not exceed the adult dose. No dose adjustment is necessary in the elderly or in patients with renal impairment.
4. Contraindications to the drug Sagason 75
Do not use Sagason for the following cases:People who are sensitive or allergic to any ingredient of Sagason medicine. Patients are bleeding such as gastrointestinal bleeding, intracranial hemorrhage, ... People with liver failure.
5. Unwanted effects when using Sagason 75
When using Sagason, patients may experience the following undesirable symptoms:The most common are digestive disorders such as: Abdominal pain, constipation, loss of appetite, nausea, ... or allergic reactions. skin reactions such as itching, erythema,... In addition, symptoms such as fatigue, muscle and joint pain, dizziness, headache, angioedema, hypertension, etc. visible: nosebleeds, chest tightness. Rare: Gastrointestinal bleeding, peptic ulcer, severe leukopenia, thrombocytopenia, thrombocytopenic purpura, nephritis,... Other more serious but very rare effects: Internal bleeding skull or bleeding in the eye. Sagason is generally quite safe, but the above adverse symptoms have been noted, so you need to be careful while using the drug, if you experience any side effects, please inform your doctor or staff. nearest you for assistance with symptoms.
6. Note when using Sagason 75
When using Sagason, you need to keep in mind the following points:You need to inform your doctor about the medicines you are using because Sagason drugs may have bad interactions with the drugs you are using, especially drugs with anticoagulant effects such as Heparin, warfarin or aspirin, ... or non-steroidal anti-inflammatory drugs,... Because drugs have antiplatelet effects, affecting blood clotting due to Therefore, special attention should be paid to cases of bleeding due to trauma or surgery because the risk of bleeding is very high. If surgery is required, stop taking Sagason at least 5 days before surgery. You need to inform your doctor about the medical conditions you are suffering from because Sagason can make the disease worse, especially diseases with a high risk of bleeding such as peptic ulcers,... Does not affect the ability to drive and use machines, so you can use the drug if you do this work, but you need to use Sagason medicine as prescribed by your doctor to ensure safety. There have been no studies on the safety of the drug for pregnant women and the development of the fetus, so if you are or are about to become pregnant or may become pregnant, you need to tell your doctor for careful consideration. before deciding on treatment. There are no clear studies on whether Sagason can be excreted in breast milk, so if you are breast-feeding, talk to your doctor to determine the right medicine for you. The above is detailed information about the drug Sagason, if you still have any unclear questions about the drug, you can contact your pharmacist or doctor for support to answer your questions as soon as possible.
