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Rabupin 20 is a drug commonly used in prescribing for the treatment of diseases of the gastrointestinal tract, especially diseases related to the stomach and duodenum. So what is Rabupin 20? What are the uses of Rabupin 20 and how to use it effectively and safely for patients?
1. What is Rabupin 20?
Rabupin 20 is a drug belonging to the group of gastrointestinal drugs.
The main ingredient of the drug is Rabeprazole sodium 20mg.
Rabeprazole sodium belongs to the group of proton pump inhibitors, has the ability to strongly inhibit H +, K + and ATPase prepared from the stomach lining of pigs. Rabeprazole has 2 main uses: inhibiting gastric acid secretion and preventing peptic ulcers.
About the ability to inhibit gastric acid secretion:
Rabeprazole sodium stimulates the Dibutyl cyclic AMP in the gastric gland through which to inhibit gastric acid secretion. On the other hand, Rabupin 20 also inhibits gastric acid secretion through the mechanism of stimulation of histamine or pentagastrin. Compared with other proton pump inhibitors, rabeprazole has a faster reversal of antisecretory activity and a lower effect on increasing blood gastrin concentrations. Regarding the effect related to the anti-ulcer activity of Rabeprazole: in an experiment conducted on rats, it was shown that Rabeprazole has a strong anti-ulcer effect on many different types of ulcers, while also improving the mucosal lesions well. gastric mucosa.
2. Uses of Rabupin-20
Rabupin 20 has a very good use in preventing, treating and healing lesions in the stomach and duodenum. The drug effectively improves the symptoms of peptic ulcer disease after 4 to 8 weeks of treatment.
Indications to use Rabupin 20 in the following cases:
Patients with peptic ulcer. Reflux esophagitis. Treatment of Zollinger-Ellison syndrome (Stomach acid hypersecretion syndrome). The drug has a good effect in supporting the treatment of duodenal ulcers that test positive for H-pylori bacteria. Contraindications for use in patients:
There is a history of allergy or hypersensitivity to any of the components of the drug. Pregnant and lactating women.
3. Dosage and how to use Rabupin 20
Currently the drug is produced in the form of enteric coated tablets, boxed with 3 blisters, each blister contains 10 tablets.
Dosage:
For adults: 10mg/day. Depending on the severity of the disease, the dose can be adjusted up or down, up to 20mg/day. The duration of treatment for duodenal ulcer is 4 to 8 weeks, while for reflux esophagitis and peptic ulcer, it is necessary to take the drug for about 6 to 12 weeks. Currently, there are no research documents confirming the safety of the drug in children, so it is not recommended to use the drug in children.
4. Side effects of Rabupin 20
Unwanted effects may occur in patients using Rabupin 20 such as:
Urticaria, allergic rash. Causing digestive disorders leading to constipation or diarrhea depending on the patient's location, abdominal heaviness, bloating. Some people get headaches after taking the medicine. Affects liver function. In addition, because the main ingredient contains Rabeprazole, you may experience some other side effects related to this active ingredient, including:
Asthenia, fatigue, poor appetite, loss of appetite, black stools. Allergic reactions, fever, feeling of dry mouth, belching. Chest pain under the sternum, increased sensitivity to light. Few people have mouth ulcers, cholecystitis, colitis, pancreatitis or glossitis, esophagitis...
5. Notes when using Rabupin 20
To be safe and limit the side effects when using Rabupin 20, it is necessary to note the following:
Use the drug according to the instructions and instructions of the doctor, do not arbitrarily adjust the dose of the drug. Note the expiry date of the medicine, do not use the medicine after the expiry date. Before administering the drug, the possibility of malignancy related to peptic ulcer disease should be excluded. Concomitant use of Rabupin 20 with Digoxin will increase the concentration of Digoxin in the blood, which may affect health, so it should be noted when prescribing to patients. Use with caution in patients with liver or kidney failure. If the patient has a history of cirrhosis but requires medication, consult a doctor before use, consider reducing the dose. Do not use the drug on women who are pregnant or breast-feeding. Keep medicine out of reach of children. Store the medicine according to the manufacturer's instructions, avoid direct sunlight. Rabupin 20 is not the only drug that contains the ingredient Rabeprazole, currently on the market there are many other brand names that also have this active ingredient. Each drug will contain different concentrations combined with different excipients and are suitable for different medical conditions. Therefore, arbitrarily choosing to use drugs may not bring about effective treatment, and cause side effects affecting the patient's health. Please contact specialist doctors for advice and prescribe the most appropriate, safe and effective treatment.
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