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Phacotrivita belongs to the group of vitamin and mineral supplements with the main ingredients including vitamins B1, B6, B12. The drug is often used to treat vitamin B deficiency, growth retardation in children or other nervous system disorders. So how does Phacotrivita work?1. What are the effects of Phacotrivita?
Phacotrivita medicine has the main ingredients including vitamins of group B such as vitamins B1, B6, B12 with specific effects as follows:
Vitamin B1 or thiamin in the human body converted to thiamine pyrophosphate, which is responsible for decarboxylation of alpha - Ketoacids, such as pyruvate and alpha-ketoglutarate, have a role in pentose utilization in the hexose monophosphate cycle. In terms of pharmacokinetics, vitamin B1 is easily absorbed from the gastrointestinal tract and excreted in the urine. Vitamin B6 exists in three forms, pyridoxal, pyridoxine and pyridoxamine. When entering the body, it is converted to pyridoxal phosphate and partly to pyridoxamine phosphate. substances that act as co-enzymes that metabolize proteins, carbohydrates and lipids. Pyridoxine also participates in the synthesis of GABA in the central nervous system and participates in the synthesis of hemoglobin. Vitamin B12 or cobalamins act as co-transport enzymes involved in many important metabolic processes of the body. In particular, the two processes of folic acid metabolism and DNA synthesis are necessary for the reproduction of red blood cells and the metabolism of ketones to enter the Kreb cycle, necessary for lipid metabolism and normal functioning of the nervous system. terrible. Phacotrivita is usually indicated in the following cases:
Vitamin B group deficiency Children asthenia, growth retardation Neuralgia due to diabetes and alcohol Polyneuritis Paresthesia, shoulder-arm syndrome Nervous breakdown Sciatica Convulsions due to increased stimulation of the central nervous system. Shingles Prophylaxis and treatment of nausea and vomiting during pregnancy. Anemia due to deficiency of vitamins B6 and B12. Recovery and maintenance of health after illness, overwork or in the elderly. Contraindications of Phacotrivita include:
Patients with hypersensitivity to vitamin B1, vitamin B6 and other components of Phacotrivita. The patient has a malignant tumor. Patients with atopic allergies (asthma, eczema).
2. Dosage of Phacotrivita drug:
Depending on the subject and treatment goal, the dosage of Phacotrivita will be different, specifically as follows:
Adults: 1 tablet x 2 times/day Children over 12 years old: 1 tablet x 1 time/ Day Or other doses depending on the doctor's instructions When taking vitamin B6 in high doses (2-7 g/day) or more than 0.2 g/day for more than 2 months, the progression of sensory neuropathy with symptoms of ataxia, numbness of the limbs, but recovered after stopping the drug after 6 months.
3. Side effects of Phacotrivita:
In some patients when using Phacotrivita, side effects may occur such as:
Hypersensitivity reactions. Sensation of itching, stinging, urticaria. Sweating, insomnia. Vomiting, throat choking. Angioedema, respiratory failure. Cyanosis, pulmonary edema. Gastrointestinal bleeding. Vasodilation and transient hypotension. Stroke and death. Long-term use of high doses of vitamin B6 may worsen peripheral neuropathy.
4. Be careful when using Phacotrivita
Some general notes when using Phacotrivita:
The effectiveness and safety of Phacotrivita for children has not been evaluated. Do not use Phacotrivita preparations for pregnant women, because it can cause drug dependence syndrome in babies. Vitamin B6 can lead to inhibition of lactation by blocking the action of prolactin. Vitamin B1 may potentiate the effects of neuromuscular blocking agents. Vitamin B6 reduces the effectiveness of levodopa, but this interaction does not occur with a dopa decarboxylase inhibitor. Vitamin B6 reduces the activity of altretamine, reducing the concentration of phenobarbital and phenytoin in the serum. The above are the uses of Phacotrivita, users need to refer to and understand how to use the drug to achieve good results for the treatment process.
