This is an automatically translated article.
Radaugyl belongs to the group of anti-bacterial, anti-viral, anti-fungal drugs with the main ingredients Spiramycin and Metronidazole. It is often used to treat oral infections, gingivitis, periodontitis, or to prevent oral infections after surgery.1. What does Radaugyl do?
Radaugyl drug has the main ingredients Spiramycin and Metronidazol with the following specific effects:
Spiramycin is a Macrolide antibiotic with a broad antibacterial spectrum and stronger potency than Erythromycin. The drug has a bacteriostatic effect on bacteria that are dividing cells by preventing the bacteria from synthesizing proteins. At high concentrations the drug can have a bactericidal effect. Metronidazole is an antibacterial drug of the nitro-5 - imidazole family that has good activity against both acute and chronic intestinal amoeba and extraintestinal amoeba. The drug's mechanism of action is to be reduced by electron transport proteins or by ferredoxin to lose the DNA helix structure, destroy bacteria and protozoa Radaugyl is usually indicated in the following cases:
Acute oral infections , chronic or recurrent such as tooth abscess, inflammation, cellulitis around the jawbone, periodontitis, gingivitis, periodontitis, stomatitis, parotid gland inflammation, submandibular inflammation, ... Prevention of dental infections after surgery Contraindications of Radaugyl include:
Patients with hypersensitivity to Metronidazole, Imidazol derivatives or Acetyl spiramycin. Women who are breastfeeding
2. Dosage of Radaugyl drug:
Depending on the subject and treatment goal, the dose of Radaugyl will be different, specifically as follows:
Adults: 4-6 tablets/day, divided 2-3 times Children 10-15 years old: 1 tablets x 3 times/day Children 5-10 years old: 1 tablet x 2 times/day When overdosing Radaugyl can cause manifestations of nausea, vomiting, ataxia, convulsions, peripheral neuritis. Currently there is no specific antidote, mainly symptomatic and supportive treatment.
3. Side effects of the drug Radaugyl
In some patients when using Radaugyl, side effects may occur such as:
Digestive disorders: Stomach pain, nausea, vomiting, diarrhea. Allergic reactions: urticaria. Glossitis, stomatitis. Moderate leukopenia is reversible upon discontinuation of the drug. Rare: dizziness, loss of coordination, ataxia, paresthesia, sensory and motor polyneuritis. Urine is reddish brown.
4. Precautions when using Radaugyl:
Some general notes when using Radaugyl include:
Caution when using Radaugyl for patients with suspected gastric ulcer, ileocecal inflammation or chronic colitis. Because it is prepared in the form of film-coated tablets, the release is slow in the body, so it can be toxic to the elderly or people with slow bowel movements. Note that Radaugyl should not be used while lying down. Research shows that pregnant women using Metronidazol in the first 3 months do not cause malformations, spiramycin crosses the placenta, but the concentration of the drug in the placental blood is lower than in the mother's blood, causing no complications for the pregnant woman.
5. Drug interactions with Radaugyl
Acetyl spiramycin should not be used together with oral contraceptives because it can make the contraceptive ineffective. When metronidazole is used concurrently with Disulfiram can cause neurotoxicity such as psychosis, confusion. Metronidazole may increase the toxicity of oral anticoagulants (Warfarin) and increase the risk of bleeding due to reduced hepatic catabolism. Therefore, when used in combination, it is necessary to regularly check the prothrombin level, adjust the dose of the drug. Antifreeze . Metronidazole increases the effect of Vecuronium (muscle relaxant) when taken together. Increases the concentration of Lithium in the blood, causing toxicity when used concurrently. Increased toxicity of Fluorouracil by reducing clearance. When used in combination with alcohol causes Antabuse effect (heat, vomiting, heart palpitations). Above is information about uses, dosage and precautions when using Radaugyl medicine. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Radaugyl exactly as directed by your doctor.
