This is an automatically translated article.
Phudstad 300mg is a drug belonging to the group of drugs for parasites, anti-infectives, antivirals, antifungals. The drug has the main ingredient Tenofovir disoproxil fumarate, which is indicated for the treatment of HIV-infected and chronic hepatitis B patients.
1. What are the uses of Phudstad 300mg?
1.1. What is Phudstad 300mg? Phudstad 300mg belongs to the group of antiviral drugs, with registration number VD-17517-12, manufactured by Phuong Dong Pharmaceutical Joint Stock Company - Vietnam.
Phudstad 300mg drug includes the following ingredients:
Main active ingredient: Tenofovir disoproxil fumarate 300 mg. Excipients: : Lactose, PVP, Primellose, Corn Starch/Corn, Sodium Lauryl Sulfate, Magnesium Stearate, Titanium Dioxide, HPMC, PEG, Brilliant Blue and Black. Phudstad 300mg is made in the form of long film-coated tablets, 300mg content, with many packaging forms such as boxes of 2 blisters, 3 blisters, 6 blisters, 10 blisters, each blister of 10 tablets or bottles of 30 tablets, 60 tablets , 90 tablets, 100 tablets and 250 tablets.
Phudstad 300mg is recommended for use by adults 18 years of age and older.
1.2. What are the uses of Phudstad 300mg? Phudstad is approved by the US Food and Drug Administration (FDA) for its effectiveness and safety in patients through 3 clinical studies: Helps reduce the progression of cirrhosis and the risk of cancer. liver.
Phudstad 300mg is indicated for the treatment of HIV-infected and chronic hepatitis B patients with compensated liver disease, with evidence of viral replication activity.
Contraindications:
Patients who are allergic to the main active ingredient Tenofovir Disoproxil Fumarate or any of the excipients of Phudstad 300mg. Children under 18. Severe kidney disease. Patients with abnormally low neutrophils (<0.75 x 109/liter) or abnormal hemoglobin levels (<75 g/liter).
2. Usage of Phudstad 300mg
2.1. How to use Phudstad 300mg Medicine Phudstad 300mg for oral use. Do not break, chew, crush but drink the whole tablet of Phudstad 300mg. Do not mix Phudstad 300mg with any other mixture. Use Phudstad 300mg as directed by your doctor 2.2. Dosage of Phudstad 300mg For normal patients:
Take 1 tablet/day. The medicine should be taken with a meal or a snack with a sufficient amount of filtered water. The body absorbs the drug best after a full meal. Eat foods rich in fat to increase the absorption of the drug. Patients with impaired renal function:
Creatinine clearance: > 50ml/min, 300mg/day as a normal person. Creatinine clearance: 30-49 ml/min, 300mg orally for 2 days. Creatinine clearance: 10 - 29 ml/min, 300 mg orally for 3-4 days. Patients on hemodialysis:
Take each dose 7 days apart or 12 hours after dialysis. Handling missed dose:
If you miss a dose of Phudstad 300mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose of Phudstad 300mg at the scheduled time. Note that the prescribed dose of Phudstad 300mg should not be doubled.
3. Note when using Phudstad 300mg
For the drug to be effective, people with HIV need to maintain a high level of the drug in their blood at all times, ie take it regularly, If for some reason the drug level drops low (due to irregular taking or half-treated) will facilitate the production of resistant viruses. Phudstad cannot kill HIV, it only stops its growth. Therefore, patients need to take Phudstad 300mg continuously for life. For all patients, Phudstad 300mg should be used with caution. Not all patients have to take Phudstad right away, but only those whose CD4 cell count drops to about 200 - 350/ml are prescribed drugs. Caution should be exercised in patients with renal and hepatic impairment (especially in patients with hepatitis C co-infection, being treated with Interferon and Ribavirin) and patients with a history of fractures or osteoporosis. Phudstad 300mg should only be used when clearly needed during pregnancy. HIV-1 infected mothers should not breastfeed to avoid the risk of HIV-1 transmission to the baby.
4. Side effects of Phudstad 300mg
During the use of Phudstad 300mg, patients may still experience side effects including:
Mild to moderate gastrointestinal disturbances such as: Abdominal pain, loss of appetite, indigestion, flatulence, nausea, vomiting and diarrhea. Headache, dizziness and fatigue. Skin rash may or may not be present. Very rarely, serum and pancreatic amylase concentrations may be elevated. Elevated liver enzymes, hepatitis, nephrogenic diabetes insipidus, nephritis, renal failure, acute renal failure, with effects on the adrenal ducts including Fanconi syndrome. There is accumulation or redistribution of body fat (fat formation) including abdominal fat, lipomas, tanning, gynecomastia, peripheral neuropathy, and cushing's syndrome present in these patients. antiretroviral therapy, including tenofovir disoproxil fumarate. Metabolic disorders such as hypercholesterolemia, hypertriglyceridemia, hyperglycemia, insulin resistance, and hyperlactatemia have been reported. Nucleoside reverse transcriptase inhibitors also cause mitochondrial dysfunction such as behavioral disturbances, anemia, seizures, hyperlipaemia, hypertonia, and neutropenia. Hyperphosphaturia, myalgia, myositis, and myopathy have been reported rarely, particularly when nucleoside analogues are used as HIV protease inhibitors Osteomyelitis has also been reported in patients with advanced HIV. development or in combination with long-term antiretroviral therapy. If experiencing these symptoms, the patient should stop using Phudstad 300mg and notify the doctor for appropriate treatment.
5. Drug interactions Phudstad 300mg
Need to control kidney function when using Phudstad 300mg with ganciclovir, valganciclovir. Insignificant interaction with Methadone. To avoid interactions, before being prescribed Phudstad 300mg, patients should inform their doctors about all the drugs they are using, including functional foods. The doctor will base it on that to prescribe the appropriate Phudstad 300mg.
6. How to store Phudstad 300mg
The shelf life of Phudstad 300mg is 36 months from the date of manufacture. Store in a cool, dry place, at a temperature not exceeding 25°C, in the original packaging, protected from light, and away from acidic environments. Keep Phudstad 300mg out of reach of children. The article has provided information on dosage, contraindications and notes during the use of Phudstad 300mg. To ensure optimal effectiveness of the drug and to prevent side effects, patients should consult their doctor or pharmacist before taking Phudstad 300mg.
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