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Orazime 100 is a prescription medication used in the treatment of a number of bacterial infections today. Patients should use Orazime 100 under the guidance of a doctor or professional pharmacist.
1. What is Orazime 100?
1.1 Ingredients contained in Orazime 100: Active ingredient: Orazime 100 contains Cefpodoxime 100mg (equivalent to 130.45mg Cefpodoxime Proxetil) along with Excipients: Povidon, Avicel, Magnesium stearate, Sodium lauryl sulfate, Avicel, Croscarmellose sodium, Hydroxy propylmethyl cellulose, Titanium dioxyd, Lactose, Hydroxy propylmethyl cellulose, Magnesium stearate, Talc, Polyethylene glycol 6000, sun yellow, Erythrosin red... just enough for one film-coated tablet.
1.2 Mechanism of action of the drug Orazime 100 Orazime 100 contains Cefpodoxime which is a 3rd generation cephalosporin antibiotic. Cefpooximed Proxetil is effective against Gram-positive and Gram-negative bacteria and the drug has high stability against the attack of bacteria. β-lactamases.
2. Indications of Orazime 100
Orazime 100 is prescribed by a specialist. Normally Orazime 100 is used to treat the following mild to moderate bacterial infections:
Lower respiratory tract infections:
Pneumonia caused by bacteria S. pneumoniae or H. influenzae (including strains producing β-- lactamases). Chronic bronchitis in acute exacerbations caused by strains of S treptococus pneumoniae, Haemophilus influenzae or M. catarrhais. Upper respiratory tract infections:
Acute maxillary sinusitis caused by bacteria: Haemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis; Acute bacterial otitis media: Streptococcus pneumoniae, Haemophilus influenzae (including β-lactamase-producing strains), or Moraxella (Branhamella) catarrhalis. Pharyngitis and/or tonsillitis, caused by the bacteria Streptococcus pyogenes. Certain sexually transmitted diseases:
Acute, uncomplicated cervical and urethral gonorrhea caused by Neisseria gonorrhoeae; Infection with Neisseria gonorrhoeae in the anus - rectum of women; Skin and Skin Structure Pathology: Uncomplicated skin and skin structure infections caused by Staphylococcus aureus or Streptococcus pyogenes.
Urinary tract infections: Cystitis caused by bacteria Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis or Staphylococcus saprophyticus.
Before starting treatment with antibiotic Orazime 100, the patient should have a laboratory test to help isolate and identify pathogenic bacteria. After the test results are available, the application of Cefpodoxime to treatment will bring high efficiency and accuracy.
3. Contraindications of Orazime 100
Orazime 100 is contraindicated for use in some specific subjects as follows:
People with Porphyrin metabolic disorders; Patients with renal insufficiency; Patients with hypersensitivity to drugs of the Cephalosporin group (Cefpodoxime, Cefazolin, Cephalexin, Cefadroxil, Cephalothin, cefotaxime, cefixime, cefoperazone, ceftazidim, ceftizoxime, ceftriaxone,...) and Penicillin;
4. Unwanted effects when using Orazime 100
During the use of Orazime 100, depending on the location of each patient, the side effects are different. Usually, patients may experience some side effects as follows:
Common side effects: Nausea, vomiting, diarrhea, headache; Allergic reactions: rash, urticaria, itching. Uncommon side effects: allergic reactions, serum sickness-like reactions with symptoms: arthralgia, rash and fever, anaphylactic reactions; Skin erythema multiforme; The liver experiences liver enzyme disorders and temporary cholestatic jaundice. Rare side effects: Blood disorders, eosinophilia, reversible interstitial nephritis, increased muscle tone and dizziness, increased agitated activity, trouble sleeping, confusion. Patients should inform their doctor about the side effects encountered while using Orazime.
5. Dosage and how to use Orazime 100
5.1 Adults + children > 13 years old: Patients with chronic bronchitis or acute pneumonia: Cefpodoxime 200mg / time (12 hours / time) for 10-14 days. Patients with pharyngitis, tonsillitis, urinary tract infections: Cefpodoxime 100mg / time (12 hours / time) for 10-14 days. Patients with skin infections: Cefpodoxime 400mg / time (12 hours / time) for 10-14 days. People infected with gonorrhea in the urethra: Cefpodoxime 200mg, followed by oral doxycycline to prevent Chlamydia infection. 5.2 Children by age: Children 5 months to 12 years old with acute otitis media: Cefpodoxime 5mg/kg (maximum dose 200mg) x twice daily or 10mg/kg (maximum dose 400mg) x 1 time/day, treatment for 10 days. Children 5 months to 12 years old with bronchitis, tonsillitis: Cefpodoxime 5mg/kg (maximum dose 100mg) x 2 times/day, treatment duration 5-10 days. Renal impairment: use the usual dose, each dose is 24 hours apart.
6. Orazime 100 . drug interactions
Cefpodoxime will be reduced absorption when used with some common stomach antacids such as:
Proton pump inhibitors H2 blockers Prostaglandins antacids... To ensure the effective use of Orazime Ideally, the patient should inform the doctor of all medications being taken.
7. Some notes when using Orazime 100
In the process of learning and using Cefpodoxime, patients need to be careful about a number of issues as follows:
Pregnant and nursing women should consult a doctor before using Cefpodoxime. Orazime medicine should be stored away from light. Patients should not use Orazime that has expired. A history of drug allergy should be obtained before using Cefpodoxime. Long-term use of Cefpodoxime can lead to bacterial and fungal superinfection The article provides information on the use of Orazime 100, dosage and precautions for use. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Orazime exactly as directed by your doctor. Store Orazime in a dry place, the temperature does not exceed 30 degrees Celsius and out of the reach of small children.
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