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Primocef belongs to the group of antibiotics whose main ingredient is Cefalexin. The drug is commonly used in the treatment of respiratory tract infections, urinary tract infections, skin and soft tissue infections.1. What is Primocef?
Primocef is an oral drug with the main ingredient Cephalexin - an antibiotic belonging to the 1st generation cephalosporin group, bactericidal effect by inhibiting bacterial multiplication through cell envelope synthesis.Primocef is effective against strains of Staphylococcus aureus including penicillinase-producing strains that are resistant to penicillin, E. coli resistant to ampicillin, strains of Enterococcus, positive Proteus indol and some enterobacter.
2. Uses of Primocef
Primocef is mainly used to treat the following Gram-negative and Gram-positive bacterial infections:Respiratory tract infections: Bronchiectasis, acute and chronic bronchitis, otitis media, sinusitis, sore throat. Genitourinary tract infections: Cystitis, recurrent urinary tract infections, gonorrhea, syphilis. Skin infections, soft tissue infections and bone and joint infections.
3. Dosage - how to take Primocef
Primocef is a drug absorbed from the gastrointestinal tract, usually used orally, 1 hour before meals. When using Primocef, it is necessary to adhere to the full treatment period (treatment time is usually 7-10 days even when the symptoms are gone), the dose is according to the instructions of the doctor and pharmacist. Adults:For adults, the dose in a day is from 1-4g divided into 3-4 times a day. Most cases respond to Primocef 500mg every 8 hours. In severe infections or infections with less susceptible organisms, higher doses may be considered. If a higher therapeutic dose of 4 g/day is required, a combination antibiotic or switching to an injectable antibiotic may be considered. For patients who are elderly or patients with renal impairment, caution should be taken to reduce the dose to suit the associated medical condition. For gonorrhea, use a single dose of Primocef in combination with Probenecid as prescribed by your doctor. Dosage Primocef for children:
For children, the usual dose is 25-50mg/kg body weight/day divided into 4 times a day every 8 hours. In severe infections, the dose may be doubled.
4. Contraindications of Primocef
Primocef is contraindicated for cases of hypersensitivity to the components of the drug.
5. Primocef side effects
When using Primocef, there may be some unwanted effects such as:
Systemic: Possible hypersensitivity reactions such as rash, urticaria, itching. More rarely, anaphylactic reactions, Steven Johnson syndrome, erythema multiforme, Quick edema, Lyell's syndrome, thrombocytopenia may occur. Digestive system: Nausea, vomiting, diarrhea, dyspepsia, digestive disorders, anorexia, abdominal pain, pseudomembranous colitis, reversible increase in liver enzymes, hepatitis. Central nervous system: Headache, fatigue, dizziness, tinnitus, anxiety, confusion, hallucinations. Genitourinary system: Vaginitis, genital pruritus, interstitial nephritis Precautions for use:
When using Primocef if there are symptoms of allergy such as difficulty breathing, swelling of the face, lips and tongue. .. must stop using the drug and need to go to the emergency room promptly. Long-term use of the drug may increase the growth of bacteria that are not sensitive to Cephalexin group, increasing the risk of superinfection with other groups of bacteria. If superinfection occurs, it is necessary to change or combine antibiotics according to the antibiogram. Use caution when using Primocef for patients with liver and kidney failure, patients with a history of gastrointestinal disease, especially colitis, and the elderly. When using the drug for a long time, it is necessary to periodically check the blood chart, liver and kidney function. Use with pregnant women: Be careful and consult your doctor, pharmacist before using in pregnancy, especially in the first 3 months. Primocef may be excreted in breast milk, so caution should be exercised when using the drug during lactation.
6. Drug interactions
When using Primocef with the following drugs, food and water may occur:
Primocef drug interacts with Probenecid drug groups. When using Primocef, it is possible that the Comb test may give a positive reaction or there may be a false positive reaction when the urine glucose is measured with Benedict's or Fehling's solution or Clinitest tablets. Using Primocef with alcohol, tobacco can affect the effectiveness of the drug.
7. Signs of overdose using Primocef
Primocef when used in excess will have the following symptoms: Nausea, vomiting, abdominal pain, diarrhea, possibly hematuria. Treatment: In case of simultaneous overdose, the patient should be monitored for vital signs, respiratory support, and electrolyte balance. In addition, with a dose of 5-10 times the maximum dose, gastric lavage or activated charcoal can be used to reduce the absorption of the drug in the gastrointestinal tract. Above is all information about Primocef drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Primocef for home treatment because there may be unwanted side effects.
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