This is an automatically translated article.
Romidepsin is an anti-cancer drug, which works to stop cancer cells from growing. It is used primarily in the treatment of cutaneous T-cell lymphomas and peripheral T-cell lymphomas with at least 1 prior systemic therapy.
1. What are the uses of Romidepsin?
Romidepsin is used in the treatment of cutaneous T-cell lymphoma and peripheral T-cell lymphoma with at least 1 prior systemic therapy. Romidepsin is used to stop cancer cells from growing. In addition, some other effects of the drug are not listed but can be prescribed by your doctor in treatment.2. Dosage of Romidepsin
Usual Adult Dose for Peripheral and Peripheral T-cell Lymphoma: Romidepsin 14mg/m2 IV over 4 hours on days 1, 8, and 15 of a 28-day treatment cycle, repeat the cycle period for people with a good response to treatment.
Dosage of Romidepsin for children: A specific dose should be prescribed by a doctor based on the child's condition and medical condition.
3. How to take Romidepsin
Romidepsin drug mixed with solvent and injected slowly into the vein over 4 hours, 3 times / month, 1 time a week, and 1 week of rest between treatments. Dosage depends on the patient's condition, weight, and response to the drug.
4. Romidepsin side effects
Nausea, vomiting, fatigue, loss of appetite are common side effects during treatment, at least one of these symptoms persists or is more severe.
In addition, the drug also causes bone marrow failure leading to a decrease in red blood cells, white blood cells and platelets. This leads to anemia, decreased immune system, bruising, easy bleeding. These side effects may persist during treatment and persist for up to 30 days after treatment ends.
Side effects are unavoidable during cancer treatment, often, doctors still prescribe them because they judge the benefits of the drug to outweigh the side effects. Instead, the focus will be on close monitoring to detect side effects early and find ways to limit them.
5. Note when using Romidepsin
Be careful when using drugs for subjects allergic to drug ingredients; liver, cardiovascular and infectious diseases. Absolutely do not use stimulants such as alcohol, tobacco during the treatment
Romidepsin can cause QT prolongation, rapid heartbeat along with dizziness, fainting. Therefore, before using the drug, you will be asked about heart conditions such as heart failure, bradycardia, family history of cardiovascular disease.
Low blood potassium and magnesium increase the risk of QT prolongation that often occurs with diuretics. You need to make sure to provide enough information about the medications you are taking to get treatment advice from your doctor.
Romidepsin may worsen existing infections. Therefore, during treatment, it is necessary to wash hands thoroughly, limit contact with infected people.
The drug is not used for pregnant women because of the risk of affecting the fetus. The drug is also not used for women who are breastfeeding because of the risk of affecting infants and young children.
The above sharing about Romidepsin medicine cannot replace the advice of a doctor. Therefore, in the process of using the patient, it is necessary to strictly follow the instructions to ensure the effectiveness of the treatment.
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