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Profentana is a non-steroidal anti-inflammatory, antipyretic and analgesic drug, containing the main ingredient Ibuprofen 400mg, prepared in the form of film-coated tablets. The drug is used to relieve toothache, pain after surgery, menstrual pain, inflammatory diseases of tendons/muscles/joints and fever.1. What are the effects of Profentana?
The main ingredient Ibuprofen in Profentana is a non-steroidal anti-inflammatory drug, derived from propionic acid. When entering the body, the drug inhibits prostaglandin synthetase, preventing the production of prostaglandins, thromboxane as well as other products of the enzyme cyclooxygenase (COX), thereby having anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen is considered the safest of the non-steroidal anti-inflammatory drugs.When used orally, the drug is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are reached after 1-2 hours. In the blood, large amounts of ibuprofen are bound to plasma proteins. Ibuprofen is eliminated mainly in the urine (1% unchanged, 14% conjugated with glucuronic acid). The anti-inflammatory effect of Ibuprofen becomes effective two days after taking the drug.
2. Indications and contraindications of Profentana
The drug is indicated for the purpose of anti-inflammatory, analgesic, antipyretic in the following cases:
Treatment of pain in pathologies such as: toothache, headache, postoperative pain, menstrual pain, muscle pain , backache. Treatment of musculoskeletal conditions such as rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, tendonitis, radiculitis, periarthritis of the shoulder. Antipyretic: Medicines used when prescribed by a doctor. Patients should not self-medicate because it can aggravate serious symptoms of the disease. Contraindications of the drug Profentana include:
Patients with hypersensitivity or irritation to the ingredients in the drug; Suffering from gastric and duodenal bleeding disease; History of asthma, bronchospasm; Liver or kidney failure, bleeding disorders; The patient is being treated with coumarin anticoagulants; Patients with hemorrhage, do not use antipyretic in case of dengue fever; Patients with congestive heart failure; Do not use in pregnant women in the last 3 months of pregnancy.
3. Dosage and how to take Profentana
How to use: The drug is used in oral form, swallow the tablet whole with a full glass of water immediately after eating to avoid irritation to the stomach.
Dosage:
Patients should consult a doctor before taking the drug or can refer to the following recommended dose:
Pain relief, inflammation reduction: Adults usual dose 1 tablet / time, 3-4 days time. The maximum daily dose of the drug is not more than 6 tablets. Antipyretic: Adults dose 1⁄2 - 1 tablet / time, the interval between oral doses is 4-6 hours, maximum not more than 3 tablets / day.
4. Undesirable effects of Profentana
In the process of using the drug may encounter the following undesirable effects:
Common: Fever, fatigue, abdominal bloating, nausea, vomiting, headache, dizziness, dizziness, rash, rash . Uncommon: Allergic rhinitis, urticaria, abdominal pain, gastrointestinal bleeding, insomnia, tinnitus, hearing loss, visual disturbance. Rare: Edema, Stevens-Johnson syndrome, alopecia, depression, impaired vision, leukopenia, cystitis. These adverse effects are transient and reversible upon discontinuation of the drug. In the course of using the drug, if the patient encounters any unwanted effects, it is necessary to stop the drug, notify the doctor for advice and proper treatment.
5. Notes when using Profentana
When taking Profentana, you should note the following:
Inform your doctor about the drugs you are using because some drugs can interact and affect the effectiveness of treatment, including: Antibodies Quinolones, stomach medicine containing magnesium hydroxide and aluminum hydroxide, methotrexate, furosemide, diuretics, Digoxin, other non-steroidal anti-inflammatory drugs. In case of overdose, the patient should be taken immediately to the nearest medical facility for treatment by methods: gastric lavage, induce vomiting and diuretics, give activated charcoal or salt bleach, in severe cases. dialysis or blood transfusion. Not recommended for pregnant women, especially in the last 3 months of pregnancy. Lactation: Ibuprofen passes into breast milk in low amounts, so if the mother is taking normal doses, the likelihood of a risk to the baby is low. Depending on the specific case to have indications to use the drug. There are no studies reported on the effects of the drug on people who are directly driving vehicles and operating machinery. Profentana is an anti-inflammatory, analgesic, and antipyretic drug. However, to ensure safe and effective use of the drug, you need to consult your doctor or ask a qualified pharmacist.
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