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Rvmoxi drug is used in the treatment of infections caused by bacteria such as acute sinusitis, acute exacerbation of chronic bronchitis, community-acquired pneumonia,... So the use of Rvmoxi drug is what?
1. What is Rvmoxi drug?
Rvmoxi drug belongs to the group of anti-inflammatory, antifungal, antiviral and antiparasitic drugs. Each 100ml of Rvmoxi drug solution contains 400mg of moxifloxacin in the form of moxifloxacin hydrochloride and other active ingredients, excipients are sufficient. Rvmoxi drug is prepared in the form of an infusion solution and packaged in a box of 1 bottle of 100ml.
2. Indications and contraindications
2.1 Indications to use Rvmoxi drug Rvmoxi drug is only in the following cases:
Acute bacterial sinusitis caused by streptococcus pneumoniae, moraxella catarrhalis or haemophilus. Acute exacerbation of chronic bronchitis caused by bacteria streptococcus pneumoniae, haemophilus influenzae, klebsiella pneumoniae, haemophilus parainfluenzae, staphylococcus aureus or moraxella catarrhalis. Community-acquired pneumonia of mild to moderate severity caused by bacteria Mycoplasma pneumoniae, moraxella catarrhalis, chlamydia pneumoniae, streptococcus pneumoniae, haemophilus influenzae,... Besides the above uses, Rvmoxi drug can also be used Treatment of some other medical conditions not listed above. Therefore, before using the drug, consult your doctor for advice and effective use of the drug.
2.2 Contraindication to the use of Rvmoxi The use of Rvmoxi is contraindicated in cases such as:
Patients with hypersensitivity to any ingredient of the drug Children, growing adolescents and pregnant women
3. How to use Rvmoxi
Rvmoxi drug is prepared in the form of solution for infusion and tablets. The recommended dose for Rvmoxi is 1 bottle/bag (400mg/250ml) of infusion or 1 400mg tablet per day. The duration of treatment should be determined according to the severity of the disease or the clinical response. General recommendations for the treatment of upper and lower respiratory tract infections.
For the infusion form, community-acquired pneumonia from 7 to 14 days depends on the clinical response and the severity of the disease. For oral tablets should be swallowed whole with a glass of water can be taken before or after meals. The duration of treatment depends on the condition of the disease. For acute exacerbation of chronic bronchitis, treatment for 5 days, community-acquired pneumonia for 10 days, and acute sinusitis for 7 days. Use Rvmoxi regularly to get the most benefit from it. To use the drug safely, take Rvmoxi exactly as directed by your doctor, do not use more, smaller or longer than prescribed. Absolutely do not arbitrarily increase the dose of the drug or abuse the drug for too long for a long time. This not only makes the condition better, but also increases the risk of unwanted effects.
4. Undesirable effects when using Rvmoxi
Some unwanted effects that may occur when using Rvmoxi include:
Abdominal pain Headache Nausea or vomiting Diarrhea Indigestion Abnormal liver function tests Taste disorders Dizziness Asthenia Fungal infection Candida Back pain, body Allergic reactions Venous system: tachycardia, peripheral angioedema, palpitations, high blood pressure Blood and lymphatic system: leukopenia, eosinophilia, decreased prothrombin, anemia blood, increased or decreased platelets Nervous system: insomnia, restlessness, dizziness, drowsiness, anxiety, paresthesia, depression,... Before prescribing a drug, the doctor always considers the benefits and effects The benefits of Rvmoxi outweigh the risk of side effects. However, some cases when using Rvmoxi can still occur unwanted effects. Therefore, when unusual symptoms occur, especially when a severe allergic reaction occurs with accompanying signs such as difficulty breathing, severe dizziness, rash, swelling or itching of the face, throat, tongue,... In this case, the patient should immediately notify the medical staff for immediate intervention.
5. Some notes when using Rvmoxi
Some notes when using Rvmoxi medicine include:
Inform your doctor about a history of allergy to Rvmoxi or any other allergies. Rvmoxi may contain ingredients that don't work and could cause an allergic reaction or other serious problems. Report any medications you are taking including prescription and nonprescription drugs, herbs and supplements, foods, dyes or preservatives. Rvmoxi, as well as some other quinolones and macrolides, may prolong the QTc interval. Although the degree of QTc prolongation is small (1.2%), Rvmoxi should be used with caution in patients with congenital or acquired long QTc syndrome or in patients receiving drugs with the potential to prolong QTc. QTc interval (eg, class Ia and III antiarrhythmics). Tendonitis and tendon rupture may occur during treatment with quinolones, especially in elderly patients and those receiving corticosteroids. At the first signs of pain or inflammation, the patient should be discontinued and the affected limb immobilized. Tendon ruptures have not been reported in clinical studies with Rvmoxi. Pseudomembranous colitis has been reported with the use of broad-spectrum antibiotics. Therefore, it is important to consider this diagnosis in patients who develop severe diarrhea while taking antibiotics. In this situation, appropriate treatment measures should be taken. No cases of pseudomembranous colitis have been reported in clinical studies. Seizures may occur during treatment with quinolones. Rvmoxi should be used with caution in patients with known or suspected CNS diseases that may precipitate seizures or lower the seizure threshold. Pregnant and lactating women should not use Rvmoxi, because there is clinical evidence that small amounts of Rvmoxi can be excreted in breast milk. Take the missed dose as soon as possible. However, if the time you remember is close to the time of your next dose, skip the missed dose and continue taking the medicine as scheduled. Do not arbitrarily add more than double the dose of the drug than the treatment regimen. Using an overdose of Rvmoxi medicine can cause serious symptoms such as nausea, vomiting, abdominal pain, weakness,...
6. Drug interactions
Drug interactions can reduce the effect of Rvmoxi, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including vitamins, over-the-counter medicines, prescription drugs, and herbal products. Do not stop, start, or change the dose of any medicine without your doctor's consent without your doctor's consent.
Some drugs that may interact with Rvmoxi include:
Food and dairy products: The absorption of moxifloxacin is not changed when taken with food. Therefore, moxifloxacin can be taken regardless of meals. Ranitidine: Concomitant use of ranitidine did not significantly alter the absorption of moxifloxacin. The absorption parameters (Cmax, tmax, AUC) were very similar, indicating that gastric pH had no effect on gastrointestinal absorption of moxifloxacin. Antacids, Minerals and Multivitamins: Co-administration of moxifloxacin with antacids, minerals and multivitamins may decrease drug absorption by forming chelated complexes with polyvalent cations present in the drug. these preparations. This may cause plasma concentrations to be significantly lower than desired. Therefore, antacids, antiretrovirals and other preparations containing magnesium, aluminum and other minerals such as iron should be taken at least 4 hours before or 2 hours after taking moxifloxacin. Warfarin: No drug interactions have been observed during concomitant treatment with warfarin on prothrombin time and other coagulation parameters. Digoxin: The pharmacokinetics of digoxin are not significantly affected by moxifloxacin (and vice versa). Theophylline: Moxifloxacin has no effect on the steady-state (and vice versa) theophylline pharmacokinetics, indicating that moxifloxacin does not affect the 1A2 subtype of cytochrome P450 enzymes; theophylline concentrations did not increase at steady state during combination therapy with moxifloxacin (Cmax 10.5 vs 10.1mg/l, without and with theophylline). Therefore, no dose adjustment of theophylline is required. Probenecid: In a clinical study investigating the effect of probenecid on renal excretion, there was no significant effect on the systemic and renal clearance of moxifloxacin. Therefore, no dose adjustment is required when the two drugs are used concurrently. Diabetes Drugs: There are no clinically important drug interactions between glibenclamide and moxifloxacin. Photosensitivity: Phototoxicity has been reported with other quinolones. However, a study in human volunteers concluded that moxifloxacin had no potential for phototoxicity.
7. How to store Rvmoxi
Store Rvmoxi at room temperature, away from light and away from moisture. Do not store Rvmoxi in a humid place or in the freezer. Different medicines will have different storage methods, so read carefully the storage instructions for Rvmoxi medicine on the package, or ask your pharmacist. Keep Rvmoxi medicine out of the reach of children and family pets. When the medicine has been damaged, it cannot be used anymore or has expired, please dispose of the medicine according to the correct procedure. Do not arbitrarily dispose of Rvmoxi medicine into the environment such as water pipes or toilets unless requested. Please consult your waste management company or pharmacist on how to safely dispose of Rvmoxi to help protect the environment.
In summary, Rvmoxi drug is effective in the treatment of bacterial infections such as acute sinusitis, acute exacerbation of chronic bronchitis, community-acquired pneumonia,... However, Rvmoxi can cause some unwanted effects and drug interactions, so tell your doctor what medicines you are taking to reduce the risk of side effects and at the same time increase the effectiveness of the process. treatment.
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