This is an automatically translated article.
Rovas 3M is indicated in cases of infections in the respiratory tract, skin and genitals caused by bacteria sensitive to the drug; Prophylactic treatment of meningococcal meningitis when rifampicin is contraindicated; Prophylaxis of congenital Toxoplasma infection in pregnancy and prevention of recurrent acute rheumatic fever.
1. What is Rovas 3M?
Rovas 3M is an antibiotic of the Macrolide group, made in the form of film-coated tablets with the following ingredients:
Active ingredient Spiramycin with a content of ~ 3,000,000 IU. Excipients are just enough for 1 tablet: Aerosil, tapioca starch, talc, magnesium stearate, sodium starch glycolate, titanium dioxide, HPMC, PEG 6000. At serum concentrations, Rovas 3M has a bacteriostatic effect. . However, when reaching concentrations in tissues, the drug will kill bacteria. The drug works by acting on the 50S subunit of the bacterial ribosome. This prevents bacteria from synthesizing proteins.
Bacterial strains that Rovas 3M drug works on are:
Gram-positive bacteria. Coccus strains such as Staphylococcus, Pneumococcus, Meningococcus.
2. Indications to use Rovas 3M
Rovas 3M is indicated in the following cases:
Treatment of infections of the respiratory tract, skin and genitals caused by bacteria sensitive to the drug. Indications for the prophylaxis of meningococcal meningitis when rifampicin is contraindicated. Prophylaxis of congenital Toxoplasma infection during pregnancy. Prevention of recurrent acute rheumatic fever in patients allergic to penicillin.
3. How to use, dosage of Rovas 3M
How to take Rovas 3M:
Food in the stomach will reduce the bioavailability of Rovas 3M, so it should be taken at least 2 hours before meals or 3 hours after meals. Patients using Rovas 3M must follow the entire course of treatment. Dosage of Rovas 3M:
Treatment dose:
Adults and children over 12 years old use a dose of 3,000,000 IU, 3 times in 24 hours (1 tablet x 3 times/day). Children take 150,000 IU/kg body weight/24 hours, divided into 3 times. Prophylactic treatment of meningitis caused by Meningococcus strains with Rovas 3M:
Adults and children over 12 years old: Take 3,000,000 IU Rovas 3M, every 12 hours (1 tablet x 2 times/day). Prevention of congenital Toxoplasma infection in pregnancy:
Take 9,000,000 IU/day (3 tablets/day), divided into several times. Take for 3 weeks, every 2 weeks for a booster dose. The above treatment dose is for reference only. The specific dose you will need will depend on your condition and disease progression. Therefore, you need to consult your doctor or pharmacist.
4. Side effects of Rovas 3M
Common side effects:
Digestive system: Nausea and vomiting, diarrhea or indigestion. Uncommon side effects:
Whole body: The patient will feel tired, nosebleed, sweat a lot or feel chest pressure. Temporary paresthesias, dysesthesias, unsteadiness, myalgia and joint stiffness, burning sensation at the injection site (intravenous administration). Gastrointestinal: Acute colitis. Skin: Skin rash, urticaria. Rare side effects:
Anaphylaxis, superinfection due to long-term drug use. When you experience side effects of Rovas 3M, you need to stop using it and notify your doctor or go to the nearest medical facility for timely treatment.
5. Notes when using Rovas 3M
When using Rovas 3M, you should note:
Rovas 3M is contraindicated for people with a history of hypersensitivity or allergy to Spiramycin and Erythromycin. Use caution when administering Rovas 3M to patients with liver dysfunction. Rarely, Rovas 3M has an effect on the ability to drive and use machines. Rovas 3M crosses the placenta, but concentrations are lower in the mother's blood. Therefore, the drug does not cause complications when used for pregnant women. Spiramycin is excreted in human milk in high concentrations. Breastfeeding should be discontinued while taking the drug. Concomitant use of Rovas 3M with oral contraceptives makes the contraceptive ineffective. Above is information about uses, dosage and precautions when using Rovas 3M medicine. You need to strictly follow the instructions on dosage and use to promote the effectiveness of treatment and ensure safety when using the drug. If any unusual symptoms appear after taking the drug, take the patient to the nearest medical center for timely treatment.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
