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Ronasdo belongs to the group of gastrointestinal drugs, with the main active ingredient being Esomeprazole 20mg or Esomeprazole 40mg. Ronasdo is used in the treatment of gastroesophageal reflux disease. Dosage, usage as well as usage notes are important things that the following article will provide readers.1. What is Ronasdo?
Gastroesophageal reflux is a phenomenon in which stomach contents and fluids back up into the esophagus causing discomfort to the patient. Ronasdo is used to treat reflux. With the main ingredient is Esomeprazole , Ronasdo drug is prepared in the form of enteric-coated film-coated tablets with rapid effect on gastroesophageal reflux disease, peptic ulcer patients.
Packing: Blister includes 7 enteric coated film-coated tablets, a medicine box includes 2 blisters.
2. Uses of the drug Ronasdo
Ronasdo drug with the main ingredient Esomeprazole is used in the treatment of gastroesophageal reflux disease (GERD). In addition to the above effects, Ronasdo can also be used in combination in healing duodenal ulcers infected with Helicobacter Pylori and preventing gastric ulcers in patients with pre-existing diseases.
Esomeprazole is an S-isomer of Omeprazole. Esomeprazole is a relatively weak alkali, which is concentrated and converted to an active substance in the acidic environment of the parietal cells of the stomach. With its modified form, Esomeprazole induces inhibition of the enzyme H+K+-ATPase (acid pump enzyme) and inhibits basal or excitatory secretion of gastric parietal cells.
The effectiveness of Ronasdo is effectively tested when the patient after 5 days of taking the drug shows that the pH in the stomach is > 4, which indicates that the amount of acid in the stomach has decreased sharply. The drug Ronasdo can be maintained for a period of 13-17 hours within 24 hours before the patient with gastroesophageal reflux shows symptoms of reflux.
Ronasdo is well absorbed from the gastrointestinal tract and 80% of the drug is excreted in the urine as metabolites, the rest is excreted in the feces.
3. Indications for taking Ronasdo
With the main use of preventing the secretion of acid and gastric juice in the parietal cells of the stomach, Ronasdo is indicated in the following cases:
Treatment of gastroesophageal reflux disease (GERD). Inflammation of the esophagus due to repeated reflux. Long-term prophylactic treatment for patients with esophagitis who have recovered. Cure duodenal ulcers infected with Helicobacter Pylori by combining with a reasonable antibacterial regimen. Treatment of stomach ulcers for patients taking NSAIDs. Prophylaxis of gastric ulcers in patients taking NSAIDs. Prophylactic treatment of peptic ulcer rebleeding (previous treatment of peptic ulcer by intravenous infusion). People with Zollinger Ellison syndrome.
4. Contraindications to taking Ronasdo 20
Do not use Ronasdo 20 in patients with hypersensitivity to Esomeprazole, Benzimidazole subclass or any of the ingredients in the excipients of Ronasdo 20.
5. Dosage and how to use Ronasdo 20
Ronasdo drug is prepared in the form of film-coated tablets that dissolve in the intestines, the patient needs to take the drug with a full glass of water.
Basic dosage:
Dosage in duodenal ulcer disease: Ronasdo 20 mg/day, used continuously for 2-4 weeks. Dosage in the treatment of gastroesophageal reflux disease with gastric ulcer: Ronasdo 20 mg/day, used continuously for 4-8 weeks. At baseline, concentrations may be increased to 40 mg/day Ronasdo if the patient is resistant to other previous therapies.
Treatment of Zollinger Ellison syndrome: 60mg/day, the duration of use as prescribed by the doctor. Prophylaxis of recurrent gastric ulcer - duodenal ulcer: Dose 20-40mg/day, duration of use as prescribed by the doctor.
6. Ronasdo 20 . drug side effects
Possible side effects when using Ronasdo 20 include:
Common side effects:
Whole body feeling tired, headache. Diarrhea, feeling bloated, constipation, nausea. Ronasdo 20 side effects are uncommon and rare:
Dermatitis, urticaria, itching, dizziness, dry mouth. Angioedema, anaphylactic reaction. Increase liver enzymes. As an isomer of Omeprazole, Esomeprazole in Ronasdo 20 can also cause the following side effects in users
Paresthesias, somnolence, insomnia, reversible mental confusion, agitation, in In severe cases, hallucinations can occur. Gynecomastia (gynecomastia in men) Leukopenia, thrombocytopenia, hypovolemia. Hepatitis, jaundice due to liver failure Joint pain, muscle weakness. Alopecia, epidermal necrolysis, photosensitivity.
7. Note when using Ronasdo 20
Care should be taken when using Ronasdo 20 in pregnant or lactating women. Above all, malignancy should be ruled out if peptic ulcer disease is suspected. When using Esomeprazole for long-term treatment, it may increase the risk of atrophic gastritis, increase the risk of pneumonia, increase the risk of diarrhea caused by Clostridium difficile. Dosage Ronasdo 20 is very important in the treatment of gastric ulcers, gastroesophageal reflux disease as well as side effects. Therefore, it is necessary to follow the dose prescribed by the doctor, avoid taking too much, underdosing. Ronasdo is a drug that reduces the secretion of acid and gastric juice in the parietal cells of the stomach. The drug is prescribed in the treatment of gastroesophageal reflux disease and supports the treatment of peptic ulcer disease, patients absolutely do not use it without a doctor's prescription.
