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Drug Pyme Cinazin belongs to the group of H1 antihistamines. It is used to treat symptoms caused by vestibular disorders, peripheral circulation disorders and cerebrovascular problems, and to prevent motion sickness. The notes and how to use Pyme Cinazin effectively will be shared in the article below.
1. What is Pyme Cinazin?
Pyme Cinazin medicine has the main ingredient Cinnarizine, effective in treating symptoms of vestibular disorders, cerebrovascular diseases, preventing symptoms of motion sickness, seasickness. It is an H1 antihistamine with anti-acetylcholine and sedative effects.
Cinnarizine ingredient in Pyme Cinazin reduces smooth muscle contractions caused by various vasoactive agents (histamine, angiotensin, bradykinin, nicotine, acetylcholine, adrenaline, noradrenaline, BaCl2).
Pyme Cinazin induces smooth muscle contraction by selectively inhibiting the influx of calcium ions into depolarized cells thereby reducing the amount of calcium ions required for muscle contraction. Cinnarizine is not toxic and does not interfere with important physiological functions of the central nervous system, does not affect circulatory and respiratory functions.
Pyme Cinazin extensive metabolism in the liver occurs within 1⁄2 hours after oral administration. Metabolites are excreted in feces and urine (2⁄3 in feces; 1⁄3 in urine). The drug is completely eliminated within 5 days after stopping the drug.
2. Indications of Pyme Cinazin
Maintenance treatment of vestibular disorders, accompanied by shock, dizziness, vertigo, tinnitus, eye twitching, nausea and vomiting; Dizziness, tinnitus, headache caused by cerebral blood vessels; Symptoms of irritability, memory loss, lack of concentration are caused by cerebrovascular diseases; Peripheral circulatory disorders in Raynaud's syndrome; Isolated claudication, cyanosis of extremities, nutritional disorders, limb ulcers due to damage to peripheral blood vessels; Room for motion sickness, seasickness; Migraine pain.
3. Contraindications of Pyme Cinazin
Hypersensitivity to drug components. Patients with porphyria Note:
Pyme Cinazin and other H1 antihistamines can cause epigastric pain, so the drug should be taken after meals. The drug may increase symptoms of Parkinson's disease. Pyme Cinazin may cause drowsiness and dizziness in the early stages of taking the drug. Use caution when driving or performing tasks that require high concentration. The drug may give rise to extrapyramidal symptoms associated with depression if used in the long-term treatment of the elderly. Use Pyme Cinazin for pregnant and lactating women only in cases of real need. The drug increases the sedative effect when used with alcohol, CNS depressants, tricyclic antidepressants.
4. Dosage and usage
How to use
Take the medicine with a sufficient amount of water. Patients with vestibular disorders, peripheral circulation disorders should take the drug after meals. In case of motion sickness prevention, drink 30 minutes before departure and repeat after 6 hours if necessary. Dosage
Adults:
Vestibular disorders / cerebrovascular disorders: take 1 tablet x 3 times/day. Peripheral vascular disease: Take 2-3 tablets x 3 times/day. Dizziness 1 tablet x 3 times/day. Prevention of seasickness, motion sickness: Take 1 tablet about 30 minutes before moving; Repeat every 6 hours if necessary. Children: take 1⁄2 adult dose.
5. Side effects of drugs
Common
Drowsiness, somnolence. Digestive disorders. Uncommon
Feeling of dry mouth. Allergic reaction. Dull headache. Slight weight gain. Hyperhidrosis Rare
Extrapyramidal symptoms in elderly patients (tremors, muscle stiffness, slow walking,...) Hypotension (when using high doses)
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