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Ovaba 400mg is a psychotropic drug used in the treatment of epilepsy and neuropathic pain in adults. Refer to the following article to know the uses, ingredients and effective use of the drug.
1. Ingredients Ovaba 400mg
Ovaba is manufactured by Hilton Pharma., Ltd and is in the form of hard capsules.
Active ingredients: Gabapentin 400 mg Excipients: Tablertose 80 (lactose), magnesium stearate, refined talc,... Ovaba 400mg contains active ingredient Gabapentin which is structurally related to GABA and is being used in the treatment of epilepsy and peripheral neuropathic pain.
2. Indications and contraindications Ovaba
2.1 Indications Ovaba 400mg Peripheral neuritis in adults Patients with partial epilepsy with or without generalized seizures in adults and children > 12 years old. 2.2. Contraindications Ovaba 400mg People with hypersensitivity to the active ingredient Gabapentin and excipients contained in the drug Gabapentin.
3. Dosage and how to use Ovaba 400mg
3.1 How to take Ovaba 400mg Ovaba 400mg is used orally. The time of taking the drug does not depend on the time of taking the meal. In addition, Ovaba 400mg alone will not be effective, so the drug is used in combination with other antiepileptic drugs today.
Discontinuation of the drug should be done gradually over a period of at least 1 week and independent of the indicated dose. The maximum interval between doses should not exceed 12 hours.
3.2 Dosage Gabapentin dosage should be prescribed by a specialist, patients need to follow the doctor's treatment regimen for effective treatment results. Usually, the reference dose in some patients is as follows:
Anti-epileptic in adults and children > 12 years old
First day: 300mg/time x 1 time/day; Second day: 300mg/time x 2 times/day; The third day: 300mg/time x 3 times/day; The dose is then increased in increments of 300 mg daily, depending on the patient's response to the drug, and continued until an effective therapeutic dose is reached.
Usual dose: 900-1800mg/3 times/day not more than 2400mg/day.
The total dose of Gabapentin should be divided equally daily for each dose and the doses should not be more than 12 hours apart (may be divided into 4 times/day for high dose treatment).
Patients with impaired kidney function, hemodialysis need to reduce the therapeutic dose: Treatment dose should be adjusted based on the creatinine clearance index, usually recommended by the manufacturer as follows:
Hemodialysis: First use 300-400 then 200-300mg after 4 hours of hemodialysis.
Treatment of pain caused by peripheral neuritis, neuralgia due to shingles
Adults: use no more than 1800mg/divided into 3 times.
Or use the following reference dose:
Day 1: 300mg/time/day; Day 2: 300mg x 2 times/day; Day 3: 300mg x 3 times/day; The dose may then be increased in increments of 300 mg/day until 1800 mg/day and the total dose may be divided orally 3 times/day, based on the patient's response.
It should be noted: The above dosage is for reference only, the patient needs to take the drug exactly as directed by the doctor or pharmacist who prescribed the drug.
4. Possible side effects when using Ovaba
During the use of the drug, the patient may experience systemic side effects such as: Fatigue, headache, fever, weight gain, back pain,... Besides, there are some side effects that the patient may experience. in specific organ systems as follows:
Nervous system:
Dizziness; Sleepy; Ataxia, nystagmus; Tremor, dysarthria, amnesia, confusion, insomnia; Muscle twitching, dizziness, paresthesia, abnormal coordination. Digestive system:
Nausea, vomiting; Abdominal pain, indigestion, constipation, diarrhea; Increased palatability. Respiratory system:
Rhinitis; Sore throat; A cough; Respiratory tract infections. Skin: Rash, pruritus, acne and maculopapular rash.
Psychogenic function: Depression or agitation.
Genitourinary system: Impotence.
Musculoskeletal system : Muscle pain and fatigue.
Cardiovascular system: Vasodilation.
Blood and lymphatic system: Purpura and leukopenia.
Note: Side effects of Ovaba 400mg can occur individually or massively, depending on the location of each patient. So tell your doctor about any side effects you experience.
5. Ovaba 400mg . drug interactions
During the examination and prescription, the patient should notify all drugs being used so that the doctor can give the most accurate drug interaction warnings. Some Ovaba 400mg interactions are as follows:
Some drugs can increase the CNS depressant effect of Gabapentin such as: Brimonidine, Alizapride, Blonanserin, Azelastine, Brexanolone.... Antacids containing magnesium and Aluminum can increase the effectiveness of Gabapentin (if needed, use 2 hours apart). Combining Morphine with Gabapentin may increase the plasma availability of Gabapentin. Gabapentin may decrease the Cmax and AUC values of hydrocodone.
6. Ovaba overdose and treatment
There is no specific information on Ovaba overdose. However, when using an overdose, the patient may experience some symptoms such as: Double vision, lethargy, slurred speech, mild diarrhea, drowsiness, ... In this case, the patient can be indicated symptomatic treatment.
For patients with renal failure who experience an overdose of Gabapentin, hemodialysis may be indicated.
7. Some Precautions When Using Ovaba 400mg
Patients need to be careful and note some issues during the use of Ovaba 400mg as follows:
Use caution when using in subjects with renal failure, because the creatinine clearance plays an important role in the elimination. except Ovaba. Children under 12 years of age and women who are pregnant or breastfeeding need to be cautious. Elderly: People > 65 years old should be aware of possible side effects, adjust the dose based on the patient's renal function. Treatment in people with impaired renal function: People operating machinery, driving or doing concentration work need to be careful when taking Gabapentin; Hopefully, with the information about the drug Ovaba 400mg, it will help patients answer the question "what does Ovaba do" and help the patient use the drug to be effective, safe and effective. good for treatment.
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