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Ribazole 200mg is indicated for the treatment of viral hepatitis HAV, HBV, HCV, Herpes Zoster, Herpes Labialis, Herpes Genitalis and influenza,... In addition to Ribazole 200mg, the drug also has large concentrations such as Ribazole 400mg and Ribazole. 500mg. So how effective is Ribazole? Notes when using Ribazole will be shared through the article below
1. What is Ribazole Capsule?
Ribazole Capsule is a group of drugs that treat parasites, infections, viruses, and fungi. The drug has the main ingredient as the active ingredient Ribavirin with a concentration of 200mg and other excipients such as: Microcrystallin cellulose, Talc, Magnesium stearate, empty Gelatin capsule No. and opaque body, the tablet has the Getz logo printed on it and 200mg contains a white powder. The drug is packaged in a box of 2 blisters x 5 tablets.
2. Effects - Indications of Ribazole 200mg
2.1. The effect of the drug Has the ability to fight viruses in a broad spectrum, with little toxicity. Ribavirin has a similar structure to Guanosin, a nucleoside that makes up RNA, competes for the binding site of guanosin to prevent viral RNA synthesis, thereby inhibiting viral replication without affecting the function of cells. normal cells.
2.2. Indications of the drug Treating patients with HCV, HAV, and HBV viral hepatitis. Treatment for patients with Herpes Labialis, Herpes Zoster, Herpes Genitalis. Treatment of patients with influenza (except influenza B), helping to reduce the severity of illness and shorten the duration of treatment. Treatment for children with some other viral diseases: chickenpox, measles, mumps, respiratory syncytial virus and some other diseases. Hepatitis A, B, C caused by viruses, Herpes zoster, herpes simplex. Shorten the duration of the flu. Common viral diseases in children: Chickenpox, measles, mumps, respiratory syncytial.
3. Usage - Dosage of Ribazole 200mg
3.1. Dosage of the drug The dose of Ribazole Capsules depends on the weight of the patient, the type of virus Genotype and the indication for drug combination in each patient.
The usual dose for people < 75kg is 1000mg corresponding to 5 x 200mg (2 tablets in the morning and 3 in the afternoon). Prolonged treatment of Ribazole Capsules from 1⁄2 to 1 year. Patients > 75kg is 1200mg, respectively 6 x 200mg (3 tablets in the morning and 3 in the afternoon). Prolonged treatment of Ribazole Capsules from 1⁄2 to 1 year. Patients with HAV: Use 3 times a day, each time 400mg Ribavirin. Treatment lasts from 10-14 days. Herpes patients: Use 3 times a day, each time 400mg Ribavirin. Treatment lasts 7-10 days. Patients to prevent recurrence of Herpes Genitalis: Take the drug once a day, take 400mg of Ribavirin. Treatment lasts 1⁄2 - 1 year. Adults: Hepatitis A 800mg Ribavirin/day, divided into several times x 10-14 days. Hepatitis B & C 800 - 1200 mg Ribavirin/day, divided 3 - 4 times x 6 months - 1 year. Herpes zoster/simplex 800 - 1200 mg Ribavirin/day, divided into 3 - 4 times x 7-10 days. Prevention of recurrence of genital herpes 400mg Ribavirin/day, divided into 1-2 times x 6 months. 3.2. Ribazole 200mg drug is made in the form of film-coated tablets, so patients use the drug orally, it should be taken twice a day with food (morning and afternoon). Take Ribazole with filtered or boiled water, do not chew the tablet, swallow it whole.
4. Contraindications to using Ribazole 200mg
Ribazole 200mg should not be used in the following cases:
Patients with a history of hypersensitivity or allergy to Ribavirin or to any of the excipients in the drug. Ribazole should not be used by pregnant and lactating women, including those suspected of being pregnant. The patient had a history of severe heart disease prior to taking the drug, including unstable and uncontrolled heart disease within the previous 6 months. Patients with blood disorders such as sickle cell anemia, Mediterranean anemia - Thalassemia . Children under 6 years old. Patients with a history of asthma, Glaucoma, respiratory failure, impaired liver and kidney function, bladder neck obstruction, cardiovascular disease, prostate enlargement. The patient is taking MAOIs. Patients with severe renal failure (ClCr < 30ml/min). Chronic anemia (Hb < 10g/dl).
5. Side effects when taking Ribazole 200mg
Besides the effects of the drug, patients treated with Ribazole 200mg may also experience some unwanted effects such as:
Heart disorders: Palpitations, peripheral edema, tachycardia, myocardial infarction, congestive heart failure, atrial fibrillation, pericarditis, angina, supraventricular tachycardia Respiratory, thoracic and mediastinal disorders: Dyspnea, epistaxis, cough, nasopharyngitis , nasal congestion, rhinitis, sinus congestion, sore throat, wheezing, fatal interstitial lung disease, pulmonary embolism. Digestive disorders: Diarrhea, vomiting, nausea, abdominal pain, dysphagia, stomatitis, flatulence, constipation, dry mouth, gastric bleeding, cheilitis, gingivitis, gastric ulcer, gland inflammation pancreatitis, ulcerative colitis, pale tongue, ischemic colitis. Skin and subcutaneous soft tissue disorders: Dermatitis, alopecia, pruritus, dry skin, rash, increased sweating, eczema, psoriasis, urticaria, skin disorders, photosensitivity reactions, Night sweats, toxic epidermal syndrome, Stevens Johnson syndrome, erythema multiforme, angioedema. Bone and connective tissue disorders: Arthralgia, myalgia, back pain, arthritis, muscle weakness, erection pain, cramps, musculoskeletal pain, myositis, rhabdomyolysis. Body as a Whole: Shiver, fever, pain, weakness, fatigue, irritability, chest pain, flu-like illness, malaise, lethargy, hot flashes, thirst, weight loss. Bacterial and parasitic infections: Upper and lower respiratory tract infections, bronchitis, Herpes simplex disease, oral candidiasis, pneumonia, urinary tract infections, skin infections, endocarditis, otitis externa. Blood and Lymphatic System Disorders: Anemia, neutropenia, thrombocytopenia, lymphadenopathy, pancytopenia, non-regenerative anemia. Immune system disorders: Thyroiditis, granulomatous disease, anaphylaxis, systemic lupus erythematosus, rheumatoid arthritis, idiopathic thrombocytopenia,...
6. Drug Interactions Ribazole Capsules 200mg
When using Ribazole Capsules systemically, there is a synergy between Ribavinn and Dideoxyinosine (long term) in HIV suppression.
To ensure safety, please list to your doctor, pharmacist all drugs or pharmaceuticals you are using to avoid possible bad interactions.
7. Notes when using and storing Ribazole
Consider this drug when treating patients with symptoms of diffuse cirrhosis, patients with impaired renal function.
Patients need to strictly adhere to the prescribed dose of Ribazole, do not adjust the dose arbitrarily, leading to an overdose or under-dosage that affects the effect of the drug.
Read the instructions for use carefully before taking Ribazole.
Use caution when using Ribazole for pregnant women and women who are breastfeeding.
Store Ribazole 200mg in a cool dry place, avoid humid places or direct sunlight, the preferred temperature is from 25 - 30 degrees Celsius.
Ribazole does not adversely affect the ability to drive and operate machinery. . However, Pegimterferon alfa or interferon alfa when used in combination with Ribazole may be affected.
Hopefully with the information provided above, patients can have more useful information about Ribazole 200mg. Patients should always strictly follow the medication instructions and instructions from the doctor, pharmacist before using Ribazole 200mg, absolutely do not buy the drug at home and self-treat it will cause side effects. Women do not want to affect their health.
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