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Proseadex Magnesi drug has the main active ingredients Magnesium lactate dihydrate, Magnesium pidolate and other excipients. Patients need to take the drug exactly as prescribed by the doctor to ensure effectiveness and avoid unwanted side effects.
1. What is the use of Proseadex Magnesium?
1.1. What is Proseadex Magnesium? The drug Proseadex Magnesi has the main active ingredient Magnesium lactate dihydrate; Magnesium pidolate; Corresponding to Mg2+ and Vitamin B6 (Pyridoxine hydrochloride). With sufficient excipients: Sodium citrate; citric acid; sodium benzoate; disodium edetat and orange essential oil; tartrazine; dibasic sodium phosphate; aspartame; sucralose; nipasol; nipagin; sodium carboxymethylcellulose; gum arabic; ethanol 96%, and purified water.
Proseadex Magnesi is a product of Ha Tay Pharmaceutical Joint Stock Company. Proseadex Magnesi is packaged in the form: Box with 6 blisters x 5 tubes containing 10 ml.
1.2. What are the uses of Proseadex Magnesium? Proseadex Magnesium is an OTC drug indicated for the treatment of:
Treatment of severe magnesium deficiency cases. When the patient is accompanied by calcium deficiency, in most cases magnesium must be compensated before calcium replacement. Treatment of functional disorders of anxiety attacks associated with hyperventilation (also known as visceral seizures) in the absence of specific treatment. Prevention and treatment of vitamin B6 deficiency: When the deficiency is due to nutrition, there are few cases of isolated deficiency of a vitamin of group B, so vitamin supplementation in the form of a mixture is more effective than when used alone. Ideally, the patient should still improve the diet. Deficiency of pyridoxine can lead to iron deficiency anemia, peripheral neuritis, seborrheic dermatitis and dry chapped lips. The body's requirements are increased and vitamin B6 supplementation may be necessary in the following situations: alcoholism, burns, congestive heart failure, persistent fever, gastrectomy, dialysis, and hyperthyroidism thyroid, bacterial infection, intestinal disease (eg, diarrhea, enteritis), or malabsorption related to hepatobiliary disease. Pregnant women have a need to strengthen vitamins, you should be supplemented by the diet. In some cases, doctors still recommend adding a mixture of vitamins and minerals, especially for those who are pregnant but have poor appetite or are at high risk of deficiency (twins or multiple pregnancies, smokers, etc.) alcohol and drugs). The need for all vitamins and minerals increases during lactation. Treatment of isoniazid and cycloserine toxicity. Some infants present with hereditary pyridoxine dependence syndrome. Pyridoxine should be used during the first week of life to prevent anemia and growth retardation.
2. How to use Proseadex Magnesium
2.1. How to use Proseadex Magnesi Depending on the condition and the patient, the doctor will prescribe the appropriate dose of the drug.
2.2. Dosage of the drug Proseadex Magnesium Adults: Severe magnesium deficiency: use 3 ampoules per day, or 300 mg Mg2+ over 24 hours. Seizures: use 2 oral ampoules per day, or 200mg Mg2+ over 24 hours. Children: Take 1 to 3 ampoules daily depending on age (100 to 300 mg Mg2+). The daily dose should be divided into 2 or 3 times: morning, noon and afternoon. When taking each time should drink with plenty of water. Taking a dose of 2mg per day is considered enough to supplement nutrition for people with normal absorption and digestion. Those who are pregnant and breastfeeding should supplement from 2 – 10mg per day. For the treatment of pyridoxine deficiency in adults, the usual oral dose is 2.5 to 10 mg of pyridoxine hydrochloride. After the absence of clinical symptoms of deficiency, a polyvitamin preparation containing 2 to 5 mg of vitamin B6 should be administered daily for several weeks. To treat drug-induced deficiency, the usual oral dose of vitamin B6 is 100-200mg per day. For the next 3 weeks, a prophylactic dose of 25 to 100 mg per day is used. For women taking oral contraceptives, the usual dose of vitamin B6 is 25 to 30 mg per day. For the treatment of convulsions in pyridoxine-dependent infants, a dose of 10 to 100 mg IM or IV is recommended. Seizures usually stop 2 to 3 minutes after the injection. Children with pyridoxine-responsive seizures usually require lifelong oral pyridoxine at doses of 2 to 100 mg/day. For the treatment of hereditary iron-cell anemia, the usual oral dose of pyridoxine is 200 to 600 mg per day. If after 1 to 2 months of treatment the disease does not change, another treatment must be considered. If there is a response, the pyridoxine dose can be reduced to 30 to 50 mg/day. Patients may need lifelong treatment with this vitamin to prevent anemia. To prevent anemia or neuritis caused by pyridoxine deficiency in patients taking isoniazid or penicilamine, vitamin B6 should be taken daily at a dose of 10-50mg. To prevent seizures in patients taking cycloserin, take pyridoxine at a dose of 100-300mg per day, divided into several times. For the treatment of convulsions or coma due to acute isoniazid intoxication, a single dose of pyridoxine equal to the amount of isoniazid taken orally is given, together with another anticonvulsant. Usually 1 - 4g pyridoxine hydrochloride intravenously, then 1g intramuscularly, every 30 minutes until the end of the dose. For the treatment of cycloserin overdose, 300 mg of pyridoxine hydrochloride is used daily. To treat acute hydrazine poisoning, use pyridoxine hydrochloride at a dose of 25 mg/kg, 1/3 intramuscularly, the rest intravenously over 3 hours. For the treatment of neurological effects caused by ingestion of mushrooms of the genus Gyromitra, pyridoxine hydrochloride is administered intravenously at a dose of 25 mg/kg over 15 to 30 minutes and repeated if necessary. The maximum total daily dose can be up to 15 to 20g. If diazepam is used in combination, a lower dose of pyridoxine may also be effective. Handling missed doses: It's still best to take Proseadex Magnesi on time as prescribed and guided by your doctor. Taking Proseadex Magnesi at the right time will ensure the best effect of the drug. Usually, the medicine can be taken 1 to 2 hours apart from the time ordered by your doctor. Patients should not take the supplement Proseadex Magnesium when the time is too far for the next dose.
Treatment of overdose: Symptoms: There is no information on overdose due to Proseadex Magnesi. Treatment: If an overdose of Proseadex Magnesium occurs, mainly symptomatic and supportive treatment.
3. Contraindications of Proseadex Magnesium
3.1. Contraindications Hypersensitivity to any of the ingredients or excipients of the drug. Severe renal failure with creatinine clearance less than 30 ml per minute. 3.2. Drug interactions Avoid using magnesium in combination with preparations containing phosphate and calcium salts, which inhibit the absorption of magnesium in the small intestine. In the case of combination therapy with oral tetracyclines, the two drugs must be taken at least 3 hours apart. Do not combine with levodopa, because levodopa is inhibited by vitamin B6.
4. Notes when using Proseadex Magnesium
Do not take Proseadex Magnesium with any other medicine containing magnesium or vitamin B6. When the patient has calcium deficiency, it is necessary to replace magnesium before calcium replacement. Use caution when using Proseadex Magnesium in patients with renal failure. After long-term use of pyridoxine at a dose of 200 mg per day, manifestations of neurotoxicity (such as severe peripheral neuropathy and severe sensory neuropathy) may have been observed. Use in pregnancy and lactation: This drug should be used in pregnant women only when clearly needed. Since magnesium is excreted in breast milk, the drug should not be administered to a nursing woman.
5. Side effects of Proseadex Magnesium
Digestive disturbances (diarrhea and abdominal pain) may occur. Rare: Hypermagnesemia. High doses of vitamin B6 can cause peripheral neuropathy. In addition, the patient informs the doctor about the unwanted side effects encountered when using the drug.
Carefully read the instructions on the storage of Proseadex Magnesi medicine listed on the package and the instruction sheet. Check the expiry date of the medicine before taking it. When not using Proseadex Magnesi, it is necessary to collect and handle according to the instructions of the manufacturer or the person in charge of medicine.
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